Thursday, October 28, 1976 TEMCIA AL THE MICHIGAN DAILY Page Three Scientists report DNA breakthrough SAN FRANCISCO (A') - Sci- As a result of recombinant In entists experimenting with DNA research, he said, cellsn genes have "ordered" a tiny could be ordered to produce cell to produce an enzyme, a drugs like insulin, essential to discovery they say may lead to the survival of about a third of1 new, less expensive sources of the nation's 10 million diabetics. If insulin and other drugs. Boyer, who directed the re-! In an interview before pub- search at the University of Cali-b lication today of the findings in fornia - San Francisco, said suchI the journal Nature, Dr. Her- production might be only fivea bert Boyer said scientists may years away.I soon be able to reconstruct The genetic engineering is' genes that will turn cells into based on the research reported "factories" for the production in 1973 and 1974 and for which of biological substances. the University of California and "WE'VE GONE out of theStaUforsierCity rae ndo area of basic science," Boyer. Stanford University have to- said, "into the area of practical gether applied for a patent oni application." the commercial use of the tech- DAILY OFFICIAL BU!LLETIN1 Thursday, October 28, 1976 cember 1. Applications available. - Day Calendar W. R. Grace & Co., New York. WUOM: "Michigan Ballot Issues: wall interview Thursday, Nov. 4: 9 Pro & Con," (program that looks at 'to 5. Liberal Arts majors' in theirt Proposals A,B,C,&D); 10 am. junior year, chemistry background. Human Growth, Development Register in Room 3258 SAB. Films: "Piaget's Developmental The- The Annual Advertising Career ory Conservation." & "Child's Conference sponsored by the Ad- Play," 1025 Angell, 11 am. vertising women of New York Pendleton Ctr: "Open Hearth Foundation is scheduled for Sat.. Series," The Young Vic Co., PAIC, Nov. 6 at Fordham Univ.. Lincoln 2nd fl, Union, noon, Center Campus in Manhattan. Reg-, MHRI: Baron Shopsin (NY Univ) istration Fee $5.00. Participants, sen- "Serotonon & Depression," 1057 tors and graduate students with ma- MHRI, 3:45 pm. jor interest in communications, or Geol / Mineral: Anthony J. Nal- related fields - TV, Broadcasting/ Irett (Univ of Toronto) "Metallo- radio. Further information/registra- genesis & Exploration for NI-Sul- tion material available. tide Deposits," 4001 C C Little, 4 Information available on the Mr.r pm. and Mrs. Spencer T. Olin Fellow-' Ctr Russian, E European Studies:, Ships for Women. Open to students EdwardLipinski (Dean of Polishi the Biogical andtBiomedical Economists, Polish Academy of sciences. Humanities, Physical Sci- Sciences) "Critical Issues of Con- ences and Mat, Bus. Admin., Engr. temporary Socialism: The Polish and others. Details /applications Case," Lee Rm 2, MLB, 3 pm. an te. Microbil": Stephen Cooper ".Ge- available. neticrAnalysis oftNosenser Muta- The Royal Norwegian Council for neti Analyis of NonsenseMutansScientific and Industrial Research in E. col," S Lee Hall, Med Sci cetfcadInutilRsac II, 4 pm. hereby invites young, foreign sc- Int'l Night: French menu; League entists to apply for Postdoctorate cafeteria, 5 pm. Fellowships to undertake research Univ Club: "Sports'nSmorgas- work in Norway. bord," joining Bo Schembechler at Canadian-American and Regional Pep rally after dinner; Union, 6 Studies Program available to gradu- Pm. ate students in the fields of Politi- PIRGIM: 4th fl, Union, 7:30 pm. cal Sl.. Foreign Lang., Antbro., Guild House: Poetry reading, Deb- Sociology, and many other fields. orah Allen, Mary Koral; 802 Mon-__ roe St., 7:30 pm. THE MICHIGAN DAIiv Nat Res: "Debate on Proposal Volume LXXXVII, No. 43 A," Tappan Intermediate chool, Thursday, October 28, 197 7:;30 pm. TusaOtbr2,1~ Music School: Symphony Orch, is edited and managed by students Hill Aud, 8 pm. at the University of Michigan. News PTP: Showcase Series, Barrie's phone 764-0562. Second class postage "What Every Woman Knows," True- paid at Ann Arbor, Michigan 48109 blood Theatre. Frieze, 8 pm. 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B O Y E R ' S W O R K in reconstructing parts of parts for DNA, the basic chemical unit of heredity, "parallel" the break - through announced last August by Har Gobind K'horana and others at the Massachusetts Institute of Technology, the University of California said. The Khorana group succeed- ed in linking complex chains of DNA to duplicate the actual ! gene of a simple bacterium, E. coli, which lives in the human intestine. When this manmade gene was then inserted into the cell, it fnctioned like its real- life model. Boyer explained his group has synthesized a section of - - - - - + .