i

'U' panel monitors DNA studies
(Continued from Page 1)

I

the need for stiffer language in the
Regents' charge to the committee.
Shrodt suggested some of the wording
be changed to clarify the difference
between recommendations for DNA
experiments and requirements.
While Committee C only gave the go-
ahead for five recombinant DNA ex-
periments this year, a great deal of
time was spent developing procedures
for safeguarding lab facilities and in-
suring that medical personnel are
adequately trained and medically

monitored.
Discussion at yesterday's review
meeting brought up the question of
whether the committee can continue to
handle the expected increase in the
number of proposal applications now
that new recombinant DNA labs are
near completion.
THE LABS, equipped with special
features, meet safety guidelines
established by NIH and make recom-
binant DNA experiments more ac-
cessible to University researchers.
The two renovated facilities are "P3"
level labs, or labs certified by NIH to
handle "moderate risk" recombinant
DNA experiments. Committee C hasn't
approved any P3 level experiments this
year, though one is presently under
consideration.
TWO OF THE projects Committee C
approved this year were "P1" level ex-
periments that require no special
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safety precautions other than those
generally followed in all microbiology
research. The remaining three ap-
proved projects are being conducted at
the "P2" level of containment and are
low-risk experiment conducted in
facilities similar to hospital
microbiology labs.
There are also NIH guidelines for
"P4" level facilities, which are roughly
similar to those precautions taken with
moon rocks and chemicals for possible
use in germ warfare. The University
Regents have said they will not
authorize any "P4" level experiments.
At yesterday's meeting, Associate
Vice-President for Research Alvin
Zander expressed surprise at the small
number of recombinant DNA research
proposals filed with Committee C.
"WORD HAS to get around," said
Payne who theorized that the faculty is
wary of the bureaucratic complications
of doing "P3" level experiments.
Asked by,,Medical School Dean John
Gronvall whether the committee can
handle the monitoring of all new ex-
periments, Payne replied, "I hope so,
but the biological monitoring thing
could get out of hand."
Biological monitoring of experiments
require committee members who are
experienced with microbiological
techniques to certify that, the host
cultures for recombinant DNA tran-
splants won't survive outside
laboratory conditions or in the human
body.
The actual biological monitoring
must be done in the P3 lab. Vice-

President for Research Charles
Overgerger said the University might
want to consider a full-time expert on
biological monitoring if Committee C's
burden grows too large.
, Ecology Center representative, Paul
Shrodt suggested the committee con-
sider sponsoring some "medium or
forum to appraise the community of the
development of facilities and reseac"
concerning recombinant DNA research.
DNAlab
nearly
read
(Continued from Paged1)
experimenter and experiment from
mutual contamination.
The hoods were originally tested by
a company hired by the hoods'
manufacturers. While Committee C
"had no reasons to doubt the (test-
ing) process," Payne said committee
members preferred - calling in an
independent firm to test; the hoods
again.
COMMITTEE C members are
presently reviewing a "P3" level pro-
posal by two Medical School profes-
sors, Roy Schmickel and Golder
Wilson. If approved, their experi-
ment to isolate a human DNA gene
will be the first P3 level experiment
at the University.
A third laboratory, located in the
Buhl Research Center for Humah
Genetics, is being remodelled to
accommodate P3 experimentation.
But there are no immediate plans for
Committee C to authorize recombin-
ant DNA research there.

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65/35

VAaril
gives only
one view
-author
(Continued from Page 1)
Hunt told The Daily that his
article, which is. being hailed by the
hospital administration as "the only
publication" that "tells the whole
story," is only intended to present the
VA case from the perspective of the
jurors. "I think that the hospital
thinks that the juror's view is the
proper one," Hunt said.
A jury of nine women and three
men found Filipina Nareiso and
Leonora Perez guilty of poisoning
five patients at the Fuller Road
hospital during the summer of 1975.
The Observer article attempts to
present an in-depth analysis of the
case after talking to several jurors
about their deliberations.
WHILE ADMITTING his article is
not the "balanced" viewpoint it is
being mistaken for, Hunt insists,
however, that he was not "spoon-
fed" information by the prosecution.
"We talked to the prosecution,"
Hunt said, "But the article is based
on the juror's viewpoint."
Hunt said, "Our article is not
meant to convey the truth of the case,
but rather how the jurors saw it."
THE Ann Arbor News reported
yesterday that the VA had purchased
1,000 copies of Hunt's article and
mailed them out at government
expense. Hunt confirmed that copies
were sold to the VA at a cost of 10
cents each.
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