8
Thursday, June 28, 2018
The Michigan Daily — michigandaily.com
NEWS
1014 VAUGHN AVAIL Fall 2018
#1 is being rented by the room for $700/m
including utilities
If you have a group of 5, rent the whole unit
for $3100 plus Electric to DTE
#2 is a 6 Bdrm for $3720 plus Electric to
DTE • 734‑996‑1991
1015 PACKARD
3 Bdrm Apt Avail Fall 2018
2 parking space, onsite laundry, 1st floor
$2250 + $120/month for electric to DTE
Call 734‑996‑1991
CENTRAL CAMPUS, FURNISHED
rooms for students, shared kitch., ldry.,
bath., internet, rent from $700 and up.
Call 734‑276‑0886.
HOUSES AVAILABLE FALL 2018
1016 Packard ‑ 4/6 Bdrm ‑ $3080‑$4020
401 Pauline ‑ 4 Bdrm ‑ $2900
827 Brookwood ‑ 4 Bdrm ‑ $2900
Showings M‑F 10‑3 • 734‑996‑1991
Classifieds
Call: #734-418-4115
Email: dailydisplay@gmail.com
FOR RENT
ACROSS
1 Barfly
4 Covered with
new grass
10 Quick snooze
13 “Fortunate Son”
band, briefly
14 Imagines
16 “Science Friday”
host Flatow
17 Generous nature
19 S&L offerings
20 Fortified
Portuguese wine
21 Lingering traces
23 Eternally
24 Org. Edward
Snowden worked
for
27 Cigna rival
28 Exercising
control over
one’s own affairs
31 Ultrasound goo
32 One who minds
his manor
33 Bridal bio word
34 Speak (up)
37 Arabian
Peninsula
resident
39 Admit, with “up”
40 World Cup chant
41 Persian Gulf
republic
42 CBS forensic
series
44 1945 Physics
Nobelist who
discovered the
exclusion
principle
48 Bottled water
brand
49 “__ out!”
50 Minor dents
53 Church official
55 “Just watch me!”
57 Programming
pioneer Lovelace
58 Eighteen holes ...
and a hint to this
puzzle’s circled
letters
61 Hubbub
62 Blinking diner
sign
63 Asian New Year
64 “District 9” extras
65 Blended
66 Texter’s “No
way!”
DOWN
1 Loser
2 Indian, for one
3 Baseball deals
4 Go unused
5 Musk, e.g.
6 Neutralize, as a
snake
7 Peace Nobelist
Hammarskjöld
8 WWII zone
9 Take-out order?
10 Ingredient in
therapeutic gum
11 Battle of the
Bulge region
12 Excerpts
15 Microchip found
in cameras,
briefly
18 Go back on a
promise
22 One with nest
eggs
25 One-named “A
Seat at the
Table” singer
26 HarperCollins
romance imprint
29 Native plants
30 CNN
correspondent
Hill
34 Coca-Cola sports
drink
35 “Two thumbs
up!”
36 New Orleans
NBA team
38 Quite a few
39 Clerk’s chore
41 Deliberately
overlook
43 Decongestant
brand
45 Blubber
46 Rated (oneself)
highly
47 All things
considered
51 Clay being of
Jewish folklore
52 Introduction to
geometry?
54 Ramble
56 Essence
59 4 x 4, for short
60 Art Ross Trophy
org.
By Christopher Adams
©2018 Tribune Content Agency, LLC
06/28/18
06/28/18
ANSWER TO PREVIOUS PUZZLE:
RELEASE DATE– Thursday, June 28, 2018
Los Angeles Times Daily Crossword Puzzle
Edited by Rich Norris and Joyce Nichols Lewis
Report details
developments in
synthetic biology
By SAYALI AMIN
Daily Staff Reporter
Michael Imperiale, an esteemed
microbiology
and
immunology
professor at the University of
Michigan,
recently
chaired
a
national committee to help write a
report that aimed to prioritize and
identify potential threats in the
advancing field of synthetic biology.
The report, titled “Biodefense in
the Age of Synthetic Biology,” was
sponsored by the U.S. Department
of Defense and published by the
National Academies of Science,
Engineering, and Medicine.”
According
to
Imperiale,
synthetic biology alters biological
organisms through various types of
computational and design methods.
“Synthetic biology refers to a set
of concepts, approaches and tools
that facilitate the modification or
creation of biological organisms,”
Imperiale said. “These approaches
are, for the most part, founded in
engineering principles.”
While synthetic biology has
many positive contributions to
society such as biofuels and new
drug development, Imperiale said it
also has the capability to do harm.
“The Department of Defense
asked the National Academies to
take this study because they really
wanted to get some advice about
what the potential vulnerabilities
with respect to biodefense would be
due to this emerging technology,”
Imperiale said.
Patrick
Boyle,
an
organism
designer at Ginkgo BioWorks Inc.
who also helped author the report,
has direct experience with the
synthetic biology industry.
“When I was a graduate student
in synthetic biology less than 10
years ago, I synthesized about 10
genes over the course of my entire
thesis work,” Boyle wrote in an
email interview. “At Ginkgo, my
team designs tens of thousands of
genes every month for synthesis.
This work gives me a perspective
on how ‘bad actors’ might use
synthetic biology if they have a
lot of resources and large teams at
their disposal.”
Imperiale explained the process
of writing this report could be
broken down into two parts.
“The first thing we did was to
come up with a framework for how
to look at these capabilities that are
enabled by synthetic biology and
then determine how much concern
should we have about any of these
capabilities,” Imperiale said. “In
the second part what we did was
apply the framework to a series of
capabilities that we thought were
the most obvious to think about.”
The report ranks 12 capabilities
of synthetic biology in terms of
their potential threat to society
based on the framework created.
Altering bacteria ranks near the top
of the list, according to Imperiale.
“One of the ones we thought was
of most concern was modifying
bacteria to make them more
dangerous,” Imperiale said. “For
example, someone could take a
bacterium that causes disease and
engineer it so that it’s now resistant
to antibiotic treatment; it’s now
much harder to treat.”
The framework is intended to
apply to any new developments in
synthetic biology that may arise in
the future as well.
“Biotechnology
is
changing
rapidly, so our ranking of threats
in the report itself is just a snapshot
of
current
capabilities,”
Boyle
wrote. “I expect the framework
itself to be more enduring as it
anticipates that the barriers and
bottlenecks limiting the nefarious
uses of synthetic biology will be
challenged by new discoveries.”
In an email interview, Nina Lin,
chemical
engineering
associate
professor at the University, wrote
her lab uses synthetic biology to
address issues of renewable and
sustainable fuel as well as chemical
production.
“It’s very important to point out
that the synthetic biology research
community is very aware and
proactive to the dual use of this
highly promising and powerful
technology,” Lin wrote. “Almost
at every major synthetic biology
conference, there are sessions
dedicated to the safety issues where
researchers and other experts come
together to discuss and formulate
preventive plans.”
U-M prof discusses
dangers of biotech