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May 09, 2013 - Image 3

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Michigan Daily Summer Weekly, 2013-05-09
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Thursday, May 9, 2013
The Michigan Daily - michigandaily.com

Thursday, May 9, 2013
The Michigan Daily - michigandaily.com

COSTOLO
From Page 1
heart regarding his career after
taking an acting class his senior
year. It turned out to be more than
"saying Arthur Miller lines to each
other," so he took another course
the next semester and began stand-

up comedy. Turning down pro-
gramming job offers, he moved to
Chicago to try his hand at impro-
visational comedy with the Second
City, the famous theater company.
Costolo offered the picture-
perfect version of how life in
Chicago could have panned out,
then explained the reality.
"In the real-world story of what
happened, I decided to make a big

bet on myself and take the chance
to do this because it's what I love,"
Costolo said. "I was grinding away
for a long time and had no money,
and we would rehearse during
the day and perform these little
theaters at night for free and I was
taking classes during the day at
Second City, as well, trying to learn
improvisation and eventually had
to get out because I had no money.

"So I put my CS degree from
Michigan to use wrapping flatware
and selling place settings at Crate
and Barrel."
Improvisation, he said, is less
than a skill than an expectation
for graduates as they follow their
passions.
He passed on advice given to
him by a director at Second City:
"The beauty of improvisation

Call: #734-418-4115
Email: dailydisplay@gmail.com

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RELEASE DATE-Thursday, May9, 2013
Los Angeles Times Daily Crossword Puzzle
Edited by Rich Norris and Joyce Nichols Lewis
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4sanny

2013-14
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is you're experiencing it in the
moment, if you try to plan what the
next line will be, you're just going
to be disappointed," he said.
To end his often humorous
remarks, Costolo invoked myriad
careers University graduates
would pursue and had advice no
matter where they end up: "Be
right there, and nowhere else, in
that moment. Soak it all it. And
remember to say thank you."
In an interview after
commencement, Costolo said, "You
have this intellectual sense of how
big the crowd is, but until you go
out there and experience it, you
don't really have an appreciation
for it."
"You have to have a north
star," he said of the path - or
lack thereof - he endorsed, "but
you can't constantly worry about,
'Well, and then I'm supposed to
do this,' because life doesn't work
that way and you won't experience
your life. You'll be living it in
service to some expectations that
are fiction."
LSA graduate Anisha Chadha
was the only student speaker on
Saturday. Though she came to
the University concerned about
how she would feel among some
25,000 undergraduates, Chadha
said joining student organizations
allowed her to create a small,
unique community on campus.
"I realized, no matter what
we were doing, it was almost
impossible for me to feel small,"
Chadha said in her address. "Even
when I was in this Big House, with
114,803 other people, I began to
realize that what I was feeling
was not smallness, but rather I
was feeling like I was a part of
somethingbigger than myself."
Though most use the term
"Michigan Difference" to describe
the academic and cultural caliber of
the University, Chadha explained it
as the impact Michigan graduates
can have on humanity.
"It is the difference we were
given the opportunity to make,"
Chadha said. "It is the knowledge,
the empathy and the skills we
have gained here that are needed
to be able to make a thoughtful
difference in the lives of others."
As she concluded her speech,
Chadha reminded her fellow
graduates that they represent
the University and the power
of its graduates in their future
endeavors.
"Always remember: you are
contributing to our class's 'Michi-
gan Difference' and the differ-
ence made by all of the Wolverines
before us."

Parents kicked you out of
your house this summer?
We'll take you in.
Join the summer Daily staff!
Contact: kgburke@michigandaily.com
[nw-nwM

BEHAVIOR
From Page 1
Brown said she believes there
has been an increase in reports
of suspicious behavior due to the
release of the safety bulletin in
April. She added that people are
now offering this information
to University Police while it
may have been less reported
previously.
Because the suspects for each
of these incidents do not match
in description, Brown said rather
than a sudden trend of suspicious
behavior occurring, the trend
lies within the increase of people
reportingthe behaviors.
In a recent incident, a man -
described as white, in his 60s,

5'5" to 57" and with white hair -
approached pedestrians on State
Street and asked them on dates.
While the University Police were
unable to locate the suspect, his
description does not match that
of the suspect from the North
Campus incidents.
Brown added that upon receiv-
ing a report, University Police offi-
cers go to the scene to attempt to
find a potential suspect. In most
cases no actual crime incidents
may have occurred and these
acts of suspicious behavior do not
warrant an ongoing investigation
from the University Police.
If approached with suspicious
behavior, Brown said to imme-
diately call the University Police
and provide a description of the
suspect.

