The Michigan Daily - Friday, March 8, 2002 - 7
Cloning used to repair animal's inhented disease
BOSTON (AP) - For the first time, sci-
entists say they have used the ethically sen-
sitive technology of therapeutic cloning to
repair an inherited disease in a lab animal.
While still far from human use, experts
say this demonstrates the potential power of
the approach to correct many common ill-
nesses that affect people.
Most of the steps in the work have
already been accomplished individually in
lab animals. Scientists have used so-called
therapeutic cloning to make embryonic stem
cells that can develop into many different
kinds of tissue, such as muscle or nerves.
But until now, they have not been put back
into an animal to treat a disease.
The experiments involved repairing an
immune system defect in mice. First, they
made clones of the animals to harvest
embryonic stem cells.
Next, they fixed the genetic defect in
these stem cells. Finally they put the
repaired stem cells into the adult animals,
where they partially overturned the immune
"This really is a tremendous confluence
of very, very challenging technology, wrap-
ping them all together into a model thera-
py," said researcher George Daley. "We are
the first to do this all the way."
The experiments were conducted by
Daley and Rudolf Jaenisch at the Whitehead
Institute for Biomedical Research in Cam-
bridge, Mass. Two reports on the work were
to be posted online today by the journal,
"Putting it all together in sequence is dra-
matic," said Neil Theise, a stem cell biolo-
gist at New York University.
"The fact they are doing it in a model of a
human disease is very canny, and certainly
this will have a big impact on the public
Therapeutic cloning starts with cells
derived from test-tube embryos that are
genetic twins of the recipient.
Many, including President Bush and some
members of Congress, are opposed to
"The fact they are doing it in a model of a human
disease is very canny, and certainly this will have
a big impact on the public debate."
- Neil Theise
Stem cell biologist, New York University
cloning of all forms, including the therapeu-
Some scientists, including Daley, have
proposed calling the procedure "nuclear
transplantation therapy" to avoid confusion
with reproductive cloning, which is intend-
ed to produce a whole person.
The latest experiments were conducted on
inbred mice that had severe immune defi-
ciency because of a genetic defect that pre-
vented them from manufacturing antibodies
in response to infections.
Continued from Page 1
South Quad resident and LSA sophomore Jake Brege
said he understands the need to secure the residence
halls, but locking the outside doors is not an effective
"Locking the outside doors is more of an inconvenience
than a help," Brege said.
"The police patrols are a good idea, but they should be
more proactive. They should do more detective work, rather
the MSA Campus Safety Commission sponsored a panel
discussion regarding residence hall safety last night at the
"In light of the increase in residence hall crime, we
wanted to provide a forum for students to voice their
concerns and listen to University security officials,"
Jenny Nathan, MSA campus safety co-chairman, said.
DPS has issued a $1,000 reward for information leading
to the successful arrest of suspects involved in the peeping
tom incidents in the residence halls. If you have any infor-
mation, contact Sgt. Tim Shannon or Sgt Melissa Overton of
DPS at 763-1131 or call the University's anonymous tip-line
than just walking around."
To help students understand the new
Continued from Page 1
for the GEO to not strike, the Universi-
ty would have to offer counter-propos-
als on each of the issues in the union's
"That is not going to happen,"
The terms of the strike package
include a wage increase, a proposal to
make the hourly rates paid to lower
fraction GSIs the same as those paid to
higher fraction GSIs, the addition of
contractual language not permitting
the use of bottom line budgeting in hir-
ing and a revised grievance procedure.
Child care, health care, GSI training,
and discrimination prevention are also
issues covered in the strike package.
Picard said even if the University
did address all of the issues before
Monday, it still might not be enough.
Of GEO members who returned bal-
lots by Wednesday's deadline, 81 per-
cent voted in favor of the job action.
"I would feel very uncomfortable
overturning that vote," she said.
The possible one-day-long strike
will take place across North and Cen-
tral campuses from 9 a.m. to 6 p.m.
Continued from Page 1
unless it's disturbed ... by some major economic policy,"
cautioning against policies that may "over-steer."
Moskow compared the current recession to its predeces-
sor in the early 1970s, noting the economy today is much
stronger in general.
"We haven't had a reduction in output so far and infla-
tion is low," he said, adding he believed that the "current
recession is probably going to be shorter" than the reces-
sion of the 1970s. Moskow also said this recession "is
clearly better than most economists predicted."
As for future rate cut decisions and economic growth,
the speakers remained tight-lipped. But as Moskow
observed, "we can never eliminate recession."
Becky Blank, dean of the School Public Policy and moder-
ator of the panel discussion, said over the past century, reces-
sion is a "topic that is always current" with each decade.
Government economic policies, in dealing with recessions,
should always "do what's right in the long run," Gramlich said.
The Gerald R. Ford Presidential Library and the School of
Public Policy sponsored the panel.
