2A - Wednesday, January15, 2014 The Michigan Daily - michigandaily.com iEht filgan DAMl 420 Maynard St. Ann Arbor, MI 48109-1327 www.michigandaily.com PETER SHAHIN KIRBY VOIGTMAN Editor in Chief Business Manager 734-415-4115 ext. 1251 734-41a-4115 ext. 1241 pjshahio@michigandaily.com kvoigtman@michigaodaily.com CAMF M RDI Furman U. recieves $1M gift Furman University in Green- ville, South Carolina, received $1 million through the Duke Endowment, the Greenville News reported. The grant went to support the work of the Riley Institute, the public policy orga- nization devoted to improving the social and economic condi- tions of the state. The Duke Endowment, a pri- vate foundation established by philanthropist James B. Duke to support the people of North and South Carolina, rewarded the Riley Institute for its focus on "education, diversity and critical issues impacting the state," The fund also aimsto strength- en the pubhlic policy programs that benefit Furman students, faculty and residents across the state in the areas of public edu- cation, economic development, leadership, diversity and other issues. Police investigate bomb hoax at Texas State University The Texas State University- San Marcos campus received a bomb threatcearly Tuesday morn- ing that was later found to be a hoax, KXXAN News reported. The Texas State University Police investigated the campus throughout the morning, initially closing downa residence hall and surrounding areas, but found no sign of explosives. Police arrested suspect Clay- ton Garland Warren, a 24-year- old man who is accused of issuing the bomb threat. He is currently in custody at Hays County Jail and faces three criminal charges, according to Texas State Univer- sity spokesman Jayme Blaschke. Warren's vehicle contained two suspicious devices, but were later declared not explosive. Blaschke said the fakebombs were designed as real explosives and criminal intent remains unknown. Students living in College Inn, a large co-ed dorm on campus with 300 residents, were forced to spend more than four hours at the student recreation center while police searched the area. -ALLANAAHKTAR Newsroom 734-418-411s opt.3 Corrections corrections@michigandaily.com Arts Section EioilPt arts@michigandaily.com Sports Section sports@michigandaily.com Display Sales d a ilyd isp lay@gm ail. com Online Sales onlineads@michigandaily.comn News Tips news@michigandaily.com Letterstothe Editor tothedaily@michigandaily.com opinion mciandaly.com Photography Section photo@michigandaily.com . Classified Sales classi fied@m ichigandaily.com Finance finance@michigandaily.com AMES COLLtR/Laily LSA freshman Lester Lee plays table teSis during Winterfest Tuesday afternoon. CRIME NOTES CAMPUS EVENTS & NOTES Slipping and Golf cart sliding getaway WHERE: Couzens Hall WHEN: Monday at about 10:10 a.m. WHAT: A Student was taken to the University Emergency Department after falling, University police reported. WHERE: Stadium Gate 1 WHEN: Monday at 12:15 p.m. WHAT: A rented golf cart was stolen from the loading dock area at about 3:00 p.m., University Police reported. There are currently no suspects. Eco-friendly Where's the thievery beef? Saxophone Lecture on performance 'being nuclear' WHAT: Saxophonist, Uni- WHAT: University profes- versity alum and member of sors discuss what it means the band Bon Iver will give to be "nuclear" - whether it an emotionally gripping be a state or an object. preformance. WHO: Gabrielle Hecht and WHO: Colin Stetson Elizabeth Roberts WHEN: 7:30 p.m. WHEN: 5:30 - 7:00 p.m. WHERE: Walgreen Drama WHERE: Harlan Hatcher Center, Arthur Miller Graduate Library, Room 100 Theatre CORRECTIONS The Deadly A previous version of the article "University Provost Gentlemen defines Shared Services task plans"printed Tuesday, performance Jan.15 misstated the name of the overall service reform WHAT: The group will play plan. It is the Administra- a classical set with a modern tive Services Transforma- twist from their new album, tion, not the Administration "Roll Me, Tumble Me." Services Transition. WHO: The Deadly Gentlemen 0 Please report any error WHEN: 8:00 p.m. in the Daily to correc- WHERE: The Ark, 316S. tions@michigandaily.com. In true Walter White fashion, blue meth is being sold in New Mexi- co and the greater Four Cor- ners region, the Huffington Post reported. The drugs have been making people sick, reportedly because of the chemicals to make itblue. Is faith fading on campus? Data reveals fewer students are identifying with religion at the University. The Statement delves into reasons behind the decline. g FOR MORE, SEE THE STATEMENT, A Chinese commer- cial for Rio Burgundy Grape Mint caused controversy when the pro- tagonist of the ad is so over- come by the powerful flavor of the mint he fails to notice his stuffed purple llama lick- ing his chest, ABC reported. 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Sus"ritins for'flltr, msating inSeemerva U.S asire $110 Winter term (January through April) is $115s yearlong (September through April) is $195. University affiliates aresubjecttoareducedsubscriptionrae. n campussubsriptonsforfaltermare$5.Subscriptionsmust be prepaid. The Michigan Daily is a member of The Associated Press and The Associated Collegiate Press. WHERE: 900 Block, S. University Ave. WHEN: Thursday at 12:50 a.m. WHAT: Abike was stolen from a rack in front of Sha- piro Undergraduate Library the previous night, Univer- sity Police reported. There are currently no suspects. WHERE: University Hos- pital WHEN: Tuesday at about 2:20 a.m. WHAT: A subject stole food from the cafeteria without paying and left the building, University Police reported. Subject was 34 years old and arrested soon after. MORE ONLINE Love Crime Notes? Get morefonline at michigandaily.com/blogs/The Wire 'U' protein research could lead to better drug treatment Professors study how water affects