10 - The Michigan Daily - Wednesday, March 27, 2002
ARTS-
4
Wu-tang still dangerous after 10 years
By David Mosse
Daily Arts Writer
tate a certain other famous Motown
star. Not to be outdone, a heavy
metal group called Tri-Tek graced
the stage with their nauseating
brand of "music."
When the first two members of
Almost a decade after they
changed the face of hip-hop with
their groundbreaking debut, the Wu-
Tang Clan continue to
light up audiences
throughout the country.
On Sunday night,
Shaolin's heralded
swordsmen brought
the ruckus to the State
Theater in Detroit and
thrilled the crowd with
old and new material.
WU-TANG CLAN
State Theater, Detroit
Sunday, March 24
the Wu finally
arrived, GZA and
Ghostfacekillah, the
energetic crowd
exploded. Arguably;
no other rap group
has achieved such
won, followed by, perhaps the man
most responsible for the success of
the group, RZA. The four alternat-
ed between performing songs from
their various solo albums and their
joint LP's, including the spine-tin-
gling "Cream."
One member missing-in-action
was Russel Jones, a.k.a. Ol'Dirty
Bastard, who remains locked up in
a federal prison since his July
arrest, following his conviction on
cocaine possession conviction.
Jones was sentenced last April to
two to four years in prison. This
did not stop the crowd from chanti-
ng the initials O.D.B several times
throughout concert, most notice-
ably after the group performed his
hit song, "Shimmy Shimmy Ya"
The evening's most electric
moment came when Method Man
burst onto the stage to the beat of
his classic anthem "Release Yo
Delf." The group's most charismat-
ic star proceeded to rock the State
Theatre with performances of
"M.E.T.H.O.D Man," "Bring the
Pain," and the Grammy award win-
ning, "You're All I Need."
After treating the crowd to a few
more classic numbers from their
extensive catalog, including "Wu-
Tang Clan Ain't Nuthing Ta F'Wit"
and "Reunited," the crew got down
to some business, promoting their
latest release, Iron Flag.
Unfortunately, this only served
to illustrate that the Wu-Tang Clan
have lost some of their edge in
recent years. The selection of
songs from their new album, high-
lighted by the current single "Uzi
(Pinky Ring)" and "Rules"-- a
violent message to the perpetrators
of September 11th - failed to
{
I
a blend of
Their appearance came not a
minute-too-soon after fans were
forced to sit through two horren-
dous opening acts. First to bore the
crowd was a quartet of local rap-
pers, including a blonde-haired
white male trying his best to imi-
mass appeal as the
Wu-Tang Clan. Since the release of
Enter the 36 Chambers in 1993,
their rambunctious brand of hip-
hop has elevated them to an
almost-mythical status.
As the concert ensued, different
Clan members began to emerge to
the delight of the audience. Third
to make his appearance was Raek-
The Wu, keeping it real every second they're not blowing stuff up.
Courtesy of BMG/RCA
move the audience in the same
manner as their old material. RZA
also performed his new single
"Brooklyn. Babies" from his latest
release, "Digital Bullet."
Nevertheless, the presence of all
mi"T "
Contraceptive Injection g '
control y)ou -thin-k a~ou~t just +x- a year
medroxyprogesterone acetate injectable suspension
DEPO-PROVERA Contraceptive Injection
(medroxyprogesterone acetate injectable suspension, USP)
This product is intended to prevent pregnancy. It does not protect against HIV
infection (AIDS) and other sexually transmitted diseases.
What is DEPO-PROVERA Contraceptive Injection?
DEPO-PROVERA Contraceptive injection is a form of birth control that is given as an
intramuscular injection (a shot) in the buttock or upper arm once every 3 months (13 weeks). To
continue your contraceptive protection, you must return for your next injection promptly at the
end of 3 months (13 weeks). DEPO-PROVFRA contains medroxyprogesterone acetate, a
chemical similar to (but not the same as) the natural hormone progesterone which is produced
by your ovaries during the second half of your menstrual cycle. DEPO-PROVERA acts by
preventing your egg cells from ripening. If an egg is net released from the ovaries during your
menstrual cycle, it cannot become fertilized by sperm and result in pregnancy DEPO-PROVERA
also causes changes in the lining of your uterus that make it less likely for pregnancy to occur
How effective is DEPO-PROVIRA Contraceptive Injection?
