The Michigan Daily - michigandaily.com Thursday, October 3, 2013 - 5A ALS From Page 1A relatively new strain of human embryonic stem cells developed at the University through part- nerships with the National Insti- tutes of Health. She referenced the work of Physiology Prof. Gary Smith at MStem Cell Laboratories - the University's stem cell insti- tution - as a crucial component to the development of the treatment. "What we've done here at the University of Michigan ... is make embryonic stem cell lines, which are now being used for under- standing disease course as well as for treatment," Feldman said. Stem cells have the potential to aid in the treatment of not only ALS, but awide range of debilitat- ing and life-threatening diseases, including Parkinson's disease, Alzheimer's disease and multiple sclerosis, Feldman said. "I know that the potential of human embryonic stem cells is really in its infancy," Feldman said. "As we engage in under- standing of what stem cells do, we will really then begin to more fully understand their complete potential. I really don't think we're even at the tip of the ice- berg." Although the results from the trials are still preliminary, Feld- man said four of 15 patients tested in Phase I experienced a "stable or improved disease course." Prior to human studies, the research team demonstrated the capability of this treatment to slow the pro- gression of symptoms in rats with the disease. "Stem cells placed into the spi- nal cord of these rat models of ALS caused the large motor neu- rons to survive," Feldman said. "And also actually allowed the rats to have continued function and not to die as quickly from their disease. We're very excited about that." Prior to 2008, Feldman spent 10 years investigating ALS treat- ments in California, while stem- cell research was still illegal in the state of Michigan. After the passage of the Michigan Stem Cell Amendment, which loosened restrictions on stem-cellresearch, Feldman moved her research back to the University and has contin- ued here ever since. Although the research - in particular, embryonic stem-cell research - is still controversial in some areas of the country, Feld- man said the research has the potential to impact the lives of people suffering from degenera- tive diseases. "I am more pro-life than any- one because what I do is take embryos that were previously lit- erally discarded down a garbage disposal, and I take those embry- os and we create new embryonic stem cell lines," Feldman said. "And I think you can see today the hope that these new stem-cell lines can offer for what are really fairly devastating diseases." After studying ALS at the Uni- versity for almost 25 years, Feld- man said she is equally interested in understanding the disease as well as the treatment. Martin Fischhoff, managing director of the Taubman Institute, said this focus on "translational research" is important to the future of fed- erally funded research projects. "There's been a disconnect between the research being done in the laboratories and the development of new treatments for patients," Fischhoff said. "We're doing important research, but there hasn't been the same emphasis of bringing them to patients through new treatments and new therapies, which is what we're tryingto do at the Taubman Institute and I think throughout the University." "To do this kind of pioneering stem cell researchhere at the Uni- versity of Michigan is something everybody in the state should be proud of," he said. - Brie Winnega contributed reporting. RENOVATIONS From Page 1A will invite a variety of foreign fla- vors provided by local Ann Arbor vendors; and an expanded salad and soup bar will offer grab-n-go and personalized options. Keith Soster, food service director for the University Unions, currently heads opera- tions at the Commons Cafe and has played a large role in the ren- ovation plans. "The nice thing about these four individual restaurant-type con- and individual study over longer cepts is the stations are designed periods of time. to be versatile," Soster said. "So "That whole space will lend that as the trends or needs or itself to great opportunities for desires of the students change, we collaborations for students," Sos- can help modify the menu." ter said. The caf6's cafeteria-like dining Mitchell Field will be renovated area will also get a face-lift. Tall alongside the cafe with a focus on stools, booths and soft lounge improving lighting, constructing seating will be added to the stan- a support building for Rec Sports dard cafeteria tables and chairs. staff and creating a student space An additional 60 to 70 seats for intramural and club teams. will be fitted in the dining area The total project cost to reno- to accommodate an influx of stu- vate Mitchell Field, the three dent traffic and create a more recreational sports facilities, conducive environment for group Pierpont Commons and the Michigan Union is estimated at $174 million. A $65-per-semester student fee will be implemented in fall 2014 to pay forthe projects. Nearly 22 percent of the revenue from the student fee will be con- verted into financial aid. A poll conducted by Building a Better Michiganpollin2012found broad support for the fee, which was approved by the University's Board of Regents in April. "This (fee) is not a minority opinion, and the University is offer- ingfinancialhelptothe people who are going to need it," Mirante said. SOLAR From Page1A year team member, is a part of the leadership committee where he oversees timelines, budgets and recruiting. "I definitely fell in love with Solar Car because of what a real- world project it is," Kauney said. "It's inherently creative and mul- tidisciplinary, and we have all types of engineers and even LSA and Ross kids that we're able to bring