molecular functions By TOM MCBRIEN Daily StaffReporter Much like students at a club on a Saturday night, proteins can act differently when crowded together than when they are more spread out. A team of University research- ers is at the forefront of studying this phenomenon as they focus on how water acts between proteins surrounded by bulky molecules, known as crowded proteins. The research may enable scientists to better understand how proteins work, which can lead to improved drug treatments in the future. The researchers' paper, "Crowding Induced Collective Hydration of Biological Macro- molecules over Extended Dis- tances," was recently published in the Journal of the American Chemical Society and is acces- sible online. Proteins called enzymes carry out many crucial chemical reac- tions in the body. They are often studied in terms of the molecules they bind to carry out these life- sustaining reactions. However, an aspect of protein chemistry that has been overlooked is that they are almost always acting in crowded, watery environments. Assistant Chemistry Prof. Kevin Kubarych said crowded environments can alter the way in which we view protein activity. "When you stuff people together, like kids at a club - as the walls of the club start to get closer and closer together, the music might be the same and the dancing might be similar, but the way that the actual motion of people works through the club is going to change. If you want to go from here to there, you have to mess with 25 people on your way,"Kubarych said. In the researchers' model, crowding of proteins causes the water surrounding them to slow down. In keeping with Kubarych's example, they have less room to move in the club. As a result, the proteins, which normally fluctuate in shape, also begin to slow down. "If the solute is just protein, that means that proteins are indi- rectly sharing information with each other through this attribute of water," Kubarych said. The information could have important pharmaceutical and medical implications. Each pro- tein has very specific molecules called substrates to which it binds and on which it performs certain actions. For example, the protein salivary amylase, present in human saliva, starts breaking food apart as it's eaten. Dr. Margaret R. Gyetko, senior associate dean for Faculty and Faculty Development at University Medical School, speaks about promotions and tenure at the Towsley Center Tuesday. Medical School hosts town halls to talk pro-motion I ,-S Many important drugs work by closely mimicking substrates that proteins would normally bind to, keeping them from bind- ing to their normal substrates and thus causing some change in the body. Exactly how well proteins bind to their substrates and how quick- 8 ly this happens depends on a host of factors, one of which may have to do with the state of the water surroundingthe protein. Kubarych said crowding could affect water molecules, which then affects unbound proteins' fluctua- tions, changing the way in which theybind to their substrates. Knowing more about how pro- teins respond to crowding could illuminate more about the speed at which they bind to certain drugs, which can be the differ- ence between life and death in some cases. "Waiting for one or two days 7 for your drug to take effect - that's only a factor of two in chemistry but can make a huge difference for a sick person," Kubarych said. Meetings address issues from dean's annual speech By CAROLINE BARON For the Daily Even doctors need a reminder that in order to succeed, you have to ask for what you want. Margaret Gyetko, the senior associate dean for faculty and faculty development at the Uni- versity Medical School, held a seminar Tuesday to address the ways that the Medical School's faculty members can best earn promotions and tenure. The meeting was part of a series hostedby the school's dean, James Woolliscroft, as a way to promote interaction between the Medical School community and its leadership. The series of town halls supplement issues raised in Woolliscroft's State of the School presentation, which was held in September. Thiseventwas Gyetko'sseventh seminar on the topic. The idea for the series first emerged after she received large numbers of poorly prepared promotion packages from the school's faculty. "I had been getting a lot of applications where it was very clear to me that (the applicants) were smart and talented, but they didn't know how to plan ahead in a waybest conducive to achieving promotions," Gyetko said. "You know, we have an amazing and brilliant faculty, but the only way to win the game is to know the rules, and know if you're ahead or behind." The seminar focused on what aspects are most valued and scru- tinized by the school's leadership when making decisions about promotions of faculty members. Gyetko's talk focused on differ- ent ways that faculty could pre- pare their promotion packages to make themselves mostappealing, as well as the types of goals they try to achieve that would make them ideal candidates for a pro- motion in the future. Gyetko added that the timeline to obtain a promotion is long and cannot be rushed in the five years before a faculty member requests career advancement. She also said it's important for faculty to understand that moving up is natural and that they should strive for it. During the seminar, Gyetko said she recommends cultivating relationships with people in the same field, following through on promises and ensuring prepared- ness for the added responsibili- ties that accompany a promotion. She also drew attention to a pro- gram available at the Medical School to help facultyassess their readiness before beginning to prepare promotion packages. The entire lecture is available for viewing on the UMHS website. JOIN THE DAILY MASS MEETINGS: THURSDAY, JAN.16 & MONDAY JAN. 20 7:00 P.M. AT 420 MAYNARD STREET Y