Continued from Page 1
from the legal side of the University, he believes she is the
best person for the job.
"Although it is something of an unusual choice, in my
way of thinking, she was just at the head of the class. On a
scale of one to 10, she was a 12," Dixon said. "Instead of
selecting a tight end or a running back we went to the very
Barry said one of her first missions as managing director
will be to begin building the institute's staff.
"My position for the institute is going to be forms of sup-
port for the scientific staff by taking on the administrative
tasks," Barry said.
The Office of the General Counsel is currently looking
for a replacement for Barry. Until the position is filled, Gen-
eral Counsel Marvin Krislov will take over Barry's role in
the University's legal team.
"I've been very involved all along and as the case
moves forward I will assume more of the day-to-day
management, but I've got a very strong legal team,"
and end with a rally.
"One day could make all the differ-
ence," de Leon said at a stewards'
meeting Tuesday night.
GEO said that puts a lot of pressure
on the walk-out.
"We're planning to be as disruptive
as possible," GEO employee Rodolfo
Palma-Lulion said, adding that pick-
eters will be careful not to break any
Legally, Department of Public Safe-
ty spokeswoman Diane Brown said
picketers cannot physically stop people
from entering buildings, block
entrances or obstruct traffic.
"You can't have two big huge guys
standing in front of a door keeping
people away," she said, adding that
picketers can stand near entrances, on
sidewalks and grass, or be in lobbies
inside University buildings.
Brown said violators of those rules
could be arrested, prosecuted and face
a 90-day jail sentence. International
students who are arrested could face
more severe punishment.
"If we arrest someone for picketing
and they are on an international visa,
we are obligated by law to inform the
(Immigration and Naturalization Ser-
vices);' Brown said.
But Brown said she is not expecting
many problems on Monday.
Though GEO members are encour-
aging students not to attend classes
Monday and some professors have
agreed to cancel classes, University
Spokeswoman Julie Peterson said the
University is doing what it can to
ensure all classes have instructors.
"We know that despite our best
efforts, some classes will not meet, but
we really do expect the majority of
classes to meet as scheduled," she said.
And despite what she called an
unproductive session last night, Peter-
son said the University remains opti-
mistic that a contract agreement is not
"We didn't make very much
progress (last night). Out of three
hours of bargaining, GEO spent two
hours in caucus to talk amongst them-
selves," Peterson said, adding the Uni-
versity's bargaining team was
disappointed at the lack of time spent
in negotiations. "We are convinced
with some good, hard work together,
we could get to a contract agreement
and we are willing to put that effort in
if that's what it takes."
Paying $4 to $6
for top C1)'s in
Open 7 days
The selection is
Continued from Page 1
ing Plastic Inevitable." Off-site additions to the festival will
include late-night performances at the Firefly Club by artists
Craig Baldwin as well as Kapt. Sally and Crew.
On Tuesday at 5 p.m., journalist and provocateur Michael
Moore will also be showing clips from his film on gun con-
trol and signing his book "Stupid White Men and Other
Excuses for the State of the Nation."
Vicki Honeyman, director of the festival for the past 15
years, said that the 40th anniversary is special because it is
a chance to "honor our past and look at our future."
By examining the beginnings of the festival, such as
having founder and former director George Manupelli
screen some of his work, people can see why the continu-
ing commitment to 16 mm film is so important for helping
the festival stay true to its cause, or as Honeyman said
"keeping (its) identity."
Managing Assistant Director Chrisstina Hamilton said that
the festival is a "sounding board for all the voices in our
greater community ... for them to say what they need to say."
Sunday's opening gala, starting at 5:30 p.m., is more
extensive than years past. In addition to the traditional cock-
tail party, Liberty Street is being closed down for the Lux
Mundi street parade, featuring a Chinese lion dance, and
performance artist Pat Oleszko's sculpture garden.
Inside the theater, John Nelson, who won an Academy
Award for Visual Effects for "Gladiator," will be talking
about his work, and Oleszko will perform.
One of the unique aspects of the Ann Arbor Film Festi-
val is the range of material that is assembled for the
screenings. "Some important works are not for everybody,
... There's probably something in each show that you will
love and hate," Hamilton said.
Honeyman, said that although she loves all types of
film, she is partial to the short, experimental films, say-
ing, "It's harder to make a one minute film than it is to
make an hour long one ... most narrative films that are
released are stupid love stories."
Honeyman also said the festival surpasses other such
events because, "We're not afraid of experimental film.
We're more afraid of narratives. We're here to show the
work that doesn't have many other venues."
However, she stresses that the festival does not and
will not have a student category, because, "We're not an
amateur festival. Most student films are not ready to be
shown at this type of festival."
The screenings, which cost $7 each or $50 for the whole
week, run all day, with events from early afternoon to late
night. "Show up anytime - you'll get a great show every
night," said Hamilton.
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