in collaborate with, so there's always something going on and there's always something to learn from someone." Kauney echoed his team- mates' sentiments about win- ning, but says this week's race is especially important to him because he's been working on the car's design from the beginning. "When you're working 20 EQUAL From Page1A sex discrimination case against Goodyear, but the ruling was overturned on an appeal. "I was devastated, humiliated and could not let it go," Ledbet- ter said. Over the next eight years, Led- better's case made it to the U.S. Supreme Court, where the jus- tices ruled in favor of Goodyear, saying that she should have filed a case within 180 days of her first unequal paycheck, even though Ledbetter was unaware of the discrepancy for nearly 20 years.. "I could not let a major corpo- ration (take advantage of) me and hours a week on this one proj- ect all year, it's definitely a lot of work, but you're all doing it together," Kauney said. "There's definitely camaraderie that comes into it, and you want to do your best and see the car do its best for the University, for your- self, and for everyone else." While dedication and high rank- ings may have proven to be staples of the Solar Car Team, Kauney said the onethingthathas changed this year is the car's name. "Every other car we've designed has had the letters UM somewhere in it, but we decided to switch it up this year and go with something completely dif- ferent, deciding on 'Generation,' " he said. "It's a tribute to every- thing we're a part of, the 1,200 alumni of the group, and the 12 car cycles." Engineering sophomore Con- nor O'Brien, a second-year mem- my family," she said. In 2009, Ledbetter made national news again. This time her name became the symbol of President Barack Obama's first piece of legislation signed as president: the Lilly Ledbetter Fair Pay Act. On average, women make 77 cents to every dollar men earn, and the discrepancy is even worse for women of color. Under the act, more time is allowed for lawsuits to be filed for discrimi- natory wage practices. Since then, Ledbetter has toured the nation speaking about gender equality. "(Inequality) is going on'every day - as I speak tonight - in this country, and that's why I still do ber, explained that after the race, the team will have time to re- group and experiment, which he enjoys. "With everything already done for Sunday's race, we've kind of surpassed the climax of the season and will have time to restructure and rebuild as a team, which I'm really looking forward to," O'Brien said. "Now we'll have time to try out differ- ent things and reorganize our workspace, which will be nice." As an engineer, O'Brien said the skills he has learned on the team are very different from those he learns in the classroom. "The things we learn at Solar Car don't reinforce the things I'm learning in my class- es because they're different aspects of engineering, but I like that it broadens my scope and skill set," he said. He added that the most this today," Ledbetter said. "This country is better than this, and we need to correct these prob- lems. We have to get some laws to protect the people." LSA senior Brianna Hender- son said she attended the lecture because she had heard many dif- ferent perspectives on the Equal Pay Act and wanted to hear from Ledbetter herself. Ledbetter was invited to speak by the Department of Women's Studies and the Institute for Research on Women and Gender for their annual Vivian R. Shaw lecture, part of a series highlight- ing issues affecting women or gender. An open question-and- answer section preceded her speech. LSA senior Elizabeth important part of racing strat- egy is to "expect the unex- pected." He recalled a 2011 race where the course involved driving through unanticipated smoke due to brush fires, which resulted in an emergency stop and threw off their race strategy completely. "The nicest part about this year is how there haven't been any major engineering problems with the car," O'Brien said. For O'Brien, Solar Car is more about being a part of something big. "Being a part of our team means you're a necessary part of one of the best engineering projects in the world," he said. "We're kind of the poster child of the College of Engineering, and we get a lot of exposure, and we take a lot of pride and caution in making sure that everything we do is deserving of that title." Schapiro voiced her concerns as a woman soon entering the work- force. "I'm shocked by the time- frame of your case," she said. "I thought we'd be talking about the 50s and 60s. As a senior entering the workforce next year, I'm now concerned about my salary." A signing of Ledbetter's book "Grace and Grit: My Fight for Equal Pay and Fairness at Good- year and Beyond" followed. "This has been a journey, and it has been very rewarding," Led- better said. "And no, I do not buy Goodyear tires." - Daily StafftReportg Jennifer Calfas contributed to this report. Pressure builds for quick fix to health exchange issues (AP) - The pressure is on for the federal government and states running their own health insurance exchanges to get the systems up and running after overloaded websites and jammed phone lines frustrated consum- ers for a second day as they tried to sign up for coverage using the new marketplaces. In some ways, the delays that persisted Wednesday were good news for President Barack Obama and supporters of his signature domestic policy achievement because the holdups showed what appeared to be exceptional- ly high interest in the overhauled insurance system. But if the glitches aren't fixed quickly, they could dampen enthusiasm for the law at the same time Republicans are using it as a rallying cry to keep most of the federal govern- ment closed. "It was worse today than it was