Exercise studio 
seeks to attract 
millennials with 

new venue

By EMILY DAVIES

Daily Staff Reporter

Exercise studio Pure Barre is 

adding to its hundreds of stores 
nationwide with the addition 
of a downtown studio in Ann 
Arbor, opening on East Liberty 
Street, in an aim to increase 
the demographics it attracts. 
The store is the second in Ann 
Arbor, with another on Oak 
Valley Drive.

Two years ago, Pure Barre 

moved to its Oak Valley Drive 
location after a studio on Felch 
Street, closer to the University 
of Michigan, failed to meet the 
company’s needs. Anna Locke, 
an owner of the Oak Street 
studio and of the new studio on 

East Liberty, said the location 
didn’t provide the right amount 
of space.

“Our current studio started 

downtown 
on 
Felch 
Street 

and then we moved locations 
a few years ago just because 
of parking and our studio at 
the time could not fit nearly 
as many people as our current 
studio can,” Locke said. “We 
just outgrew that location.”

With their earlier move, 

however, came a loss of younger 
customers. 

“After we moved to this 

current location, we lost a 
certain demographic,” Locke 
said. “We lost a lot of college 
students and young working 
professionals from downtown, 
so 
our 
goal 
going 
back 

downtown and moving into 
Liberty is that we are going to 
target that demographic and 
bring Pure Barre back to those 
people.”

Pure Barre is a barre studio 

that uses the ballet barre, 
body weights and small space 
movements 
to 
build 
lean 

muscle mass. The workouts are 
popular among some University 
students, such as LSA freshman 
Lexi Dubreuil.

“I like that it’s lower impact 

stuff,” Dubreuil said. “I have 
a lot of shin problems from 
running track in high school, 
and it gives me a way to stay 
toned and in shape without 
doing a lot of high-impact 
stuff.”

LSA freshman Sarah Guss, 

who said she plans to join Pure 
Barre’s studio on East Liberty, 
echoed Dubreuil’s sentiments.

“I love how challenging it 

is and how you are told the 
parts of your body that you are 
working out in the class. I also 
feel like you’re getting a great 
workout and it burns but you 
don’t break much of a sweat.”

The studio is expected to 

open in June.

2 — Thursday, March 10, 2016
News
The Michigan Daily — michigandaily.com

ON THE DAILY

AVA RANDA/Daily

Ann Arbor resident Libby Hunter at a weekly protest on 
Main Street, outside Governor Rick Snyder’s appartment on 
Wednesday

PROTEST ON M AIN

The University of Michigan’s 
own 
Daniel 
Passino’s 

audition for NBC’s The Voice 
has 
generated 
organized 

student support of their 
classmate.

Passino is a senior study-

ing opera in the school of 
Music, Theatre and Dance.

In his audition, Passino 

sang the Charlie Puth and 
Meghan Trainor song “Mar-
vin Gaye.” Blake Shelton 
and Christina Aguilera both 
turned around in their seats 
indicating that they wanted 
to mentor Passino, and he 
ultimately opted to join Team 
Christina for the upcoming 
season of the Voice.

“You have been one of my 

biggest idols and inspira-
tions,” Passino told Aguilera 
as he accepted a spot on her 
team.

Passino tweeted last night, 

thanking all those who sup-
port him on his musical jour-
ney

In addition to those who 

viewed it live on television, 
a video of the audition post-
ed on The Voice’s Youtube 
channel had gathered over 
147,680 views in only 24 
hours, and this number con-
tinues to grow.

Passino’s friends and peers 

at the University are excited 
to support their classmate. 

LSA 
sophomore 
Michael 

Funkhouser is a friend of 
Passino and said he has no 
doubt of his impending suc-
cess.

“The first time I met Dan-

iel he was singing and right 
away I noticed how passion-
ate he was about what he 
does,” Funkhouser said. “He 
doesn’t just sing, he doesn’t 
just listen to music. He’s con-
stantly working on getting 
better, he’s honestly one of 
the hardest working people I 
know. Whether he wins The 
Voice competition or not he’s 
going to achieve his dream 
one way or another, I know 
it.”

Pure Barre opens second Ann 
Arbor location on Liberty St.

420 Maynard St.

Ann Arbor, MI 48109-1327

www.michigandaily.com

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THREE THINGS YOU 
SHOULD KNOW TODAY

Daily 
Arts 
writers 

profile a new club on 
campus that works to 

create spontaneous art, such 
as spreading bubble wrap 
throughout the Diag.

>> SEE B SIDE on 1B

2

CAMPUS EVENTS & NOTES

Career Crawl 
- Gap Year 

WHAT: Learn about 
gap year opportunities 
including fellowships, 
research, volunteering, 
internships and 
jobs by talking to 
Michigan grads.
WHO: THE 
Career Center
WHEN: 12 p.m. 
to 1:30 p.m. 
WHERE: Pond Room 
- Michigan Union

A chemical and biological 
weapons expert and 
member of the Islamic 
State being held in U.S. 

custody in Iraq said militants 
plan to use mustard gas as 
a weapon, according to The 
New York Times. Sleiman 
Daoud al-Afari once worked 
for 
Sadaam 
Hussein’s 

Authority.

1

Reading and 
Book Signing

WHAT: Nina McConigley, 
author of “Cowboys and 
East Indians,” will read a 
selection from her fictional 
work and sign books.
WHO: Nina McConigley
WHEN: 5:30 p.m. to 6:30 
p.m.
WHERE: Museum of Art - 
Helmut Stern Auditorium

Kyle Odom, suspected 
of shooting a pastor 
in Idaho, went to the 
White House to deliver 

a manifesto, which admits to 
the plotting of the murder as 
a part of an alien conspiracy 
to control the human race, 
on Wednesday according 
to The Washington Post. 

