Exercise studio
seeks to attract
millennials with
new venue
By EMILY DAVIES
Daily Staff Reporter
Exercise studio Pure Barre is
adding to its hundreds of stores
nationwide with the addition
of a downtown studio in Ann
Arbor, opening on East Liberty
Street, in an aim to increase
the demographics it attracts.
The store is the second in Ann
Arbor, with another on Oak
Valley Drive.
Two years ago, Pure Barre
moved to its Oak Valley Drive
location after a studio on Felch
Street, closer to the University
of Michigan, failed to meet the
company’s needs. Anna Locke,
an owner of the Oak Street
studio and of the new studio on
East Liberty, said the location
didn’t provide the right amount
of space.
“Our current studio started
downtown
on
Felch
Street
and then we moved locations
a few years ago just because
of parking and our studio at
the time could not fit nearly
as many people as our current
studio can,” Locke said. “We
just outgrew that location.”
With their earlier move,
however, came a loss of younger
customers.
“After we moved to this
current location, we lost a
certain demographic,” Locke
said. “We lost a lot of college
students and young working
professionals from downtown,
so
our
goal
going
back
downtown and moving into
Liberty is that we are going to
target that demographic and
bring Pure Barre back to those
people.”
Pure Barre is a barre studio
that uses the ballet barre,
body weights and small space
movements
to
build
lean
muscle mass. The workouts are
popular among some University
students, such as LSA freshman
Lexi Dubreuil.
“I like that it’s lower impact
stuff,” Dubreuil said. “I have
a lot of shin problems from
running track in high school,
and it gives me a way to stay
toned and in shape without
doing a lot of high-impact
stuff.”
LSA freshman Sarah Guss,
who said she plans to join Pure
Barre’s studio on East Liberty,
echoed Dubreuil’s sentiments.
“I love how challenging it
is and how you are told the
parts of your body that you are
working out in the class. I also
feel like you’re getting a great
workout and it burns but you
don’t break much of a sweat.”
The studio is expected to
open in June.
2 — Thursday, March 10, 2016
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The Michigan Daily — michigandaily.com
ON THE DAILY
AVA RANDA/Daily
Ann Arbor resident Libby Hunter at a weekly protest on
Main Street, outside Governor Rick Snyder’s appartment on
Wednesday
PROTEST ON M AIN
The University of Michigan’s
own
Daniel
Passino’s
audition for NBC’s The Voice
has
generated
organized
student support of their
classmate.
Passino is a senior study-
ing opera in the school of
Music, Theatre and Dance.
In his audition, Passino
sang the Charlie Puth and
Meghan Trainor song “Mar-
vin Gaye.” Blake Shelton
and Christina Aguilera both
turned around in their seats
indicating that they wanted
to mentor Passino, and he
ultimately opted to join Team
Christina for the upcoming
season of the Voice.
“You have been one of my
biggest idols and inspira-
tions,” Passino told Aguilera
as he accepted a spot on her
team.
Passino tweeted last night,
thanking all those who sup-
port him on his musical jour-
ney
In addition to those who
viewed it live on television,
a video of the audition post-
ed on The Voice’s Youtube
channel had gathered over
147,680 views in only 24
hours, and this number con-
tinues to grow.
Passino’s friends and peers
at the University are excited
to support their classmate.
LSA
sophomore
Michael
Funkhouser is a friend of
Passino and said he has no
doubt of his impending suc-
cess.
“The first time I met Dan-
iel he was singing and right
away I noticed how passion-
ate he was about what he
does,” Funkhouser said. “He
doesn’t just sing, he doesn’t
just listen to music. He’s con-
stantly working on getting
better, he’s honestly one of
the hardest working people I
know. Whether he wins The
Voice competition or not he’s
going to achieve his dream
one way or another, I know
it.”
Pure Barre opens second Ann
Arbor location on Liberty St.
420 Maynard St.
Ann Arbor, MI 48109-1327
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THREE THINGS YOU
SHOULD KNOW TODAY
Daily
Arts
writers
profile a new club on
campus that works to
create spontaneous art, such
as spreading bubble wrap
throughout the Diag.
>> SEE B SIDE on 1B
2
CAMPUS EVENTS & NOTES
Career Crawl
- Gap Year
WHAT: Learn about
gap year opportunities
including fellowships,
research, volunteering,
internships and
jobs by talking to
Michigan grads.
WHO: THE
Career Center
WHEN: 12 p.m.
to 1:30 p.m.
WHERE: Pond Room
- Michigan Union
A chemical and biological
weapons expert and
member of the Islamic
State being held in U.S.
custody in Iraq said militants
plan to use mustard gas as
a weapon, according to The
New York Times. Sleiman
Daoud al-Afari once worked
for
Sadaam
Hussein’s
Authority.
1
Reading and
Book Signing
WHAT: Nina McConigley,
author of “Cowboys and
East Indians,” will read a
selection from her fictional
work and sign books.
WHO: Nina McConigley
WHEN: 5:30 p.m. to 6:30
p.m.
WHERE: Museum of Art -
Helmut Stern Auditorium
Kyle Odom, suspected
of shooting a pastor
in Idaho, went to the
White House to deliver
a manifesto, which admits to
the plotting of the murder as
a part of an alien conspiracy
to control the human race,
on Wednesday according
to The Washington Post.