The efficacy of DEPO-PROVERA Contraceptive Injection depends on folowing the
recommended dosage schedule exactly (see "How often do I get my shot of DEPO-PROVERA
Contraceptive Injection?"). To make sure you are ,not pregnant when you first get
DEPO-PROVERA Contraceptive Injection, your first injection must be given ONLY during
the first 5 days of a normal menstrual period: ONLY within the first 5 days after childbirth if not
breast-feeding; and, if exclusively breast-feeding, ONLY at the sixth week after childbirth. It is a
long-term 'injectable contraceptive when administered at 3-month (13-week) intervals.
DEPO-PROVERA Contraceptive Injection is over 99% effective, making it one of the most reliable
methods of birth control available. This means that the average annual pregnancy rate is less than
one for every 100 women who use DEPO-PROVERA. The effectiveness of most contraceptive
methods depends in part on how reliably each woman uses the method. The effectiveness of
DEPO-PROVERA depends only on the patient retuming every 3 months (13 weeks) for her next
injection. Your health-care provider will help you compare DEPO-PROVERA with other
contraceptive methods and give you the information you need in order to decide which
contraceptive method is the right choice for you.
The following table shows-the percent of women who got pregnant while using different kinds of
contraceptive methods. It gives both the lowest expected rate of pregnancy (the rate expected
in women who use each method exactly as it should be used) and the typical rate of pregnancy
(which includes women who became pregnant because they forgot to use their birth control or
because they did not follow the directions exactly).
Percent of Women Experiencing an Accidental Pregnancy
in the First Year of Continuous Use
Lowest
Method Expected Typical
DEPoPROVERA C.3I 0.3
Implants (Norlant)_ 02' 02.
Female stermaOin 0.2 0.4 _
Male sterinaion C 0.15
Oral contraceptive (p5) 3
Combined 0
Progestogen only 0-
UD 3
Progestasert 2.0
Cope-T-380A - - - -
Condom (without spermicide) 1 I2
Diaphragm (with spermicide) _ 6____
Cervical cap 8
Withdrawal 4 -I8
Periodic abstience 9-_ - - I-320
Spermcde alone s-21
vaginal Sponge
used before childbirth 6 18
used after childbirth 985-
No method li 5
Source: Trussell et al. Obstet Gynecot 1990:76:558 567.
*From Norplant' package insert.
Who should not use DEPO-PROVERA Contraceptive Injection?
Not all women should use DEPO-PROVFRA. You should not use DEPO-PROVERA if you have
any of the following conditions:
" f you think you might be pregnant
" if you have any vaginal bleeding without a known reason
the Clan's prominent members
(minus O'l Dirty Bastard) together
on stage were a welcomed sight for
Wu-Tang fans amid all the rumors
of dissension amongst the group in
the past year and speculation of an
impending break-up. While such
rumors were already squelched by
their appearance at the Source
Awards and the release of a new
album, this latest tour serves as
further proof of their solidarity.
As the night drew to a close and
the various group members
thanked the audience, Raekwon
remarked, "It's been 10 years and
we're still here. Not many groups
can say that.", With the passion and
energy they displayed at the State
Theater, the Wu looks poised to
continue on for another 10 years.
Yet, they will be hard pressed to
duplicate the remarkable success
they have already enjoyed.
- if you have had cancer of the breast
- if you have had a stroke
- if you have or have had blood clots (phlebitis) in your legs
- if you have problems with your liver or liver disease
" if you are allergic to DEPO-PROVERA (medroxyprogesterone acetate or any of its other
ingredients).
What other things should I consider before using DEPO-PROVERA
Contraceptive Injection?
You will have a physical examination before your doctor prescribes DEPO-PROVERA. Itis
important to tell your health-care provider if you have any of the following:
- a family history of breast cancer
- an abnormal marnmogram (breast x-ray), fibrocystic breast disease, breast nodules or lumps, or
bleeding from your nipples
* kidney disease
- irregular or scanty menstrual periods
- high blood pressure
" migraine headaches
- asthma
- epilepsy (convulsions or seizures)
+ diabetes or a family history of diabetes
- a history of depression
- if you are taking any prescrnption or over-the-count# medications
This product is intended to prevent pregnancy. It does not protect against
transmission of HIV (AIDS) and other sexually transmitted diseases such as
chlamydia, genital herpes, genital warts, gonorrhea, hepatitis B, and syphilis.