yesterday," Denise Rathman of Des Moines said after she tried for a second day to log onto the Iowa site. Rathman has insurance through Dec. 31 but said she is eager to sign up for a policy because of her psoriatic arthri- tis, which has caused her to be denied insurance in the past. David Berge, a pastor with two young children in Shorev- iew, Minn., tried unsuccessfully at least 10 times to create an online account on the state-run site MNsure. His high-deductible plan expires at the end of the year. "I'm anxious to see what the insurance is going to look like for my family at the beginning of the year," Berge said. "That's a big unknown right now. I want to fig- ure that out as soon as possible so we can begin planning." In California, home to 15 per- cent of the nation's uninsured, officials pulled the enrollment portion of the Covered California site down overnight for emergen- 0 cy upgrades. It was restored mid- morning Wednesday, and 7,770 people had started applications by then, spokesman Roy Kennedy said. California is one of a hand- ful of mostly Democratic states that opted to set up their own exchanges rather than let the fed- eral government do it for them. In the 36 states being operated by the federal Department of Health and Human Services, consumer patience was still being tested. Agency spokeswoman Joanne Peters said many Americans suc- cessfully enrolled on the first day, but she declined to put a number on it. She said the delays were due to "overwhelming interest" and high volume. It's not as if nobody warned them. Just three months ago, the congressional Government Accountability Office said a smooth and timely rollout could not be guaranteed because the online system was still getting finishing touches and had not been fully tested. The Obama administration shrugged off the evaluation. The bumpy debut has the hall- marks of a technology project that may have rushed to meet the Oct. 1 deadline, said Bill Curtis, chief scientist at CAST, a soft- ware quality analysis firm, and director of the Consortium for IT Software Quality, which develops standards. "When you are in a rush, you typically make a lot of mistakes and you don't have time to test them all out," he said. High volume can also expose software flaws that were not detected in testing, Curtis said, like the recurring problem con- sumers encountered trying to set up accounts on the federal site. Drop-down menus that were sup- posed to provide security ques- tions did not work. The department issued sur- vival tips for aggravated con- sumers after 4.7 million unique visitors logged in to the health- care.gov website on Tuesday. As new health insurance markets went live around the country, the federal call center also received 190,000 calls. In suburban Cleveland, Sharon Schorr finally gave up on the fed- eral exchange website after eight hours of failed clicks. CANDIDATES From Page 1A tem. However, over the next 10 months,the University Board of Regents will be tasked with choosing whether to once again seek a candidate from outside the University or turn within the boundaries of its campuses. The advisory committee in charge of short-listing presi- dential candidates , recently released a Presidential Profile detailing their expectations. In an e-mail interview, Regent Katherine White (D), the vice chair of the board and act- ing spokeswoman during the search process, wrote that each candidate, regardless of prior affiliation with the University, would bring "something unique to the equation" and be judged based on the profile. "All candidates will be evalu- ated on their own merit, whether theyare internal or external," she wrote in an e-mail interview. "It is difficult to generalize about pros and cons based solely on whether a candidate is internal or external." E. Royster Harper, vice presi- dent for student affairs, said in a September interview that some of the internal issues she believed the upcoming president would be faced with include keeping college affordable, maintaining a balance between academic and athletic excel- lence, and improving diversity and inclusion. "I don't know if it'll be a chal- lenge, but we certainly want a president that understands the history of this place and the stu- dents' role in it," Harper said. Michael Bastedo, an associate professor of education, said he believed that an internal presi- dent had the advantage of need- ingless time to build connections within the University. "I think we can learn that hir- ing someone externally doesn't mean they make a bad president," Bastedo said. "Even though she was hired externally, now the perception of President Coleman is she's a very Michigan person - not somebody that wants to just act autocratically." By July 2014, the regents' decision to choose a president from within the University will depend on their valuation of lead- ership qualities. Matt Chingos, a fellow in the Brookings Institu- tion's Brown Center on Educa- tion Policy, said although having a top University administrator step up to the presidency would be a more "natural transition," someone from the outside would be more likely to bring an out-of- the-box perspective to the insti- tution. The solution may be to choose someone who had held a position in the University for only a short period of time, Bellman said. Coleman said in a September interview that her experience serving as a president of the Uni- versity of Iowa prepared her to serve the same at another Big Ten university. It took a few years, she said, but over time she believed she was able to learn the ropes of the University. "It's like drinking from a fire hose," Coleman added. "You have to just learn, learn, learn and lis- ten intently, but itcan be the most exhilarating." - Daily Staff Reporter Jennifer Calfas contributed reporting. A