PAGE SIX

THE MICHIGAN DAii.V

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k~1JUAY, 9APIL 1965

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Center

To

SWEATERS

expand

Genetic

Research

* Lightweight

By CAROL GODOSHIAN

As part of the continued growth
* V Neck of the Medical School, the human
genetics department has been able
H i-Styleto expand to include in its re-
search the origin of hereditary di-
seases and the overall process of
- 8995 . . heredity.
-It s not really clear where our
studies in human genetics will
TICE1S MEN'S SHOP derstanding the genetic context
and physical basis of hereditary
9:00-5:30 Mon. & Fri. till 8:30 diseases and ultimately toward
1 109 So. University Campus Village understanding man as a genetic
organism," Acting Chairman of
the Human Genetics Department
kk UAC
'I
,. MUS
Petitioning will be open in the fall
for the following positions:
TREASURER PROPERTI ES
PROGRAMS MAKE-UP
PROGRAM ADVERTISING LIGHTING
TICKETS & USHERS TECHNICAL DIRECTOR
fyCOORDINATING ARTIST STAGE MANAGER
.:...... ..::::;.3.}:::: ,...<.. . 4. . . - .. . ..

Dr. Myron Levine said in discuss-+
ing the plans and projects of the
department.
"The department nearly dou-
bled a few years ago," Levine said.:
This growth led to the construc-
tion of the newly-opened Law-+
rence D. Buhl Research Center+
for Human Genetics. Additional
facilities similar to those in the
Buhl Center are now being'
planned.
Halfdof the $500,000 building
cost was contributed by the Buhl
family of Detroit. The rest of the,
money came from the United
States Public Health Service.
"Some of the latest and most
sophisticated equipment is avail-
able, including facilities for work
with isotopes and biochemical
techniques," Levine commented.
"There is a great emphasis on
the metabolic diseases that are not
infectious but hereditary," heI
said. It is toward this interesti

conducted on the molecular level,
where, for example, the enzymatic
functions controlled by viruses are
investigated, to studies on the
level of whole populations where
the extent, types and frequency
of hereditary traits among differ-
ent kinds of people are investi-
gated.
One project deals with the rela-
tion between human chromosomes
and diseases. Study is directed to-
ward understanding chromosome
anomalies that might be connect-
ed with hereditary diseases like
mongolism and congenital malfor-
mation. Dr. Margery Shaw 1s1
supervising this project.
In a second lab, under the di-
rection of Dr. Robert S. Krooth,
isolated cells from individuals
manifesting heritary diseases are
being grown in culture. The cells
are examined to see how they dif-
fer from normal cells. "It is hoped
that some day these cell lines may

that the studies of the human serve as materials for crossing
genetics department are directed. i experiments," Dr. Levine said.
Research ranges from projects Another project, under Dr.

Richard E. Tashian, studies here-
ditary enzymatic alterations in
red blood cells. It is concerned
with the chemical definition of
the alterations in the cells and
with the evolutionary conse-
quences of these alterations.
Two labs, supervised by Dr.
Charles M. Radding- and Levine,
are studying the relationship be-
tween phage (bacterial virus) and
bacteria.
These projects are aimed at
studying how temperate phage
establish themselves within bac-
terial cells and their effect on
those cells.
The temperate phage does not
destroy the bacterium it infects.
Instead, it establishes a state,
known as lysogeny, within the
cell by incorporating itself into
the genetic material of the bac-
terium and thus modifying the
genetic activity of the cell.
Understanding the genetic in-
teraction between phage and bac-
teria is important, Levine said, for
it could serve as a basis for a
model to explain certain human
diseases. For example, some peo-
ple believe that cancer results
from a virus that behaves like
lysogenic phage.
Most of the department's re-
search outside the Buhl Center
is concerned with the blood and
hereditary variations of the blood,
from both the biochemical and
population genetics approach. Dr.
D. L. Rucknagel, Dr. Henry Ger-
showitz and Dr. Donald C. Schaef-
fler are among those conducting
their research outside the center.
One of these projects is in-
vestigating the possible genetic
effects of the atomic bombs drop-
ped at Hiroshima and Nagasaki.
This research is being conducted
in Japan by Chairman of the
Human Genetics Department Dr.
James V. Neel and Dr. W. J.
Schull.

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PICTURED ABOVE IS THE new Lawrence D. Buhl Research
Center for Human Genetics. The $500,000 building, financed by
the Buhl family of Detroit and by the U.S. Public Health Service,
is part of the continuing expansion of the Medical School.

