The Michigan Daily - Friday, October 20, 2000 - 3
'Man seen hitting
others with cane
Four men were seen fighting out-
side the School of Social Work Mon-
day afternoon, Department of Public
-Safety reports state.
One man was seen knocking over
two others with a cane. Officers made
contact with the men and a report on
the incident was later filed.
sets off fire alarm
A fire alarm in the Law Quad locat-
ed sounded early Tuesday morning,
DPS reports state.
Reports state the cause of the alarm
'was a bag of burned popcorn
Driver refuses to
pay parking fee,
iyells at attendant
A parking booth attendant in the
Fletcher Street parking structure report-
ed that a man in a Dodge Ram pick-up
truck yelled at her Tuesday afternoon
and refused to pay for his parking.
It was also reported that after the
man refused to have his parking ticket'
'validated the attendant allowed the
.1man to exit without payment,
A female resident of the Mosher
Jordan Residence Hall allegedly
dlapped her roommate across the face
ate Tuesday night, DPS reports state.
The females were separated but
when officers arrived on the scene the
suspect had already left.
OIand dryer melts,
catches on fire
Smoke was reported coming from aa
second floor women's bathroom of the
Michigan League on Monday morn-
ing, DPS reports state.
The smoke resulted from a hand
dryer catching fire and melting. Limit-
"ed damage was reported.
Jires slashed in
LSA parking lot
The tires of a vehicle parked in the
LSA Building visitor's lot located at
East Jefferson and Maynard streets
were reported slashed Monday afte--
noon, DPS reports state.
Thetires have been repaired but
UIPS did not report having any sus-
tin the incident.
at 'U' Hospitals
A patient at the University lospi-
tals was struck Monday evening, DPS
Although the subject left the hospi-
t'al, he later returned and officers
,poke with all parties involved before
filing an incident report.
. Estudents given
t 7T~wo students were issued citations
for being in possession of alcohol
early Tuesday morning in the l3ursley
Residence Hall located on North
Campus, DPS reports state.
One of the students was found
vomiting in a bathroom. Both subjects
# re cited and later released.
man enters office
A homeless man wandered into an
office in the Michigan Union on
Wednesday afternoon and sat down,
DPS reports state.
After staff members concerned
about the man's well-being notified
DPS, the man, who was found to be
*toxicated, passed out. lie was trans-
ported to the University Hospitals'
emergency room via ambulance.
Comnpilel h- Dailr Sita/ffIRe porIter
researchers find gene for breast cancer
By Lindsey Alpert
I3iiv Staff Reporter
In the midst of Breast Cancer Awareness Month,
a recently published study in the journal Cancer
Research sheds some light on the genetics of
inflammatory breast cancer.
IBC, regarded as the most deadly form of locally
advanced breast cancer, accounts for 6 percent of
all breast cancer diagnoses in the U.S. each year.
IBC spreads so quickly it often reaches lymph
nodes or other parts of the body by the time it's
diagnosed, leaving only 45 percent of women with
the disease alive and disease free after five years.
Researchers at the University have discovered
the gene responsible for IBC, which helps to
explain the disease and may aid in its treatment.
"It's really encouraging," said Kenneth van
Golen, co-author and research investigator in the
department of internal medicine. "Clinically this
disease has been in literature for 120 years, but up
until 1999, nobody knew anything about the genet-
ics of it."
Author and internal medicine associate Prof.
Sofia Merajver said the team discovered that the
gene, RhoC GTPase, was particularly active in a
sample of breast cancer.
"By takig the gene and manipulating it, there is
proof of principle that this gene is actually causing
the tumor," she said.
RhoC genes are present in all cells and are nec-
essary for cell life, but can cause cancer when the*
production is overactive. In normal gene expres-
sion, it helps to arrange the cyioskeleton of the cell
and allow for the cell to move and change shape.
"When (RhoC genes are) overly active it makes
the cell very invasive with high mobility and it
doesn't seem to respect the environment" Merajver
The higih mobility allows the cancer to move
throughout the body very quickly and spread to
lymph nodes, blood and anywhere else in the body.
