01-1-- LOCAL/STATE The Michigan Daily - Thursday, September 7, 2000 - 3A RESEARCHl Bollinger ready for fourth annual fun run 4 New model for HIV destruction developed A new HIV model developed by University scientist Denise Kirschner helps show how HIV destroys the infected imrthune system. Kirschner's research, which was pub- lished in The Journal of AIDS, shows that the immune system is destroyed by accelerating a normal process called homing, which diverts white blood cells fiom the bloodstream to the lymph stem. The mathematical model was devel- oped in collaboration with G.E Webb of Vanderbilt University, after the accel- erated homing theory was proposed by Miles Cloyd, a professor at the Univer- rsity of Texas Medical Branch at Galve- ston. The new model shows thatCD4 cells, a type of white blood cell, self- struct in the lymph system and that 1IlI death occurs as a rsult of exposure to biochemical sigas involved in the homing process. Kirschner hopes to develop a model for the role of co-receptors involved in HIV binding to CD4 cells. Understanding the relationship between the IJIV virus and the immune system can help in the development of more effective treatments for AIDS. olymersmay top blood clotting University graduate student Huiping Shang presented results of recent stud- ies involving polymers made of nitric- oxide releasing particles for use in biomedical devices at the American Chemical Society meeting in Washing- ton D.C. las month. The polymers contain tiny silica par- les that release low levels of nitric oxide gas and are designed to mimic human endothelial cells. Researchers found that polymers that release nitric oxide could help prevent the formation of blood clots on biomed- ical devices used in heart bypass surgery, kidney dialysis or extracorpo- real membrane oxygenation. These devices include tubing, equip- ment or plastic bags which come in ect contact with blood. Scientists hope to use NO-releasing polymers to coat implantable blood sensors, which are in development at the University, but would continuously monitor vital electrolytes and blood gases in critically ill patients. U' researchers chosen for web 9age design The National Science Founda- tion has chosen researchers at the University's School of Information to be part of a team that designs a Web-based, national network for collaboration in earthquake engi- neering. The team, led by Tom Finholt, will work to link researchers and facilities at aout 25 universities with high-perfor- nce networking, shared databases and computer modeling and simulation tools. The network is intended to ease the scientists" dependence on physical experiments and replace them with the ability to conduct computer simulations and models. The researchers chosen for the team have already played a key role in devel- ng a similar network for the Space ysics and Aeronomy Research Col- laboratory, also funded by the National Science Foundation. Other members of team include researchers from the National Center for Supercomputing Applications and the Mid-America Earthquake Research Center, the University of Illinois depart- ment of civil engineering, the Depart- ment of Energy's Argonne National Laboratory and the University of them California's Information Sci- ences Institute and department of civil engineering. -Compiled 1hDaily Staff Reporter Sindsev Alpert The men's and women's cross country teams are scheduled to run with Bollinger By Lindsey Alpert Daily Staff Reporter University community members don't have to wake up to the sound of an alarm clock to catch the Fourth Annual Fun Run with President Lee Bollinger tomorrow. The starting gun goes off at noon this year, several hours later than past runs. "We'll hopefully gain more success in attract- ing students," said Jim Kosteva, chair of the Fun Run planning committee. "There's probably no ideal time to conduct any event where you can eliminate all conflicts, but we'll try 12 o'clock this year and see how it works." For $1.50, the Central Campus Recreation Building will provide runners in the five-kilome- ter race with a locker, shower and towel. "We simply asked if the CCRB might be able to make themselves available to people who may not have access and they've been gracious to pro- vide lockers," Kosteva said. The Office of the President will provide water, juice and bagels after the event. Partici- pants who register early will also receive a T- shirt. "The event is important because it pro- vides a number of different opportunities," Kosteva said. "The first opportunity is in providing a casual setting to meet the presi- dent of the University and enjoy a little bit of exercise with him. The second opportunity is to appreciate a unique university facility such as the Nichols Arboretum." Registration begins at 11 a.m. tomorrow morning at the Burnham House. Members of the men's and women's cross country team will join Bollinger at the run. "I think it's a good idea to give students a chance to interact with the president and promote fitness," Engineering junior Brock Partee said. "Maybe get a free T-shirt out of the deal." Past attendance has averaged about 150 par- ticipants and is expected to be about the same this year. The time change may help bring out more students, Partee said. "There's a lot of classes then, but it will probably help in general to get more of the student body to come out." The event is open to runners and walkers of all skill levels. Medical staff will be on hand at the event in case of any problems. "This is a low-key casual opportunity," Koste- va said. Although the event scheduled as a low-pres- sure ice breaker, some students have no interest in attending the event. "I have too many other problems the Univer- sity has given me to deal with. Dance marathon Tire recall prompts review of auto industry practices DETROIT (AP) - The furor over 6.5 million recalled Firestone tires linked to 88 deaths has exposed one of the quirks of the U.S. auto industry: Unlike every other part of a vehicle, automakers don't guarantee tires, and hand off customer problems to the tire maker. That lies at tlrn heart of questions about how Ford Motor Co. and Bridgestone/Firestone Inc. investigated reports of problems with Firestone tires. The recall has already convinced Ford CEO Jacques Nasser that standards should change, and may lead other