- 11. i A +TT e-% Al T1"1Tl T T1
The Michigan Daily - Monday, December 9, 1998 - 7
N I
esearchers produce
cows in Japanese lab
eCloning other mammals may b
The Washington Post
Scientists in Japan have cloned several calves from
a single adult cow, the third species of mammal to be
genetically duplicated after sheep and mice, and the
most commercially important animal to be cloned to
date.
The new work, the first cloning of a cow to be ver-
ified by scientists, represents the most efficient appli-
tion of cloning technology yet. Eight cows were
Worn from 10 attempts, far more than the single sheep
named Dolly born after more than two dozen
attempts.
Moreover, several of the cloned calves were made
from a kind of cell never before used in cloning exper-
iments. That suggests there may be many ways to copy
a cow - and perhaps easier ways still to be discovered
for cloning other mammals, including humans.
Most immediately, the cloning of cows promises a
simplified method for expanding herds of valuable
*eeds, such as prize beef cattle or dairy cows that
make more or better milk.
In the longer run it could help scientists engineer
herds of identical cows that make human medicines in
their milk - an avenue of research that is already
advancing in cows that were mass-produced by crud-
er and less efficient techniques.
"This says this technology is here, it's repeatable,
and we're going to see it moving into the biomedical
and agricultural industry, said James Rob, a profes-
sor of veterinary reproduction and developmental
iology at the University of Massachusetts in
mherst. "This is not like when Dolly came out, when
all we could say was, 'This was done once.'" The new
research "clearly tells us that ... the efficiency is high
enough to see it being used commercially."
The growing parade of cloned animals is testimony
to the complete overthrow of a long-standing biologi-
cal axiom that said adult mammalian cells are inca-
pable of growing into entirely new animals. Adult
cells are fully "differentiated," the theory went --
meaning they had become skin, muscle, bone or other
tissues - and could never revert to the blank-slate
state of an embryo cell, which holds the potential to
grow into every kind of tissue.
The realization that adult cells can be forced to
grow into embryos is now spurring a revolution in
agriculture and medicine.
Five surrogate mother
cows carried two calf
embryos apiece.
The newly cloned calves, made by scientists at
Kinki University in Nara, Japan, are not the first to be
grown from adult cow cells. New Zealand scientists
said in August they had made a calf from a single cell
taken from the last remaining cow of a rare breed
there. And five other Japanese groups claim to have
made clones of adult cows.
But the Kinki group is the first to describe its results
in sufficient detail to get the work published in a sci-
entific journal - the benchmark of proof demanded
by other scientists. Their work will appear in Friday's
issue of the journal Science.
ANIMAL CARETAKING jobs for
interested & motivated students. For info call
Linda Faaberg at 764-0277.
ANN ARBOR'S BIGGEST sports bar is
now hiring Waitstaff & Floornen -- Flexible
hours -- hardworking -- punctual applicants.
Apply today @ Scorekeepers across from
Borders.
ARRIBA NOW HIRING Full or part time
pim. servers, cooks, and prep cooks. Exp. not
quired. Call for interview after 2 p.m. 662.
85.
ATTENTION STUDENTS!!
MI TELEFUND is hiring!! Create your own
schedule, gain valuable computer &
communication skills. Paid training, fun
atmosphere. Up to $8/hr. Bonuses galore!
For application & info stop by 611 Church
#304 or call 998-7420.
CLERKIMESSENGER, $7.25/hr. 10
hrs./wk., Mon.-Fri., 1-3pm. Drivers license
quired..UM Central Campus. Call Denise
7312 for interview. E.O.E.
COMPUTER ASSISTANTS-- Freshmen
or Sophomores for the Winter 1999 and
following Terms to assist with maintaining
Macintosh hardware, software and LAN as
part of the Student Publications computer
support team. Good pay, flexible hours.
Resumes or letters explaining background
and interests are helpful. Call for3job
information and interview. 936-7883 or
inquire at dafriedo@umich.edu
DO YOU HAVE A WORK STUDY
GRANT? Positions available 8-10, 12:30-3
& 4-5:30 Monday through Friday at U of M's
dund House Children's Center, working
Math young children. Located at Forest &
Willard. Please call 998-8440 for more
information or to arrange an interview.
DRIVERS EARN $8-iS/HR. Full or P/T
days, evenings., & latenight. Flex. sched.
Apply at Pizza House 618 Church. 995-5095.
EARLY CHILDHOOD JOB for early
birds. Help open our center from 7:30-9:30
M-F. Starts Jan. 4. $7/hr. Help feed children
breakfast and get their day off to a good start.
Call Pat at 668-0887.
ADDLE PLAYER LOOKING for vocal
up to accompany. 741-9012.
GOLDEN RETREIVER SEEKING dog
lover for mid-day walks on weekdays.
$30/wk. 622-8050.
HOUSECLEANER/MORNINGS organize,
file, projects, errands, yard, pets, MAC skills.
Mon.-Sat. min. 9-1 pm. $8-$10/hr. 769-2795.
LAW FIRM, FULL time, paid assistant
position avail., no prior experience necessary.