What if I want to become pregnant after using DEPO-PROVERA Contraceptive
Injection?
Because DEPO-PROVERA is a long-acting birth control method, it takes some time after your last
injection for its effect to wear off. Based on the results from a large study done in the United States,
for women who stop using DEPO-PROVERA in order to become pregnant, it is expected that
about half of those who become pregnant will do so in about 10 months after their last injection;
about two thirds of those who become pregnant will do so in about 12 months; about 83% of
those who become pregnant will do so in about I5 months;and about 93% of those who become
regnant will do so in about 18 months after their last injection. The length of time you use
DEPO-PROVERA has no effect on how long it takes you to become pregnant after you stop using it
What are the risks of using DEPO-PROVERA Contraceptive Injection?
I.Irregular Menstrual Bleeding
The side effect reported most frequently by women who use DEPO-PROVERA for
contraception is a change in their normal menstrual cycle. During the first year of using
DEPO-PROVERA. you might have one or more of the following changes: irregular or
unpredictable bleeding or spotting, an increase or decrease in menstrual bleeding, or no bleeding
at all. Unusually heavy or continuous bleeding, howeve; is not a usual effect of DEPO-PROVERA;
and if this happens, you should see your health-care provider right away. With continued use of
DEPO-PROVERA, bleeding usually decreases, and many women stop having periods completely.
In clinical- studies of DEPO-PROVERA, 55% of the women studied reported no menstrual
bleeding (amenorrhea) after I year of use, and 68% of the women studied reported no menstrual
bleeding after 2 years of use. The reason that your periods stop is because DEPO-PROVERA
causes a resting state in your ovaries. When your ovaries do not release an egg monthly, the
regular monthly growth of the lining of your uterus does not occur and, therefore, the bleeding
that comes with your normal menstruation does not take place. When you stop using
DEPO-PROVERA your menstrual period will usually, in time, return to its normal cycle.
2.Bone Mineral Changes
Use of DEPO PROVERA may be associated with a decrease in the amount of mineral stored in
your bones. This could increase your risk of developing bone fractures. The rate of bone mineral
loss is greatest in the early years of DEPO-PROVERA use, but after that, it begins to resemble the
normal rate of age-related bone mineral loss. -
3.Cincer
Studies of women who have used different forms of contraception found that women who used
DEPO PROVERA for contraception had no increased overall risk of developing cancer of the
breast, ovary, uterus, cervix, or liver However; women under 35 years of age whose first exposure
to DEPO-PROVERA was within the previous 4 to 5 years may have a slightly increased risk of
developing breast cancer similar to that seen with oral contraceptives. You should discuss this with
your health-care provider
4.Unexpected Pregnancy
Because DEPO-PROVERA is such an effective contraceptive method, the risk of accidental
prenancy for women who get their shots regularly (every 3 months [I 3 weeks]) is very low.
While there have been reports of an increased risk of low birth weight and neonatal infant death
or other health problems in infants conceived close to the time of injection, such pregnancies are
uncommon. If you think you may have become pregnant while using DEPO-PROVERA for
contraception, see your health-care provider as soon as possible.
S.A~lergic Reoctions
Some women using DEPO-PROVERA Contraceptive Injection have reported severe and
potentially life-threatening allergic reactions known as anaphylaxis and anaphylactoid reactions.
Symptoms include the sudden onset of hives or swelling and itching of the skin, breathing
difficulties, and a drop in blood pressure.
6.Other Risks
Women who use hormone-based contraceptives may have an increased risk of blood clots or
stroke. Also, ifa contraceptive method fails, there is a possibility that the fertilized egg will begin
to develop outside of the uterus (ectopic pregnancy). While these events are rare, you should
tell your health-care provider if you have any of the problems listed in the next section.
What symptoms may signal problems while using DEPO-PROVERA
Contraceptive Injection?
