FRIDAY, SEPTEMBER 14,1962 THE MICHIGAN DAILY IDArlip IMMUM4 ..DYSPEME 4,162T E MIHG N Al PAGTHREE i,. Spotlight on Research with Mlinda Berry cU Bendix To Host Arms Symposium The Pathology Laboratory is the final and indispensable link in the medical chain which seeks to iden- tify and uncover the nature of a disease and its effects on the cells, tissues, organs, and fluids of the body. Without the clinical pathologist and his microscopic, chemical, :bacteriological and other labora- tory tests and procedures, the phy- sician would often be at a loss to make precise identifications con- cerning certain diseases-diabetes and leukemia, for example, can be positively identified only by lab- oratory tests. Major Functions The Department of Pathology at the University performs three ma- jor functions-teaching, service and research: 1) All medical and dental stu- dents take certain required courses in pathology. In addition, the de- partment maintains its own four- year residency program. 2) The department is adminis- tratively responsible for many of the clinical pathology tests at Uni- versity Hospital, and last year over half a million clinical tests were performed. It has built up a li- brary which has been storing and maintaining slides since 1895. 3) A recent report from the department shows 67 research projects currently underway. Experiments Chosen To show the diversity of the work conducted in the various lab- oratories three experiments have been chosen. A number of interlocking re- search projects, sponsored by the Atomic Energy Commission, the United States Public Health Serv- ice, and United Cerebral Palsy Re- search and Education Foundation have been taken on by the neuro- pathology lab. Malformations Because cerebral palsy, mental retardation, and some kinds of blindness are associated with mal- formation of the brain, laboratory work was undertaken to produce malformed brains in albino rats by radiation. These abnormal brains can thus be used as labor-' atory models for study. The brains of all these animals are removed and sectioned for mic- roscopic study, which makes it possible to see the cellular se- quence of events from the first injury to the final malformation. Radiating Rats Dr. Samuel P. Hicks, of the pathology department, has done research showing that radiating rats at various times in the em- bryonic and fetal development of the nervous system kills certain cells and stops them dead in their tracks. Staining sections of brain tissue shows the cells that are stopped, thus demonstrating which cells are doing what at the time of radiation. The ultimate goals of this re- search in neuropathology are to find out more about the kinds of brain malformations in certain diseases and to correlate kinds of brain malformations with behav- orial abnormalities. But before re- search can attack malformations and anomalies with any hope of success, behavorial patterns for normal animals must be worked out. Definite Results Over the years that Dr. Hicks has been carrying out this re- search at Harvard and the Uni- versity, certain definite results have emerged. It is now known that the adult, fully developed ner- vous system is not radio resistant, and that radiation damage may occur past the early embryonic stages. Research on human, testicular cancer, particularly teratomas, is being conducted by Dr. G. Barry Pierce, Jr., of the pathology de- partment. His project, along with those engaged in by several associates, is supported by the Public Health Service, the American Cancer So- ciety and the University Cancer Research Institute. A cancerous teratoma is a malig- nant growth occurring most fre- quently in the ovaries and in the testes. The. growth is composed mainly of a disorganized array of brain, bone, muscle, and glandular cells. Dr. Pierce's laboratory has shown that these cells, which are not themselves malignant, are de- rived by a type of embryonic de- velopment from highly malignant cancer cells also present in the tumors. May Be Incorrect Since the normal-appearing tis- sues derived from the cancer have been shown to be benign, the theory that "once a cancer cell always a cancer cell" may be incor- rect. This could feasibly have im- portant applications in other can- cer work. The pathology labs have worked out an apparatus which elimiates all bacteria from the food and at- mosphere within it. Thus they are able to produce germfree animals, such as the guinea pigs they are currently working with. Gastrointestinal Tract The bacteria normally living in the gastrointestinal tract of ani- mals are absent from these raised in this germless world. As a re- search tool, germfree animals are becoming more and more impor- tant in experimental pathology. Germfree research is now con- ducted by Dr. Gerald L. Brody, professor in the medical school, and Jane E. Bishop, assistant in research in the pathology depart- ment. Since it is manifestly impossi- ble to eliminate all bacteria from laboratory animals, the guinea pigs used in germfree research must be born germfree. This is accomplish- ed by caesarean section. Because these animals then live in a con- trolled environment and because the otherwise uncontrollable vari- able of bacterial flora is removed from them, they present a highly standardized, uniform research subject. Germfree animals can be used for determining the role of bac- terial flora in the ordinary life processes, such as in nutrition. Germfree animals can also be used as a "culture medium" to study the ecology of microorganisms in the living body. The pathology department, with its 67 1962 working projects, is in its 125th year at the University. It was written into the Organic Act of 1837 which established the University at Ann Arbor, that the Medical School should have one professor of pathology. By MALINDA BERRY An International Arms Control Symposium, which will receive the attention of Washington and for- eign officials will be held Dec. 17 through Dec. 20 at the University. It will be the first known sym- posium of its type to be held in the world and could be