effect, allowing doctors to see
specific structural details.
Lewis, working under Daniel
Orringer, assistant professor of
neurological surgery, said the
development team currently uses
the SRS microscope to detect
proteins and lipids, two major
structural components of cells and
tissues. While tumor tissues look
similar to normal tissues to the
naked eye, they organize proteins
and lipids very differently at the
cellular level, allowing for easier
distinction between the two.
“That allows us to see the
architecture of the brain in vivid
detail that’s just not possible
with
traditional
microscopy
techniques,” Lewis said.
This
gives
doctors
a
potentially
faster
and
more
accurate
distinguishing
tool
than the method that’s currently
used, called the frozen-section
method. By allowing doctors
to
shorten
surgeries
and
confidently remove more of
a tumor, Lewis said chances
for relapse as well as for
complications of surgery could
be lessened.
Lewis said the typically used
frozen-section technique has a
couple of drawbacks.
“The problem is that it takes
a while — 30 to 45 minutes,” he
said. “And also it introduces a
lot of artifacts like ice crystals
that can mess with the accuracy
of the pathologist’s read. SRS is
done without labels and without
damaging the tissue. It’s done
on fresh tissue. You take it out,
mount it on a slide and image it
right there.”
While the SRS currently
takes about the same amount of
time as a frozen-section, Lewis
said optimizing the technology
could get imaging times down
to one second.
The microscope could also
help to improve the stereotactic
brain surgery technique, which
combines
3D
models
of
the
brain taken before surgery with
probes attached to the surgeons’
instruments
to
show
doctors
exactly where their tools are
during an operation.
“The problem with this is that
because the brain is soft and the
brain can swell, it can shift during
surgery,” Lewis said. “So, during
the course of an operation, you
can’t always tell where you are
relative to the preoperative MRI as
you are dissecting the tumor. And
that leads to inaccuracy.”
By identifying brain tissues
in real time, Lewis said the SRS
microscope could prevent these
inaccuracies.
The SRS microscope, which
is the first commercial version
in the world, has been used on
more than 60 patient brain tissue
samples since June. Until the
team finishes development and
procures FDA approval, however,
no surgeons will use it to make
clinical decisions.
Lewis
said
that
future
improvements to the microscope
and
imaging
methods,
such
as adapting the SRS to detect
molecules that build up specifically
in
cancer
cells,
could
have
enormous impacts on surgery.
“Essentially,
you
could
highlight tumor cells specifically,
which would be a tremendous
advance,” he said.
Next, the research team hopes
to develop a probe-like model
of the microscope that could
examine tissues while they are
still in the brain.
BRAIN TUMORS
From Page 1A
2A — Thursday, October 22, 2015
News
The Michigan Daily — michigandaily.com
THREE THINGS YOU
SHOULD KNOW TODAY
The Michigan Daily’s
arts staff explores Ann
Arbor’s Sunday Vintage
Market, which includes a host
of exhibits from local artists.
>>FOR MORE, SEE PG. 1B
2
CAMPUS EVENTS & NOTES
Opportunity
fair
WHAT: International
Opportunities Fair
presents student with
internships, volunteer and
teaching positions abroad.
WHO: Career Center
WHEN: Today from 2
p.m. to 6 p.m.
WHERE: Michigan
Union, 2nd Floor
Vintage Swing
performance
WHAT: The Royal
Garden Trio showcases
traditional jazz, show tunes
and gypsy-style swing.
WHO: Gifts of Art
WHEN: Today from
12:10 p.m. to 1 p.m.
WHERE: University
Hospitals, Floor 1 Lobby
Vice President Joe Biden
will not run for president
in 2016, The New York
Times reported. Biden said
during a press conference in
the Rose Garden Wednesday
that mourning for his son Beau
played a role in his decision to
stay out of the race.
1
EEB seminar
speaker series
WHAT: Associate Prof.
Jay Storz of Biological
Sciences at the University
of Nebraska lectures
on causes of parallel
molecular evolution.
WHO: Ecology and
Evolutionary Biology
WHEN: Today from 4 p.m.
to 5 p.m.
WHERE: Chemistry
Building, Room 1210
Randolph
Holder,
an
officer with the New
York Police Department,
died Tuesday night while
he was responding to reports of
gunshots, CNN reported. In the
past 11 months, Holder is the
fourth officer killed in the line
of duty.
3
‘Kisses to the
Children’
WHAT: A documentary
about Jewish community
in Greece based on
testimonies of Holocaust
survivors.
WHO: Modern Greek
Program
WHEN: Today from 7 p.m.
to 9 p.m.
WHERE: Chemistry, Room
1210
Visiting writer
Q&A
WHAT: Author Sarah
Shun-lien Bynum lectures
and takes questions about
her career.
WHO: School of Music,
Theatre & Dance
WHEN: Today from 2
p.m. to 3 p.m.
WHERE: Angell Hall,
Hopwood Room
TUESDAY:
Campus Voices
THURSDAY:
Twitter Talk
FRIDAY:
Photos of the Week
WEDNESDAY:
In Other Ivory Towers
MONDAY:
This Week in History
Delegation
workshop
WHAT: Learn effective
delegation to developing
leadership skills and
effective communication.
WHO: Learning and
Professional Development
WHEN: Today from
8:30 a.m. to 4:30 p.m.
WHERE: Administrative
Services Building,
Room 2030
Penny Stamps
lecture
WHAT: 2014 ArtPrize
winner Sonya Clark talks
race, identity and heritage
regarding her existing and
new work.