automakers to similar conclusions. "I think this has given the automotive industry cause for concern," Nasser said yesterday. "It's very clear to us now that we need to rethink that process with the tire companies." It's standard practice among automakers to closely watch warranty costs and consumer complaints - not just for signs of a defective part, but to keep buyers happy. The practice of having tire companies handle warranty claims is so old and accepted there's no con- sensus about why it began. But when Ford started investigating reports of tire failure overseas in 1998, and looking for similar prob- lems in the United States, it had little data to a.nalyze. Bridgestone/Firestone and Ford worked together to examine small groups of tires, but the larger problem wasn't found until Ford worked out a deal in July with Bridgestone/Firestone to examine thousands of claims from the tire maker's files. Among major automakers, only General Motors Corp. covers tires under its basic warranties in the United States. Brook Lindbert, GM's director of tire. and wheel systems, said the company changed its sys- tem in 1996 because customers who had problems with their tires were getting shuffled between dealers and tire stores. The newer approach "gives customers the opportuni- ty to approach dealers or tire manufacturers to address a tire concern, and it gives us information as well that would otherwise not be available," he said. Tire makers say they're willing to share data with automakers, but do so only when asked about a specif- ic problem. GM simply passes the claims along, but in the process gets an early warning about any problems. All auto industry suppliers are under more pressure to take a larger role in handling warranty claims, said Neil De Koker, executive director of the Original Equipment Suppliers Association. In the past, automakers simply absorbed the warranty costs of a particular part. Now, more automakers are setting goals for warranty costs; if a part fails to meet the goal, thq supplier has to pay. "You're going to see an increase in the complet reviews of data shared between automakers and supplir- ers," De Koker said. "There will be requirements fo( data exchange, so in the event there is a problem, atk (automaker) can get to the source of the problem morn quickly." JUSTIN FITZPATRICK/Daily LSA seniors Joanne Alnajjar and Erin Perrone dance on the Diag to promote Dance Marathon, a springtime activity that raises money for Children's Miracle Network and William Beaumont Hospital in Royal Oak, Stabenow challenges Abrtaham to debates EAST LANSING (AP) - U.S. Rep. Debbie Stabenow (D-Lansing) yester- day challenged U.S. Sen. Spencer Abra- ham (R-Auburn Hills) to three televised debates, but the proposal is at a stand- still since the candidates can't agree on which debates they'll do. "The people, the voters, have the right to hear directly from us," said Stabenow, a Lansing Democrat hoping to knock off the first-term incumbent. Abraham's campaign staff said the Auburn Hills Republican already has accepted a debate invitation from the Economic Club of Detroit and ques- tioned why Stabenow hadi't agreed to participate. "Senator Abraham is eager to debate Representative Stabenow. Let's agree to the Detroit Economic Club debate today and meet soon to discuss additional debate options," Abraham campaign manager Joe McMonigle wrote in a letter to Stabenow's cam- paign. Stabenow's campaign hasn't declined or accepted any debate invita- tions, spokesman Robert Gibbs said. Instead, in a letter to Abraham released yesterday, Stabenow proposed three live, hour-long debates that would be broadcast statewide during prime time. Stabenow wants the debates to be in a "town hall" format, with an audience of preselected independent voters who would ask the candidates questions. "We're talking maximum exposure to voters, and that real people are ask- ing the questions," Stabenow said. "This is an important step in this cam- paign" Abraham campaign spokesman Joe Davis said Abraham's re-election cam- paign has received numerous offers for debates but considers the Economic Club "an excellent forum." He said U.S. Sen. Carl Levin, (D-Mich.) debat- ed Republican challenger Ronna Rom- ney before the Economic Club in 1996. Abraham's campaign staff said the Economic Club debate was tentatively scheduled for Oct. 16 and that it's open to suggestions from Stabenow's cam- paign. "We'll get together soon and talk about other debate ideas," Davis said. "We're pretty confident in our debating skills. We don't have any misgivings or indecision." Vivian Castanier, an assistant to Economic Club President William Hailing, said she was unaware that a date had been set and said she thought Hailing was still negotiat- ing with Abraham and Stabenow about a possible debate. Hailing was unavailable yesterday for com- ment. Gibbs said Stabenow would appear at the Economic Club if Abraham would participate in the three town hall debates. "Our proposal is to stop hiding behind TV ads and let real voters ask real questions," Gibbs said. In a poll released late last month, Abraham held a 43 percent to 34 percent lead over Stabenow. The poll, conducted by Mitchell Research and Communications Inc. of Lansing, questioned 600 likely Michigan voters and had a margin of error of plus or minus 4 percent- age points. Abraham's campaign suggested Stabenow's call for debates was moti- vated by her poll numbers. "They're struggling for press cover- age and they did-a press conference today to help them pick up their cam- paign," Davis said. But Stabenow says debates are an important part of the campaign. "The importance of the debates is to have both of us be there and to have to look people in the eye," she said. "I think it's important that people get accurate information, and I know that accurate informa- tion is in my favor." EVER WANTED TO INTERVIEW A BAND, BASKETBALL PLAYER OR PRESIDENTIAL HOPEFUL? FIND OUT ABOUT WRITING FOR THE DAILY. MASS MEETINGS: SEPT. 12, 14, AND 18 ALL AT 7 P.M., 420 MAYNARD ST. ,. >, k f THE CALENDAR What's happening in Ann Arbor today EVENTS bdyme@umich.edu cuss spirituality and its mean- T"Rhythm Student Tap Dance Coin- ing, Guild House, 7:30 p.m. - 9 Madrichim Orientation, Soonsored pany," Mass meeting, Union Tap- p.m., 6625189 ---r,....,, oOn- -®Itrndnctr~inn to the Mahavana