3

Penny Stamps 
Speaker Series

WHAT: A talk given 
by the vice president of 
cognitive computing at 
IBM Research, who leads 
an international team 
creating the next generation 
of cognitive systems.
WHO: Guruduth Banavar
WHEN: 5:10 p.m. to 6 p.m.
WHERE: Michigan Theater

First 
Derivatives 
Coffee Chats

WHAT: Speak one-on-one 
with a representative of the 
First Derivatives recruiting 
team. Learn about working 
for a leading provider of 
products and consulting 
services.
WHO: The Career Center
WHEN: 9 a.m. to 4 p.m.
WHERE: The Career 
Center Office

Gossip Stoppers

WHAT: Learn how to 
create a positive workplace 
environment by decreasing 
negativity and gossip. 
Learn how to identify and 
address these issues and 
improve job satisfaction 
and productivity. This 
program has a fee of $179.
WHO: April Callis - 
Learning and Professional 
Development (LPD)
WHEN: 1 p.m. to 5 p.m. 
WHERE: Administrative 
Services Building

Careers for 
Ph.D.s

WHAT: Learn about the 
MBTI theory and career 
options outside of academia. 
Find a non-academic career 
that matches your personality. 
RSVP through Handshake.
WHO: Career Center
WHEN: 3:30 p.m. to 5 p.m. 
WHERE: Career Center 
- Program Room (3003)

Digital Music 
Ensemble

WHAT: Aided by the audience, 
composer and musician Judy 
Dunaway will perform her 
Balloon Symphony. She is 
known for electro/acoustic work 
with balloons.
WHO: Judy Dunaway
WHEN: 7 p.m.
WHERE: Earl V. Moore 
Building

Gifts of Art

WHAT: The Vocal Arts 
Ensemble of Ann Arbor 
will perform a program 
called “Rumor Has It,” 
consisting of songs about 
gossip. This will be a 
mixture of classical, 
musical theater and jazz 
music.
WHO: Vocal Arts 
Ensemble (VAE)
WHEN: 12:10 p.m. to 1 
p.m. 
WHERE: University 
Hospitals - Main Lobby 

Unlike 
adult 
with 
brain 

tumors, 
children 
cannot 

receive 
radiation 
therapy 

because children’s brains have 
a highly impermeable blood-
brain barrier, meaning most 
chemotherapeutic agents are 
not responsive.

Carl Koschmann, a cancer 

specialist at the UM Mott’s 
Children’s Hospital and the first 
author of the study, explained 
children with high-grade glioma 
are even more challenging to 
treat.

“Pediatric 
high-grade 

glioma remains very difficult 
to treat effectively, and most 
children will not survive beyond 
two years of receiving this 
diagnosis,” Koschmann said. 
“The difference is that some 
of the tools that work for other 
cancers, including surgery and 
radiation, are difficult to use on 
a child’s brain. Chemotherapy 
works for some brain tumors, but 
high-grade glioma is resistant to 
almost all chemotherapy.”

The 
inability 
to 
use 

chemotherapy has led to the 
exploration of several alternative 
methods of treatment, including 
DNA damaging drugs. 

DNA-damaging drugs have 

existed for many years and are 
used for various purposes in 
adult patients, but University 
researchers have found that, 
when used on the new model 
mice, they shrank the size of 
their brain tumors.

One-third of children with 

brain tumors have a mutation in 
the ATRX protein that already 
helps repair damage to the cells 
— Castro said by furthering that 
damage to the cells with the 
drugs, they were able to kill it all 
together.

“If you have bad mutations, 

your DNA is unstable, so you 
treat it with a drug that induces 
further damage, and the cell 
dies more readily, that means 
you are going to be able to treat 
these children in a better way,” 
he said.

Third-year medical student 

Flor Mendez worked on the 
research project, and said she 
thought the progress they have 
made will help future treatment.

“Our work on the role of 

ATRX mutations, prevalent in 
pediatric GBM, uncovered that 
ATRX deficient tumors have 
a defect in a mechanism of 
DNA repair which makes them 
more sensitive to therapies that 
induce DNA damage to destroy 
tumor cells,” she said. “This 
knowledge 
will 
help 
guide 

the development of improved 
therapies 
for 
patients 
with 

ATRX mutations.”

Other University researchers 

within the same lab have also 
been working to develop new 
treatment techniques through 
immunotherapy, 
which 
the 

mouse model can also be used 
for. That form of treatment 
trains the immune system to 
recognize and attack cancer 
cells, which Castro said is 
incredibly difficult due to the 
complex nature of cancer cells.

“Tumors have mechanisms 

by which they can hijack the 
immune 
system, 
they 
trick 

the immune system and they 
become kind of invisible so what 
you need to do is unmask it,” 
Castro said. “And you need to be 
able to allow the immune system 
to be able to see the tumor as an 
invader in a way as they would 

see a bacteria or a virus.”

The new mouse model 

allows for developments in 
immunotherapy 
because 

the model has a fully 
functioning 
immune 

system Castro said. Most 
models 
currently 
used 

for research take tumors 
from human patients to 
prepare cells for testing, 
but these cells are not 
compatible with animal 
models. 
Therefore, 

researchers 
cannot 
test 

immunotherapeutic 
strategies. 

Lowenstein said he finds 

immunotherapy appealing 
as a scientific avenue for 
treatments for a variety of 
reasons.

“The ability to harness 

the power of the immune 
system to treat cancer is a 
very attractive treatment 
modality 
for 
these 

devastating 
childhood 

brain cancers, as it could 
provide an effective, safe 
and non-invasive treatment 
strategy,” Lowenstein said.

AVA RANDA/Daily

The new Pure Barre location at 539 E. Liberty St. 

RESEARCH
From Page 1A

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