an asset to U.S. foreign policy on disarma- ment. Russell D. O'Neal, vice president of Bendix Corp., and Roger W. Heyns, vice president for academ- ic affairs are co-chairmen of the symposium. Major Academic The purpose of the International Arms Control Symposium is to "assemble specialists from major academic and industrial research The main speakers are expected to define broad arms control pol- icy problems, recommend solutions and suggest possible roles of gov- ernment, industry, and universi- ties in relation to arms control. The symposium will also high- light the research necessary in po- litical science, the social sciences and the physical sciences ". . . to provide an adequate system for the formulation, verification and com- pliance with possible agreements for international arms control and disarmament," Heyns and O'Neal said. Research Contracts The symposium is an outgrowth of two research contracts the Ben- dix System Division has with the recently formed United States Arms Control and Disarmament Agency. University faculty have been consultants on the first contract and the University itself is prime subcontractor on the second con- tract. The first contract-worth $150,- 000-calls for the "consideration of the production of strategic de- livery systems such as long-range missiles and bombers capable of delivering nuclear weapons," said Louis B. Young, general manager of Bendix Systems. Techniques To Detect The Bendix study will include "techniques for detecting possible 'clandestine production' of stra- tegic nuclear delivery systems," said William C. Foster, director of the ACDA. The ACDA, according to Foster, contemplates a substantial re-, arch program -through govern- ment agencies The second contract concerns a $95,000 allotment for the analysis of the verification requirements associated with specific arms con- trol and disarmament proposals. Ernest S. Van Valkenburg of Bendix Systems and Norman Tho- burn of the Institute of Science and Technology are assistant co- chairmen of the symposium. Details of the contracts and the work to be undertaken are not available, Thoburn said, because much of the work is classified. "Because of the possible ramifica- tions in Geneva, extremely close security checks are understandably required by the Agency." One symposium objective re- volves around a search through which basic and applied research can be brought to bear on the technological, strategic and politi- cal aspects of arms control and disarmament. 9o M t. THREE REASONS WHY YOU'LL LIKE OUR Bachelor 'Bundlo* 1. Everything comes back to you clean and fresh and just raring to be shown off. 2. Our sympathetic seamstresses, mindful that a needle is a lethal weapon in the hands of a mere male, replace all missing buttons and make minor repairs. .. on the house. 3. You'll like our prices. You'll agree our Bachelor Bundle is a best buy. Just ask for Kyer's "BACHELOR BUNDLE." We'll do the rest. *The cuties in the picture, we'll have to confess, were put in to catch you eye. But girls do like men who are nicely groomed 1 ROGER W. HEYNS . .. arms symposium centers as well as representatives from various national and interna- tional organizations." It will provide a current sum- mary of the status of arms con- trol and disarmament, and offer an opportunity for the participants to present international objectives compatible with their national se- curity." Names of the key speakers are to be announced later. They will feature eight major addresses - two a day. model laundry' and cleaners a , ,_: _1 5 :,.p'. { P r' ' -- Ii 627 South Main Street "SPECIALISTS IN FABRIC CARE" 601 East Williams' Phone NO 3.4185 1023 East Ann 1100 Broadway For ALL of your Photographic needs- "PURCHASE FROM PURCHASE" for everything photographic Just What You've Needed for-Your Books! .t . ^.'aI f~ 2I - y 3 ' }.. r[ j j " ., } ..... r Ann Arbor's only Exclusive Camera Shop AUTHORIZED DEALER for most nationally advertised Merchandise Design it yourself... To Fit Your Space and Needs I - I So east's So eoonoMfoafl 9417 11 Q z N. of O e ;i'7 Ansco Argus Bell and Howell Beseler Bolex Eastman Kodak Exakta Graf lex Pentax Ilford ' Konica Leica Minolta Minox Polaroid Praktiflex Revere Rol leiflex Wollensak Yashica }Countless Units can be designed with these 4 PANEL SIZES t------t -I -- £ You don't have to be an engineering major to design and assemble your own bookcases, room- dividers, or TV and Hi-Fi units with Erecta-Shelf. It's fun ... simple ... practical and inexpensive. By combining just 4 panel sizes in satin black or gleaming brass wrought iron, there's no limit to the number of arrangements you can design to fit your space and needs. Note that straight panels con be used horizontally or vertically... and horizontol panels may be attached at any desired height on the vertical panels. EASY TO ADD TO OR TAKE APART Anytime you wish to make your unit taller, longer or deeper simply odd more Erecta-Shelf panels.. . or change the arrangement completely. It's a cinch to disassemble for moving too. Plan your unit (we'll help you if you wish) and come in for your Erecta-Shelf panels and free detailed brochure. WE R- PRICE UST s I 1 I 1 1 1 1 1 I " 1 1 t t i tm . r r r r r N I r r r Ir Vertica 3w3aebsts Consists of7.20" Puu1 4.30" Panels, 4 Wood Bases. Assembled SIG 60"IX22Le Television and Phone Unit/o te"S Consists of 6G3W Panels, 6.24N Pane, 6-20" Panels, 8 dafts Assembled Sie Consists of 2.0" Pat 6 Wood Bases. Asal OSff llokess Consists of 11.241ftm l 6-30n Panels, 4 Wood Oases. Assembrled 3101 ener Stwoer Case or Room MthOde Consists of 4.20" Pne 5.24" Panels, 2.30" Panels, 6 Corner Panet. 7 Wood Bases. A-sa~ the 50aKit ' jIC I f IJNtcPa ------ PU£ ~ /VI1 R CHAE . 'd Prompt Photo Finishing 11 CAMERAS REPAIRED 1 "- Satin Slac wean iS S finish a _____________ . ---- - I- in ur own repair shop I 20" Panel 24" Panel 30" Panel Corner Panel 1.99 ea. 2.39 eo. 2.89 eo. 3 99 en 2.99 ea. 3.39 ea. 3.89 ea. 5.99ena. (2A"x24") !4V' I I I 1 5 Vv.. air. . %#I Irv %4.'! nL'T f a .4.77 GV. 1 .4.77 r.Y. I m -A--,-, , - -, " , a - - -* U I