WHO: Penny Stamps
School of Art & Design
WHEN: Today from 5:10
p.m. to 6 p.m.
WHERE: Michigan
Theater
Uniersity Health System
spends Back to the Future Day
praising their modern tech.
“We might not have hoverboards,
but the med tech we use in this
1986 building would amaze Mc-
Fly. #BacktotheFutureDay.”
— @UMHealthSystem
“[The support has] been overwhelming.
It speaks a lot to the Michigan Com-
munity about how supportive they’ve
been.” - Blake O’Neill #GoBlue
—@umichfootball
Michigan Football rallies around player
Blake O’Neill in the wake of the MSU
game.
Each week, “Twitter Talk”
is a forum to print tweets
that are fun, informative,
breaking or newsworthy,
with an angle on the
University, Ann Arbor and
the state. All tweets have
been edited for accurate
spelling and grammar.
Gov. Rick Snyder, an alum, wore a
green tie after losing a bet over
Saturday’s game against MSU.
“No matter who you were
cheering for this weekend,
now let’s all root to beat Ohio
State. #GoBlue #GoGreen.”
- @onetoughnerd
FOLLOW US!
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DUNK FOR CHARITY
MARINA ROSS/Daily
LSA sophomore Michael Roberts participates in the
Sigma Chi philanthropic dunk tank to raise money for the
Huntsman Cancer Institute on Wednesday.
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Internship
workshop
WHAT: Gain the skills to
land the internship of your
dreams.
WHO: The Career Center
WHEN: Today from 5:30
p.m to 6:30 p.m.
WHERE: The Career
Center, Program Room 3003
‘U’ in D.C. program
celebrates 10th year
Students take classes
and intern while
on Michigan in
Washington program
By EMMA KINERY
Daily Staff Reporter
The Michigan in Washington
program,
through
which
University students temporarily
trade life in Ann Arbor to work
in the nation’s capital, will turn
a decade old this week. Since
2005, the program has given 45
to 50 students per semester the
opportunity to spend either the
fall or winter in Washington,
D.C.
“The MIW program was
created to provide students
with an opportunity to live,
work and study in Washington,
D.C.,” said Edie Goldenberg, a
professor of public policy and
political science who was the
founding director of the MIW
program. “The major idea is
for undergraduates from any
major at UM to use what they
learn
in
their
internships
and what they learn in class
to complement each other in
meaningful ways.”
On Friday, the program will
hold a banquet at the National
Press Club in D.C. featuring
pre-recorded
speeches
from
University
President
Mark
Schlissel, Michigan Gov. Rick
Snyder, as well as a live stream
speech from LSA Dean Andrew
Martin. Rep. David Trott (D–
Birmingham) will keynote the
celebration.
The
program
experience
begins before students leave
campus since they are required
to take a preparatory course the
semester before leaving for the
capital. Once in Washington,
participating
students
are
paired with a University alumni
mentor and are required to
find an internship and write
a research paper, in addition
to taking classes — a feat
Goldenberg says isn’t easy.
“
MIW
is
academically
rigorous,”
Goldenberg
said.
“Every student completes 12-15
UM credits, nine of which are
required and the others elective.
The courses are designed to
take advantage of being in D.C.
rather than merely to duplicate
what’s available on campus.
”
Though more than half of the
2013-2014 class was comprised
of political science majors, the
program accepts students from
all fields of study, and students
arrange to get credit for their
major through their internship
and research paper.
Students are also encouraged
to find an internship that best
suits their interests. Members
of last year’s class interned
at
organizations
such
as
congressional offices, the U.S.
Department of State, the Sierra
Club, NBC’s “Meet the Press,”
the Mexican Embassy and the
John F. Kennedy Center for the
Performing Arts.
After
10
years
of
the
program, the alumni base has
amassed 460 individuals in all
lines of work around the world.
For many, their experience in
Washington has opened up
doors to future career options.
“All of our alums are notable,”
Goldenberg said. “MIW alums
have won writing prizes for
their research papers. Two have
been chosen as commencement
speakers. Roughly 40 have
graduated and been employed
in
the
Washington,
D.C.
area. Many others have been
admitted to graduate schools
of their choice. Several have
published their work and others
have started charitable efforts.”
Students currently studying
in D.C. already feeling the
benefits of the program. LSA
senior Whitney Swart, who is
interning at an organization
that provides legal and social
services to immigrants, said
the opportunity has given her
a better handle on her future
goals.
“In
the
Michigan
in
Washington Program, I have
had the opportunity to make
important connections, pursue
my passions and fall in love
with a new city,” Swart said. “It
wasn’t until I lived and worked
in D.C. that I truly understood
my goals and found myself.”
LSA junior Evan Viau, an
intern for the Truman National
Security Project, said his time
in D.C. has helped him find his
calling.
“My
time
in
MIW
has
been instrumental in refining
my
post-graduate
career
goals
and
allowing
me
to
grow both intellectually and
professionally,” he said. “I have
had substantive opportunities
to work with experts in my issue
areas to research, develop, and
advocate for national security
policies that address the new
challenges of the 21st century;
an
opportunity
I
probably
wouldn’t have had if I didn’t
spend a semester in the District
through this program.”
Viau said the work isn’t easy,
either.
“It’s certainly a challenging
environment—
being
surrounded by some of the
best and brightest around the
country— but it’s comforting
to see the impact of my hard
work daily,” he said. “I applied
to the program to find purpose
and support, and I’ve definitely
found it.”
@MICHIGANDAILY
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