School Timep
is
OLYMPIA
TIME Or
University Typewriter Center
613 E. William St. 665-3763

"t

Across Campus


FRIDAY, APRIL 9
8 a.m.-Peace Corps Placement
Test will be held in the lower
lobby o fthe Union.
10 a.m.-The Michigan Junior
College Association Conference
will meet at the Michigan Union.
10:30 a.m.-His Royal Highness
Bernhard, Prince of the Nether-
lands, will speak at the Under-
graduate Honors Convocation at
Hill Aud.
2 p.m.-Open Blood Clinic Day

WILKINSON LUGGAGE SHOP
YOUR LUGGAGE AND TRUNK
HEADQUARTERS

1

..................

I

'a

THIS EVENING
REFORM SERVICE

(student conducted)
FRIDAY, APRIL 9, 7:30 P.M.
SERMON by DR. RICHARD C. HERTZ
Rabbi, Temple Beth El, Detroit
"WHAT IS YOUR JEWISH IDENTITY?"
followed by informal discussion
Organ by courtesy of Grinnell Bros.
B'NAI B'RITH HILLEL FOUNDATION
Zwerdling-Cohn Chapel ALL ARE INVITED 1429 Hill St,

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at the American Red Cross Sub-
Center, 2729 Packard Road.
3:45 p.m.-M. 0. Burrel of Na-
tional Aeronautics and Space Ad-
ministration Space Flight Center
will speak on "Proton Penetration
Calculations" at Cooley Aud. on
North Campus.
4 p.m.-Joseph V. Swintosky of
Smith, Kline and French Lab-
oratories will lecture on "The Bio-
logical Half-Life concept and Its
Applications," at the Chemistry-
Pharmacy Bldg.
4:15 p.m.-James J. Gibson of
Cornell University will speak on
a subject to be announced in a
Psychology Colloquium at Aud. C,
Angell Hall.
7 and 9 p.m.-Cinema Guild will
present Michaelangelo Antonioni's
"Il Grido (The Outcry)" at the
Architecture Aud.
8 p.m.-The Dept. of Speech
University Players will present
Bertolt Brecht's "Galileo" in True-
blood Aud.
8 p.m.-The Deutsche Verein
vocal concert will be held in Aud.
A.,
8:30 p.m.-John A. Williams will
speak on "A Close-Up of' the
Moon" during an astronomy dept.
Visitors' Night at Aud. D.
8:30 p.m.-Melvin Jones, cornet,
will hold a degree recital at the
School of Music Recital Hall.
8:30 p.m.-The School of Music
will present Collegium Musicum,
directed by Robert A. Warner at
Rackham Lecture Hall.
SATURDAY, APRIL 10
8:30 a.m.-'he United Nations
Association will hold a conference
at the Michigan Union.
8:45 a.m.-Registration of the
Conference for Teachers of Dri-
ver Education will be held in the
Rackham Lobby.
4:15 p.m.-Hans Wallach of
Swarthmore College will spear on
a subject to be announced in a
Department of Psychology col-
loquium in Aud C.
4:30 and 7 p.m.-The School of
Music will present recitals by
Roiert Clark, organist, in Organ
Stuaio 2110 of the School of Mu-
sic.
7 and 9 p.m.-Cinema Guild will
present "Sunrise" at Architecture
Aud.
8 p.m. - Tne Department of
Speech university Players will
present Bertolt Brecht's "Galileo"
in Trueblood Aud.
8:30 p.m.-The School of Music
will present a University Wood-
wind Quintet Recital in the Rack-
ham Lecture Hall.
8:30 p.m.-The School of Music
will present a recital by trumpet
and cornet students in the School
of Music Recital Hall.

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3 IS THE LAST DAY OF
for
.4
April 9
10:00 A.M.-4:00 P.M.
II
at the Student Publications Bldg.
420 Maynard Street
r 0 Allpersons holding receipts are requested to pick up

Foot Lockers from ,7.75
Complete Assortment of ALL
size trunks to the large 39x23x21"
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AN ADDITIONAL 10%
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SPRINGTIME IS PHOTOTIME
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1.

Those final T.G.'s
- Your room at the Quad
Your housemother
The West Physics
Building

' Your college friends (?)
* Your Chem lab
Schwartz (that
green dog)
A The General Library
Collection Box

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A Proud New Address
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