Researchers decode
molecular message
leading to spread of
malignant cells
By SAM GRINGLAS
Daily StaffReporter
In a School of Dentistry lab
on North University Avenue,
researchers have discovered
what could eventually change
the way doctors treat cancer.
In a study published Tuesday
in the online journal Nature
Communications, Dentistry
Prof. Russell Taichman and
Research Associate Younghun
Jung have deciphered the
molecular messages that cause
certain cancers to spread.
Taichman's lab studies how
cancer spreads to bone marrow
as well as ways in which stem
cells can be used to regenerate
bone. The research is significant
in the School of Dentistry
because bone regeneration
is often crucial in dental
procedures.
Jung, who is involved in
research in both areas, decided to
join the two sets of experiments
rather than perform the studies
separately.
Both malignant and benign
tumors emit distress signals to
SMOKING
From Page 2
Violating the regulations of the
smoke-free initiative is a violation
of the Statement of Student
Rights and Responsibilities. A
student who breaks the rules and
is reported by another student
or staff member must report to
the Office of Student Conflict
Resolution.
The ban has remained a con-
troversial issue since its incep-
tion, hailed by some opponents as
an infringement on personal free-
dom. Among other problems, an
opinion article in The Michigan
Daily from March said a smoke-
free campus that takes away ash-
trays for smokers to use leads to

'U' discovery may change
way doctors treat cancer

recruit healing cells, or very
small embryonic-like stem cells.
While studying the effect of
VSEL stem cells in rehabilitating
human bones inserted in mice,
Jung decided to include a tumor
in the experiment to see how the
VSEL cells would interact. In
the initial trial, Jung found the
tumor contained a huge amount
of the healing cells.
"I was ecstatic to find that
they do, in fact, interact with
each other," Jung wrote in an
e-mail interview. "As a scientist,
I get excited just by coming up
with new ideas and theories to
test. But when the data seems to
support these ideas, it is really
something else."
After almost three years of
research, Taichman and Jung have
been able to discover what draws
the healing cells to a tumor. While
a collaborator at the University of
Louisville first identified VSEL
cells, Taichman and Jungwere the
first to study them in tumors and
pinpoint the role the cells play in
the spread of cancer.
When a tumor develops,
the tumor produces a protein
that draws the VSEL stem cells
inside. Then, the VSEL cells turn
into a second type of cell known
as cancer associated fibroblasts.
Those cells produce a protein
that makes cancer cells more
aggressive, allowing them to
spread to other parts of the body.
an increase in littering. That said,
there are some designated ash-
trays around campus.
Another issue commonly
reported is uncertainty about the
boundaries of the ban. Though
Winfield said the ban has been
largely successful, there have
been a handful of people who take
advantage of the relatively lax
rules.
Rather than turn to law
enforcement, Winfield would pre-
fer to solve the issue more amica-
bly.
"Some are angry about the
rules, defiant, not aware or don't
care and are taking advantage of
the fact that we're using light-
weight enforcement," he said.
"My first preference is to improve
signage and advertising."

By understanding the ways
in which stem cells interact
with a tumor and cause cancer
to spread, researchers can now
study methods through which to
block VSEL cells from interact-
ing with a tumor. Additionally,
high VSEL cell levels in a blood
test could potentially serve as a
diagnostic meter for detecting
cancer earlier.
Taichman said it is possible
that further research in block-
ing VSELs could potentially cre-
ate a cure for cancer. Currently,
Taichman's lab is attempting to
find inhibitors to block the cells
as he applies for further fund-
ing to continue the research
and approval for human trials.
Jung said the next steps involve
investigating the healing cells'
interaction throughout the pro-
gression of a cancerous tumor.
However, Taichman said
many scientists still debate the
existence of VSEL stem cells
due to their small size and the
difficulties associated with
identifying them.
Taichman said reviewers
may also question whether
the findings will remain true
in other types of cancers.
Cancerous prostate tumors are
typically used in Taichman's
lab because they often spread
to other parts of the body, such
as bones. The lab has also tested
breast cancer tumors.
Lena Gray, the smoke-free
environment project coordinator
for Michigan Healthy Commu-
nity, said in a press release that
smoking is still an issue on Cen-
tral Campus.
"We are pursuing other
approaches such as adding sig-
nage and sidewalk chalk messag-
es, to remind everyone that those
areas are smoke-free," Gray said.
University President Mary
Sue Coleman convened a Smoke-
Free Advisory Committee at the
inception of the ban that meets
regularly to address issues such
as littering and boundary recog-
nition.
There are currently 1,159 com-
pletely smoke free campuses -
including the University - across
the U.S.

51 Body shop's
reappraisal
55 Spheres
57 Reid or Robbins
58 Deg. for Dilbert
creator Scott
Adams
59 Deee useful in
navigation, or in
discovering the
hidden Same in
the answers to
starred clues
65 Honeys
66 Lowly laborer
67 Party animals?
68 Respondsto the
MAILER-
DAMON
DOWN
1 30 Rock'
network
2 Cry of wonder
3 One-fifth of DLV
4 WestrAffican
capital
5 Sporty

[T

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m e per oa oz unezna tmrougn .une
8th. Volunteers wsill join us for meals
and cultural outings. Interested
persons should contact Lyn Badala-
menti at 734-822-3122 or badalamen-
til@pittsfield-mi.gov
HANDYPERSONNEEDED. Experi-
ence preffered but not necessary.
Please email DFBemail@gmail.com
PERSONAL/HOUSEHOLD ASSIS-
TANT WANTED
for a busy professional. Please email
resume to DFBemail@gmail.eom

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(c)O1 nTori ne edia Serices.Inc.

05/09/13

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