Call your health-care provider immediately if any of these problems occur following an injection
of DEPO-PROVERA:
+ sharp chest pain, coughing up of blood, or sudden shortness of breath (indicating a possible clot
in the lung)
" sudden severe headache or vomiting, dizziness or fainting, problems with your eyesight or
speech, weakness, or numbness in an arm or leg (indicating a possible stroke)
- severe pain or swelling in the calf (indicating a possible clot in the leg)
- unusually heavy vaginal bleeding
- severe pain or tenderness in the lower abdominal area
persistent pain, pus, or bleeding at the injection site
What are the possible side effects of DEPO-PROVERA Contraceptive Injection?
(.Weight Goin
You may experience a weight gain while you are using DEPO-PROVEPA. About two thirds of
the women who used DEPO-PROVERA in clinical trials reported a weight gain of about 5 pounds
during the first year of use. You may continue to gain weight after the first year Women in one
large study who used DEPO-PROVERA for 2 years gained an average total of 8.1 pounds over
those 2 years, or approximately 4 pounds per year. Women who continued for 4 years gained an
average total of 13.8 pounds over those 4 years, or approximately 3.5 pounds per year Women
who continued for 6 years gained an average total of 16.5 pounds over those 6 years, or
approximately 2.75 pounds per year.
2.0ther Side Efects
In a clinical study of over 3,900 women who used DEPO-PROVERA for up to 7 years, some
women reported the following effects that may or may not have been related to their use of
DEPO-PROVERA: Irregular menstrual bleeding, amenorrhea, headache, nervousness, abdominal
cramps, dizziness, weakness or fatigue, decreased sexual desire, leg cramps, nausea, vaginal
discharge or irritation, breast swelling and tenderness, bloating, swelling of the hands or feet,
backache, depression, insomnia, acne, pelvic pain, no hair growth or excessive hair loss, rash, hot
flashes, and joint pain. Other problems were reported by very few of the women in the clinical
trials, but some of these could be serious. These include convulsions, jaundice, urinary tract
infections, allergic reactions, fainting, paralysis, osteoporosis, lack of return to fertility, deep vein
thrombosis, pulmonary embolus, breast cancer, or cervical cancer If these or any other problems
occur during your use of DEPO-PROVERA, discuss them with your health-care provider.
Should any precautions be followed during use of DEPO-PROVERA
Contraceptive Injection?
(.Missed Periods
During the time you are using DEPO-PROVERA for contraception, you may skip a period, or your
periods may stop completely. If you have been receiving your DEPO-PROVERA inections
regularly every 3 months (13 weeks), then you are probably not pregnant. However if you think
that you may be pregnant, see your health-care provider:
2.Loboratory Test Interocsons
If you are scheduled for any laboratory tests, tell your health-care provider that you are using
DEPO-PROVERA for contraception. Certain blood tests are affected by hormones such as
DEPOPROVERA
JDrug Interactions
Cytadren (aminoglutethimide) is an anticancer drug that may significantly decrease the
e activeness of DEPO-PROVERA if the two drugs are given during the same time.
4.Nursing Mothers
Although DEPO-PROVERA can be passed to the nursing infant in the breast milk, no harmful
effects have been found in these children. DEPO-PROVERA does not prevent the breasts from
producing milk, so it can be used by nursing mothers. However; to minimize the amount of
DEPO-PROVERA that is passed to the infant in the first weeks after birth, you should wait until
6 weeks after childbirth before you start using DEPO-PROVERA for contraception.
How often do I get my shot of DEPO-PROVERA Contraceptive Injection?
The recommended dose of DEPO-PROVERA is 150 mg every 3 months (13 weeks) given in a
single intramuscular injection in the buttock or upper arm. To make sure that you are not pregnant
at the time of the first injection, it is essential that the injection be given ONLY during the first
5 days of a normal menstrual period. If used following the delivery of a child, the first intection of
DEPO-PROVERA MUST be given within 5 days after childbirth if you are not breast-feeding or
6 weeks after childbirth if you are exclusively breast-feeding. If you wait longer than 3 months
(13 weeks) between injections, or longer than 6 weeks after delivery, your health-care provider
should determine that you are not pregnant before giving you your injection of DEPO-PROVERA
6
Rx bnly
CB-7-S
Pharmacia
&Upjohn
Pharmacia & Upjohn Com pany
Kalamazoo, MI 49001, USA
_
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