Must be avail. in Dec. Fax resume to 734-
662-3893 immed., or send to 308 W. Huron,
Ann Arbor, MI 48103.
DELS NEEDED (Female and Male) for
t e Lifedrawing Classes at Eastern Michigan
University. Must be at least eighteen years
old- Paying $9.00 an hr. For more
information call 734-487-1268.
MOTHER'S HELPER NEEDED: 4-6
hrs./wk. $10/hr. 662-9888.
MOTION PICTURE PR/AD Agency seeks
creative, organized and enthusiastic student
for PAID PR/Promo winter internship (30-40
hrs./wk. - starting 1/4/99). PR, Adv, Comm,
Journalism majors preferred. Must be self-
t tivated and follow through on various
ks. Some evenings necessary; must have
reliable car and solid computer skills. Fax
--,resume to: Julie Tontapanish, Solomon
Friedman Advertising (248) 540-2281.
NATIONWIDE SEEKING part time/full
time medical billers. Up to 35k/yr. No
medical exp. nec. PC req. 1-800-921-9939.
DRFCEPTINIST POSITION avaiIahI at
RESEARCH DATA COLLECTION AND
PROCESSING: The University of Michigan,
Survey Research Center Survey Lab is now
recruiting people with excellent
communication skills & interest/background
in the social/economic sciences to join a team
collecting national public opinion telephone
interviews. Work to begin mid-Jan.
Candidates need to be highly self-directed
with a professional telephone manner for
conducting research interviews. Experience
with IBM compatible computers helpful.
Keyboard/typing skills required. Must be
avail. to work at least 16-20 hrs./wk, nearly
exclusively evenings & weekends.
Competitive wages--starting at $9.50/hr.
Demonstrated Spanish ability may increase
wage. Apply in person, weekdays 8:30 a.m.-
5 p.m., at the University of Michigan
Institute for Social Research, Rm. 3350, 426
Thompson St., Ann Arbor from 121/798
through 12/15/98. The University of
Michigan is an Equal Opportunity,
Affirmative Action Employer.
SCOREKEEPERS IS NOW hiring cooks
for the fall and winter. No exp. nec.
Hardworking, punctual applicants apply at
310 Maynard next to Kinkos.
SPECIAL GIFT - We're looking for healthy
women between the ages 21-35 for egg
donation. All ethnic backgrounds are
encouraged. Fee paid. Send inquiries to
AARMA, P.O. Box 2674, Ann Arbor, MI
48106.
SPEND YOUR SUMMER - in a lakefront
cabin in Maine! Camp Mataponi, a
residential girls camp, has over 50 staff
openings for Watersports, Athletics, Tennis,
Ropes Course, Outdoor Adventure, Arts &
Dance, Group leaders and more. Make life
long friends while you enjoy outstanding
facilities. Top salaries plus room/board and
travel included. On site interviews will be
conducted. Call us today at 888-684-CAMP
or email: mataponil@aol.com
SUMMER CAMP - Counselors wanted.
Friendly Pines Camp, located in the cool pine
mountains of northern Arizona, is looking for
summer counselors for the 1999 season. For
more information, call 520-445-2128 or
email info@friendlypines.com
TENANTS UNION - Great Work Study Job,
flexible hours. Start now or in Jan. Counsel
renters, prevent homelessness, learn to run a
non-profit. Call 936-3076.
THE UM MUSEUM of Natural History is
now accepting applications for docents.
Employment to begin in January. Duties
include leading guided tours and educational
programs for children. Work-study and non-
work-study positions available. Experience
with children a plus. Apply in person in the
Museum Store, on the first floor of the
Ruthven Bldg. For more info., e-mail Kelly
at kelsul@umich.edu
WANTED: 100 STUDENTS. Lose 5-100
lbs. New metabolism breakthru RN asst. Free
gift guaranteed. $35 fee. 800-940-5377.
*ACT NOW! Call for best
prices to South Padre(free mea
Jamaica, Keywest, Panama
needed...Travel free, earn c
discounts for 6+. www.leis
/800-838-8203.
Nobody Does .
DAIVZ YOURSELF &
-U":
8 cloned
ecome easier
As with all previous adult cloning efforts, the
Japanese team started with a single cell from the adult
to be cloned. In Dolly's case that cell was taken from
a sheep's udder. The Japanese researchers used so-
called cumulus cells taken from a cow's ovaries (the
same kind of cell that researchers in Hawaii used to
clone mice) or skin cells taken from that cow's fallop-
ian tubes - a kind of cell never before used for
cloning.
The scientists placed those cells in laboratory
dishes, each one resting alongside a cow's egg
cell whose own genetic material had been
removed. An electrical shock forced each pair of
cells to fuse into one. Mysterious natural com-
pounds inside the egg cells "erased" the genetic
memories of the donor cells, in effect making
each donor cell "forget" it was an ovarian cell and
begin to divide as though it were part of a newly
developing embryo.
Two by two, 10 such embryos were transferred from
their dishes into five surrogate mother cows. Eight
developed to maturity and were born, seven naturally
and one surgically. Four died soon after birth from
infections and other "environmental" causes, but all
appeared normal, the team reported.
