with normal cells in the same 
individual.

“The basic idea is, based on a 

patient’s molecular fingerprint, 
to suggest clinical trials or off-
label use of approved agents 
based on the mutational profile 
of 
an 
individual 
advanced 

cancer, or, in general, metastatic 
disease,” Chinnaiyan said. “By 
matching a patient’s molecular 
fingerprint with potential drugs 
that target those aberrations, we 
have a better chance at treating 
cancer in a precise or rational 
fashion.”

The University is licensing 

the MI-ONCOSEQ panel to 
Tempus. Clo Ewing, director 
of communications at Tempus, 
wrote in an email interview that 
the health-tech company aims 
to commercialize the genomic 
panel and provide access to 
clinicians 
and 
health 
care 

specialists nationwide.

“Our 
partnership 
with 

University of Michigan will allow 
patients across the country to 
benefit from clinically validated 
technology that UofM has been 

developing for years,” Ewing 
wrote. “Combined with our 
interactive analytic and machine 
learning platform will support 
physicians across the country 
working to deliver personalized 
cancer care.

Chinnaiyan 
noted 
that 

because each cancer has unique 
molecular 
characteristics, 

genetic sequencing of tumors 
can provide physicians evidence 
for decision-making in treatment 
methods.

“For example, not all breast 

cancers are the same,” he said. 
“They are caused by different 
gene aberrations and knowing 
those in a more precise fashion, 
we hope that we will be able to 
deliver more durable therapies 
for cancer patients.”

He added that the previous 

treatments for cancer such as 
chemotherapy 
and 
radiation 

were relatively non-specific.

“While you attempt to try and 

hit cancer cells, you often hit 
normal cells as well,” he said.

Since 2011, MI-ONCOSEQ has 

been utilized for more than 1,500 
patients, sequencing between 12 
and 25 patients a week.

Chinnaiyan also explained 

that MI-ONCOSEQ is reasonable 

in 
cost 
and 
turnaround 

time 
for 
delivering 
results. 

Previous approaches to genome 
sequencing 
had 
an 
average 

turnaround time six to eight 
weeks, whereas MI-ONCOSEQ 
takes about 10 days.

With the shifting paradigm 

in 
personalized 
medicine, 

MI-ONCOSEQ allows clinicians 
across the country to provide 
personalized 
cancer 
care. 

Costs for genome sequencing 
have 
significantly 
decreased 

over the past decade, making 
it 
more 
affordable 
and 

accessible, according to Ewing. 
Simultaneously, 
technological 

advancements allow for larger 
quantities of data analysis.

“Together, this means we are 

at a point in time where we can 
empower physicians to make 
real-time, data-driven decisions, 
which we hope will result in 
more time for people living with 
cancer,” Ewing wrote.

The 
unique 
partnership 

between the University and 
Tempus is facilitated by the 
close 
relationship 
between 

Chinnaiyan and the health-tech 
company’s laboratories.

Furthermore, 
the 

collaboration extends beyond 

just the panel.

“We work closely with 

Arul as he has agreed to 
become a scientific advisor 
to Tempus,” Ewing wrote. 
“We’ve developed a very 
close 
relationship 
with 

our labs cooperating on an 
almost daily basis.”

Chinnaiyan said he sees 

patients for MI-ONCOSEQ 
after 
they 
have 
failed 

multiple other treatments, 
at which point the cancer 
is evolved and difficult to 
treat.

“I think, moving into 

the future, the hope is 
that this technology of 
comprehensive 
molecular 

analysis of tumors, basically 
this 
next-generation 

sequence 
analysis, 
will 

be 
brought 
to 
earlier 

stage 
cancer 
patients,” 

he 
said. 
“By 
matching 

that combination of gene 
alterations with the right 
combination of treatment, 
we hope to be able to achieve 
more durable responses for 
cancer patients.”

The undefeated, third-

ranked Michigan football team 

may have had a bye-week this 

past weekend, but head coach 

Jim Harbaugh certainly wasn’t 

taking it easy.

On a recruiting trip to 

El Cerrito High School in 

California, Harbaugh attended a 

football game and worked on the 

‘chain gang’ — assisting officials 

with the down markers — in 

exchange for a steak sandwich, 

the Detroit Free Press reported.

“The chain gang needed 

a guy and I was promised 

a tri-tip steak sandwich at 

halftime, that’s all I needed 

to hear,” Harbaugh said on 

Monday during his weekly press 

conference. “That was a lot of 

fun.”

