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Monday, July 16, 2007
The Michigan Daily - michigandailycom
U' research shines light on Alzheimer's
By ARIKIA MILLIKAN
Daily News Editor
When Matthew Chapman wan
studying the bacteria that cauoe uri-
nary tract infections five years ago
as part of his post-doctoral research
at Washington University, he never son why we're studying these pro-
expected that it would lead him to teins," said Chapman, who is now
study the bacteria's connection to an assistant professor in Molecular
Alzheimer's disease at the Univer- Cell and Developmental Biology.
sity of Michigan. While Chapman explored how
"The UTI thing was sort of an the bacteria commonly known
inroad, a first glimpse and the rea- as E. coli colonize the bladder, he
observed that the bacteria were
producing a certain type of mis-
folded fiber that is associated with
incurable diseases like Alzheimer's,
Huntington's and Creutzfeld-Jacob,
the human version of Mad Cow dis-
"It was one of those com-
pletely sort of 'Eureka' surprising
moments," Chapman said.
Amyloid fibers present in the
neurological systems of patients
afflicted with such diseases are
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