"Patients have tumor cells that are literally
crawling through the body," van Golen said.
The researchers inserted the RhoC gene into
normal breast cells and compared the results with
cells from an IBC tumor tissue sample.
"We identified genes that were important in
inflammatory breast cancer," van Golen said.
"We've taken one of the genes and put it into a nor-
mal breast cell and we've basically re-made the
cancer phenotype. We've made the normal cell
look like cancer."
The tests were performed in test tubes and then
in laboratory mice. About 25 percent of the mice
that were given the RhoC cells formed tumors
while none of the mice that received normal breast
cells had tumors.
"We found that the cancer we created in test
tubes caused cancer in the animals." Merajver said.
"Sometimes you can cause things in the laboratory
that aren't realistic in animals"
But, the scientists believe that there are other kev
genetic factors involved in forming the tumors. In a
previous study the team found that the under
expression of'a tumor suppressor gene called LIBC
(Lost in Inflammatory Breast Cancer), may also be
a cause. The team will continue the research to find
a molecule either upstream 6r downstream from
the RhoC gene, or even the gene itself that will
deactivate the gene.
While there are no treatments based on the dis-
covery of the gene available clinically, they are
being developed in the laboratory.
"We want to get more specific function and
eventually cure breast cancer;" said health science
research associate Zhi-Fen Wu. "We got lots of
good data. This paper is just a beginning."
The study was published in the Oct. 15 issue of
By Jen Fish
FLINT -Although i
agenda, there were som
yesterday's meeting of tI
Board of Regents at the
Flint campus, with more
the English course "Hox
Male Homosexuality and I
The course, taught by
David Halperin, has becor
this years regents election
Hornig (R-Grand Haven
out against the class, but4
have said they have no plar
While criticism of the
gored since its initial listi
course guide, there was a
class at yesterday's meetint
Gary Glenn, president c
can Family Associationr
delivered'a petition to ther
by about 15.000 Michiga
"Gov. Engler, the Legisla
U-M Board of Regents to
possible to stop U-M o
using my tax dollars to rc
students into a class whos
tion is to experiment' in t
of students into a high-ris
homosexual that is immor
a serious threat to personal and public
I -alpetin, who was not at the meeting,
t was a short repeatedly has said the literature class is
e surprises at not an effort to "recruit" students into a
he University homosexual lifestyle.
University's Glenn also accused the regents of
criticism for committing a "politically correct doubly
v to Be Gay: standard" by divesting its tobacco stock;
nitiation." but endorsing a class that Glenn says is
English Prof. more dangerous than smoking.
me an issue in "The reckless, negligent and hypor
. Regent Dan critical double standard by which the
n) has spoken University glorifies politically correct
administrators but deadly homosexual behavior wi
ns to cancel it. cost lives, including, over time, no.
class has lin- doubt, some of the same U of M stu-
ng in the fall dents you made much of protecting
new twist to from the politically incorrect behavior
iation of the of smoking,; Glenn said.
0. 'If the lives of U of M students are
of the Ameri- worth protecting from the hazards of'
of Michigan, smoking, they are worth protecting fron
regents signed the hazards of even deadlier homosexu=
nders urging al behavior" he added.
iture, and the Glenn pointed to a study by Oxford.
do everything Un iversity that claimed the li fe
fficials froi expectancy of gay and bisexual men is
ecruit teenage eight to 20 years less than for all men.
e stated inten- In accordance with the regents' pub=
he 'initiation' lie comments policies, the board mem-
k lifestyle of hers and University executive officers;
al, illegal and did not respond to Glenn's statements. E
U'A'IL)D KAZ LDaly
LSA sophomore Louisa Kennedy stretches out to catch a flying disc yesterday in the Diag.
issues discussed in
honor of Lane Hall
c E liYCE 'cgttn ttil
JOIN THE TEAM.