The researchers said they had another batch of
clones developing now, made from liver, kidney
and heart cells, with births expected in the
spring.
Will Eyestone, a senior research scientist at PPL
Therapeutics' research farm in Blacksburg, Va., said
cow cloners are driven in large part by the desire to
make herds of cows that make human medicines in
their milk.
Spring Break AAA! SPRING BREAK TRAVEL was 1
als), Cancun, of 6 small businesses in the US recognized
city. Reps. by Better Businesses Bureaus for outstanding
ash. Group ethics in the marketplace!
uretours.com springbreaktravel.com 1-800-678-6386.
SPRING BREAK -Reps Wanted.
Acapulco 7 nights air & hotel from $569/
- Better! person quad. Other destinations avail. Please
call Dan @ Regency Travel AMX. 665-6122.
SnnngRrea itra Velws°o 6s t e s~Si h
SAVS g Ue* se
ge e' i 1 q V e econied foroutstandingethic sby
" D nair of Bter BUSiness Bureaus
Bahamas Party
r Cruise -279
5 Days Most Meas - Free Parties + includes Taxes
Cancun $399
7 Nghts Air + Hote*Free Food & 30 Hours of Drinks
3 amalca439
sNightsAir + Howtelsave S150on Food & Drinks
Hlodda $119
Panama City, DaytonaSouth Beach & cocoa Bech
Spring Break .aver -Our 2th Yeart
S1-800-678-6386
SASE
ERVATIONS SPRING BREAK '99- Panama City
9! Beach-The Boardwalk Beach Resort-Spring
Break Headquarters. Packages from $19.00
per person. Closest to Spinnaker and La
~-Vela. Host of Sports Illustrated Beach Club.
- VCall Now! 1-800-224-GULF.
* www.springbreakhq.com
WK SPRING BREAK 2X1 EARLY
1 IRD SPECIAL INCLUDES:
FREE 32 hours of drinks, 14
LS! meals
plas $459, HELP WANTED: Organize 8
people and travel free
$399 + taxes
1-800-574-7577 ext. 118
EDRINKS! www.surfandsuntours.com
osBaa MEXICO, CKUISES,
I Plan JAMAICA, BAHAMAS,
shtours.com LAS VEGAS
.MM .mm.
# STAMOS FAMILY OF TRAVEL. Call
I 663-4400. Student Travel Breaks 663-4400.
! U-M Faculty/Staff Special Line 663-5500.
# Located in Kerrytown mall downtown A2.
#
#
Ham crnaaC4_ nnouncements
limited
~ Aft
BREAK PACKAGE
One chance for
every $25 sold
:._.
MIDNIGHT MADNESS
BUYBACK PARTY
Tuesday, December 15th...
* free munchIest
S* holiday singers
* giveaways
Free picture with Santa for all
canned good donationsand
buybacks
Okay, here's the latest
SELL YOUR BOOKS HERE...
*Get the most CASH back
*Enter the drawing for the
FREE CANCUN SPRING
i
I
C4
w
r "
1-80Q-SUNCH
DOMESTIC INFORMATIRN & RESE
i New for 199
1-888-SuNCH
INTERNATIONAL INFORMATION & RE
www.sunchase.c
#1 SPRING BREAK SPECIAl
Book early & receive a free mea
Cancun & Jamaica $399, Ba
Florida $99. 1-800-234-7007
www.endlesssummertours.com
A #1 SPRING BREA
HOURS & HOURS OF FREE
Earn 2 FREE Trips & $
Cancun,Jamaica,Florida,Barbad
Lowest Prices/ Best Mea
1-800-426-7710/www.sunspla
Call today Space Is
I
, ITravel SI...
* 121S. UnvifyAnn Abor Lowo
* 9 9 .@2OFl
i Ca a
.
mm mmmm.stitmm mm mm
STOREWIDE SALE
20% off
Everything *
December 13-20
*excluding textbooks
i
i
Michigan Union
Boktr
2 GREAT KIDS need afternoon babysitter
Mon. Competitive pay. Call 662-4805.
CHRISTMAS BREAK CHILDCARE
needed for 5 yr. old. 3 days only, 13 hrs. each
day. Must have own transportation. 973-
6298.
QUALITY CHILD CARE needed for our
toddler. Part-time. 913-9870,leave message.
SITTER/DRIVER WITH safe, reliable car
for 1 child starting in January. Mon. 3-4:30 &
Fri. 3-6. Generous pay. 665-4719.
I5'I
I
p~fl I
I
I
U
I
I
I
@ 7f427U
U74779I
I
*§764476I
s
t
1
v
**TOP 49 COMICS Top 49 comics
www.cartoonstrip.com Top 49 comics.
A A 100'-V !!DlWiT -P k.. S '
I
A LARGE GROUP of Men's t& Women's
Dr. Marten shoes- $79.90!!! At Mast Shoes,
619 E. Liberty St.
LESSONS-STRINGS-WIND-PIANO. You
can play today- Herb David Guitar Studio
302 E. Liberty 665-8001.
VIRBRANT ANN ARBOR,1999 Calender
(lower level in the union)
A Barnes & Noble College Bookstore
I