3
Penny Stamps
Speaker Series
WHAT: A talk given
by the vice president of
cognitive computing at
IBM Research, who leads
an international team
creating the next generation
of cognitive systems.
WHO: Guruduth Banavar
WHEN: 5:10 p.m. to 6 p.m.
WHERE: Michigan Theater
First
Derivatives
Coffee Chats
WHAT: Speak one-on-one
with a representative of the
First Derivatives recruiting
team. Learn about working
for a leading provider of
products and consulting
services.
WHO: The Career Center
WHEN: 9 a.m. to 4 p.m.
WHERE: The Career
Center Office
Gossip Stoppers
WHAT: Learn how to
create a positive workplace
environment by decreasing
negativity and gossip.
Learn how to identify and
address these issues and
improve job satisfaction
and productivity. This
program has a fee of $179.
WHO: April Callis -
Learning and Professional
Development (LPD)
WHEN: 1 p.m. to 5 p.m.
WHERE: Administrative
Services Building
Careers for
Ph.D.s
WHAT: Learn about the
MBTI theory and career
options outside of academia.
Find a non-academic career
that matches your personality.
RSVP through Handshake.
WHO: Career Center
WHEN: 3:30 p.m. to 5 p.m.
WHERE: Career Center
- Program Room (3003)
Digital Music
Ensemble
WHAT: Aided by the audience,
composer and musician Judy
Dunaway will perform her
Balloon Symphony. She is
known for electro/acoustic work
with balloons.
WHO: Judy Dunaway
WHEN: 7 p.m.
WHERE: Earl V. Moore
Building
Gifts of Art
WHAT: The Vocal Arts
Ensemble of Ann Arbor
will perform a program
called “Rumor Has It,”
consisting of songs about
gossip. This will be a
mixture of classical,
musical theater and jazz
music.
WHO: Vocal Arts
Ensemble (VAE)
WHEN: 12:10 p.m. to 1
p.m.
WHERE: University
Hospitals - Main Lobby
Unlike
adult
with
brain
tumors,
children
cannot
receive
radiation
therapy
because children’s brains have
a highly impermeable blood-
brain barrier, meaning most
chemotherapeutic agents are
not responsive.
Carl Koschmann, a cancer
specialist at the UM Mott’s
Children’s Hospital and the first
author of the study, explained
children with high-grade glioma
are even more challenging to
treat.
“Pediatric
high-grade
glioma remains very difficult
to treat effectively, and most
children will not survive beyond
two years of receiving this
diagnosis,” Koschmann said.
“The difference is that some
of the tools that work for other
cancers, including surgery and
radiation, are difficult to use on
a child’s brain. Chemotherapy
works for some brain tumors, but
high-grade glioma is resistant to
almost all chemotherapy.”
The
inability
to
use
chemotherapy has led to the
exploration of several alternative
methods of treatment, including
DNA damaging drugs.
DNA-damaging drugs have
existed for many years and are
used for various purposes in
adult patients, but University
researchers have found that,
when used on the new model
mice, they shrank the size of
their brain tumors.
One-third of children with
brain tumors have a mutation in
the ATRX protein that already
helps repair damage to the cells
— Castro said by furthering that
damage to the cells with the
drugs, they were able to kill it all
together.
“If you have bad mutations,
your DNA is unstable, so you
treat it with a drug that induces
further damage, and the cell
dies more readily, that means
you are going to be able to treat
these children in a better way,”
he said.
Third-year medical student
Flor Mendez worked on the
research project, and said she
thought the progress they have
made will help future treatment.
“Our work on the role of
ATRX mutations, prevalent in
pediatric GBM, uncovered that
ATRX deficient tumors have
a defect in a mechanism of
DNA repair which makes them
more sensitive to therapies that
induce DNA damage to destroy
tumor cells,” she said. “This
knowledge
will
help
guide
the development of improved
therapies
for
patients
with
ATRX mutations.”
Other University researchers
within the same lab have also
been working to develop new
treatment techniques through
immunotherapy,
which
the
mouse model can also be used
for. That form of treatment
trains the immune system to
recognize and attack cancer
cells, which Castro said is
incredibly difficult due to the
complex nature of cancer cells.
“Tumors have mechanisms
by which they can hijack the
immune
system,
they
trick
the immune system and they
become kind of invisible so what
you need to do is unmask it,”
Castro said. “And you need to be
able to allow the immune system
to be able to see the tumor as an
invader in a way as they would
see a bacteria or a virus.”
The new mouse model
allows for developments in
immunotherapy
because
the model has a fully
functioning
immune
system Castro said. Most
models
currently
used
for research take tumors
from human patients to
prepare cells for testing,
but these cells are not
compatible with animal
models.
Therefore,
researchers
cannot
test
immunotherapeutic
strategies.
Lowenstein said he finds
immunotherapy appealing
as a scientific avenue for
treatments for a variety of
reasons.
“The ability to harness
the power of the immune
system to treat cancer is a
very attractive treatment
modality
for
these
devastating
childhood
brain cancers, as it could
provide an effective, safe
and non-invasive treatment
strategy,” Lowenstein said.
AVA RANDA/Daily
The new Pure Barre location at 539 E. Liberty St.
RESEARCH
From Page 1A
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