__ DNA that orders the genes of E. coli to produce an enzyme used for digesting milk. Nor- mally the enzyme is produced only when the cell needs it. "NO R M A L L Y THERE'S Scientists think repressor molecules are part of the rea- son one gene in a human fetus will direct cells to form into a hand and another, perfectly identical gene, will order the development of a nose. a protein molecule that sits on top of this genetic segment and B 0 Y E R said the biggest keeps it from working," Boyer stumbling block in making ge- explained. Such molecules, call- netics work for man in produc- those used in the UCSF and MIT research. "Putting it into the cell is a snap," he said. "We have the technology for that. DNA syn- thesis is still very expensive and time consuming." The first known patent for rayon was taken out in 1855 by George Andemars, but rayon was perfected by Sir Joseph Swan in 1883. HALLOWEEN MAKE-UP Featuring full lines of Theatrical Make-up by Stein-Mehron. We carry all you'll need: clown white, grease point, glitter, rouges, colored hsir spray, and much more. Lucky Drugs, Inc. 665-8693 S213 S. MAIN that's on Main between Liberty and Washington OPEN TILL 6 P.M. MON.-SAT. ed "repressors," are important clues to understanding what turns a gene on and off. When the manmade DNA was inserted into the cell, Boyer said, it grabbed the repressor{ molecule away from the cell's own DNA, which then began to order the gene to produce the enzyme. ing insulin and other drugs is the laborious synthesizing of DNA segment sand genes that are more complicated than U I Paid Political Advertisement GEORGE STE DEMOCRAT fir PROSECUTING ATTORNEY ANN ALICIU [ELM CO-0CI TONIGHT: Martin Scorsese's MEAN STREETS (1974) Robert DeNiro and Harvey Keitel burn up the screen in Scorsese's sensual evocation of the underside of New York's Little Italy. Explosively original and daring; at times frightening and funny, MEAN STREETS is above all honest. "Exquisite, savage, com- passionate and brilliant."-Joseph Gelmis. Scorsese Short: THE BIG SHAVE "The hero of MEAN STREETS is a Catholic who believes in hell. He ought to. He's in it."-Joseph Gelmis. $1.25, AUD. A ANGELL HALL TICKETS GO ON SALE OCT. 28 1 I As attorney for the people, and their chief law enforce- ment official, the prosecuting attorney has a more direct and significant impact on the daily lives of county resi- dents, on campus and off, than any other official to be elected November 2nd.4 The prosecuting attorney can concentrate limited criminal iustice resources in such critical areas as rape, rubbery, consumer fraud and environmental abuse: or, like the incumbent, he can waste these resources pursuing victim- less offenses. The prosecuting attorney can see that tenants are protected from unsafe housina, that nursing home patients are protected from physical and fiscal abuse, and that the whole community is protected from collusive price- fixing that artificially inflates prices for groceries and other merchandise; or, like the incumbent, he can ignore these problems. The prosecutina attorney can bring the concept of equal justice closer to reality; or, like the in- cumbent, he can continue with a system of double stand- ards, one for the privileged few and another for the rest of us. An energetic, committed prosecuting attorney can have a positive impact on our lives. George Steeh, a native of Washtenaw County, earned his bachelor's and law degrees from the University of Michigan. He had experience in the best prosecutor's office in the state, where he was a Senior Assistant Prosecuting Attor- ney. He has been chief of a nationally acclaimed Economic Crime Unit. Steeh has extensive experience with both civil and criminal trials and appeals. He has proven ability in effectively managing a staff and case load more than twice as large as the Washtenaw County prosecutor's Steeh is a nationally recognized leader in developing irno- votive,- effective approaches to confront the crime problem. In the prosecuting attorney's office, we need dynamic leadership, effective management and fair treatment of all citizens. George Steeh has the energy, concern and ability to do the job for us. Paid for by Steeh for Prosecuting Attorney I 7/ As Ann Arborsf CAKE SPECIALIST, 4 We'll get the Cake delivered as you want it, fresh, intact, and on time. Whether it is to DETROIT, NEW YORK, or SAN FRANCISCO ... j ~ask us about~ G) 2 TELE-CAKES, SUGAR BIN BAKERY,). "{q' 300 S. Main 761-7532 at the corner of Liberty &!Main 1 IL LEADING BASS OF THE METROPOLITAN OPERA Basso Diaz' rise to international fame has been spectacular since the opening of the new Metropolitan Opera at Lincoln Center when he portrayed the male lead in Samuel Barber's "Antony and Cleopatra." His successes on the world's major operatic stages are combined with guest artist appearances with the great orchestras of the United States and Canada, Europe and South America, and he returns regularly to his home- land, Puerto Rico, to sing at the Casals Festivals. NIVERSITY I!, I bn... lr...o l::Jf;.,s+ E fit_ . f .QED" " ,J( / i I