By Susan Luth
I Xilt'Siull Rcptoricr
As part of this month's celebration
of the newly refurbished Lane Hall,
a building devoted entirely to
women's studies, a group of Michi-
gan faculty met yesterday to take
part in a panel discussion about the
working conditions and opportuni-
ties for women in today's work place.
"As a graduate student close to
finishing, I'm thinking of jobs out
in the real world," physics graduate
student Mia Franke said. "I wanted
to hear some perspectives of what
it's like in the work force for
leach faculty member spoke of a
different field of work, including
medicine, science, art and law. The
focus of the discussion centered
around women and how they strug-
gle in the work force compared to
men. For each field, the panelists
presented statistics to show that
women are treated unequally in their
jobs and how generally, across all
fields of work, women are discrimi-
"Something is so wrong here,"
geological sciences Prof. Lynn Wal-
ters said. "The statistics are shock-
ing. They're just heartbreaking.
.There are remedies, but first you
have to recognize the problem."
"We need to stop self-censoring
ourselves and remeiber who we're
protecting when e don't speak up;'
associate Art aid" esin and
women's studies Prof. Carol Jacob-
They emphasized that statistics
showed women work in the lower
ranks of their fields for less money
Discussion also surrounded the
thought that women are taught from
a very early age that it is polite to
let men step ahead in the work force
and that the practice of teaching
girls this in their childhood needs to
The panel's discussion is oneof
many events that are taking place
throughout the month in celebration
of the newly renovated Lane I hall
which is located at the intersection
of State and Washington streets. The
Lane hall opening ce-lebration takes
place today, 25 years after the found-
ing of women's studies on campus.
The event begins at 9 a.m. in
Lane Hall with a rowindtable discus-
sion lead by doctoral students in
women's studies. This will be fol-
lowed by a panel discussion, a rib-
bon-cutting ceremony and an open
house. Throughout tie afternoon a
fair on State Street will feature jug-
glers, music and other forms of
entertainment. At 4 p.m., Universi-
ty President Lee Bollinger and
Provost Nancy Canto-r will give pre-
sentations and award-s as part of the
The University of Michigan
REC Department of Recreational Sports
SPORTS H APPENING
INTRAMURALS INTRAMURAL SPORTS PROGRAM
WALLYBALL FLAG. FOOTBALL
ENTRIES TAKEN: EN RIES TAKEN:
Monday 10/23 ONLY Monday 10/23 ONLY
11:00 AM to 5:30PM 11:00 AM to 5:30 PM, IMSB
ENTRY FEE: ENTRY FEE:
$50 per team $75 per team
MANAGER"S MEETING: MANAGER'S MEETING:
Weds 10/25, 7:15 PM, IMSB Weds 10/25, 6 & 9 PM, IMSfl
PLAY BEGINS: PLAY BEGINS:
Thurs 10/26 Thurs 10/26
IMSB Mitchell Fields
ENTRIES TAKEN: Thurs 11/30, 4:30 PM, IMSB
Mon 11/27 to Weds 11/29 ENTRY FEE:
11:00 AM to 4:30 PM, IMSB
i $35 per team
ENTRY FEE: $5 per individual
S$35 per team MANAGER'S MEETING
MANAGER'S MEETING: Thuns 11/30, 6:30 PM, IMSB
Thurs 11/30, 6:00 PM, IMSB
TOURNAMENT DATES: Tues - Thurs 12/5 - 12/7
Sat & Sun 12/2 & 3, IMSB Sport Coliseum
What's happening in Ann Arbor this weekend
FRIDAY entrance, take one of the eleva- Film and Video Studies, 5:00
tors on the left), 936-3626 p.m., Michigan Theater
0 "Indian History in Geographical and U "The Real Story Behind Falun
Sponsored by the Center for Gong," Sponsored by Amnesty
South and Southeast Asian Stud-SATURDAY International, 7:00 p.m., Michi-
ies, Brown Bag Lecture Series. gan Union Pond Room
11:45-12:15 p.m., 1636 SSWB, "The Rhythm of Africa Save the