Known for his unusual 

recruiting trips, Harbaugh has 

had sleepovers and climbed 

tees in the past in attempts to 

impress prospects. On this trip, 

Harbaugh visited four-star 

outside linebacker recruit Aaron 

Banks at El Cerrito High. He 

also announced the homecoming 

queen on Friday at Antioch High 

School in California where he 

was visiting the top prospect in 

the country, running back Najee 

Harris, ESPN reported.

Harbaugh’s enthusiasm for 

steak is also well documented. 

He posted a picture of himself 

and wife Sarah on twitter at 

Ruth’s Chris Steak House in 

Ann Arbor last week, after a 

promotion gave customers a 

percentage off their final bill 

based on the Michigan football 

team’s margin of victory. 

Michigan defeated Rutgers 

78-0, the largest margin of a 

victory since 1939, meaning the 

steakhouse offered customers 

the maximum of 50 percent off 

their bills during the following 

week.

“Ruth’s Chris & Buzz Goebel! 

Sarah, me & Ann Arbor thank 

U for being such good sports! 

Plus the Steaks are A++, Mercy!,” 

Harbaugh’s tweet read.

BACK TO THE GRIND.
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2A — Wednesday, October 19, 2016
News
The Michigan Daily — michigandaily.com

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Had a beautiful drive back 
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CAMPUS EVENTS & NOTES

Poetry Slam Night

WHAT: UM Poetry Club will 
co-host an amateur poetry 
slam night with cash prizes, 
in conjuction with a special 
Museum of Archaeology exhibit.
WHO: Kelsey Museum of 
Archaeology
WHEN: 7 p.m. to 9 p.m.

WHERE: Kelsey Museum of 
Archaeology

Guatemala Birding Talk

WHAT: Lecture by Washtenaw 
Audubon Society about the group’s 
recent bird-watching trip to 
Guatemala.
WHO: Matthaei Botanical Gardens 
& Nichols Arboretum
WHEN: 7:30 p.m. to 9 p.m.

WHERE: Matthaei Botanical 
Gardens

Swing Dancing 

WHAT: Opportunity for 
interested students to check out 
swing dancing and meet new 
people. 
WHO: Student Organizations: 
Mswing
WHEN: 8:30 p.m. to 10 p.m.

WHERE: Michigan League, 
Room D

Presidential Debate 
Viewing 

WHAT: Viewing open to 
students and faculty of the final 
presidential debate, sponsored 
by the Department of Political 
Science. 
WHO: Undergraduate Political 
Science Association
WHEN: 9 p.m. to 10:30 p.m.

WHERE: Palmer Commons 

U.S.-China Economic 
Relations Lecture
WHAT: Former World Bank 
Chief Economist Justin Lin 
and Ford Prof. John Ciorciari 
to give lecture on the future of 
economic relations.
WHO: Gerald R. Ford School 
of Public Policy
WHEN: 4 p.m. to 5:30 p.m.

WHERE: Weill Hall, 
Annenberg Auditorium

Medical School 
Interviewer Event
WHAT: Prospective students 
will have the opportunity to 
listen to and ask questions of an 
interviewer from the University 
of Michigan Medical School. 
WHO: Student Organizations: 
Sports Medicine Club
WHEN: 7 p.m. to 8:45 p.m.

WHERE: CCRB, Bickner 
Auditorium

STEM Study Abroad

WHAT: Information session 
for students to hear about study 
abroad opportunities in science, 
technology, engineering and 
math. 
WHO: Center for Global and 
Intercultural Study 
WHEN: 5 p.m. to 5:30 p.m.

WHERE: Undergraduate 
Science Building, Room 1230

Law Day 

WHAT: The Career Center will 
host an event for prospective 
law students to meet with 
representatives from more than 
100 different law schools. 
WHO: Newman Academic 
Advising Center
WHEN: 11 a.m. to 2 p.m.

WHERE: Michigan Union

ON THE DAILY: HARBAUGH JOINS ‘CHAIN GANG’

KEVIN ZHENG/Daily

Bonnie, a Ann Arbor resident, gets her face painted as part of the Harvest 
Festival at Cobblestone Farm in Ann Arbor Tuesday.

FALL FESTIVITIES

The Michigan Daily (ISSN 0745-967) is published Monday through Friday during the fall and winter terms by students at the 
University OF Michigan. One copy is available free of charge to all readers. Additional copies may be picked up at the Daily’s 
office for $2. Subscriptions for fall term, starting in September, via U.S. mail are $110. Winter term (January through April) is 
$115, yearlong (September through April) is $195. University affiliates are subject to a reduced subscription rate. On-campus 
subscriptions for fall term are $35. Subscriptions must be prepaid. The Michigan Daily is a member of The Associated Press and 
The Associated Collegiate Press.

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