University of Michigan School of Music Presents 1969-1970 FESTIVAL OF CONTEMPORARY MUS IC (last concert in the series) pa 4e tlrte ( IxP i t Ftlt ttit NEWS PHONE: 764-0552 BUSINESS PHONE: 764-0554 Tuesday, November 4, 1969 Ann Arbor, Michigan Page Three LSD study finds no chromosome damage Wednesday, November 5-8:00 P.M. RACKHAM LECTURE HALL SEYMOUR SHIFRIN, guest composer WEBERN-"Drei Gesonge, Opus 23" Michele Derr, soprano Ellwood Derr, piano SH IFRIN--"String Quartet No. 5" Stanley Ouartet BERRY-"Des Visages de France" Michigan Chamber Ensemble Lynda WestonrRosemary Russell, soloists Theo Alcantara, conductor SHIFRIN-"Chamber Symphony" Michigan Chamber Ensemble Theo Alcantara, conductor NO ADMISSION CHARGE Space provided by Pi Kappa Lambda Gi j iii{ '' i F __ __ CHICAGO ("P)-In contrast to pre- vious studies, three researchers reported yesterday that the use of LSD does not cause significant changes in the users" chromosomes. The research had been spurred by widespread concern among doctors about possible effects of the drug on chromosomes, the carriers of genes. If such damage had occurred, the chil- dren of LSD users might have been born with physical or mental defects. LSD is the popular abbreviation for lysergic acid diethylamide, an hal- lucinogenic drug which has had wide- spread illicit use. The researchers said the results of their studies "would seem to sustain the conclusion that at this time there is no definitive evidence that LSD damages chromosomes of human white blood cells." "However," they added, "further research in this complex field is obviously needed." The research was conducted by three Maryland doctors with a grant from the National Institute of Mental Health. The findings appeared in the Nov. 3 issue of the Journal of the American Medical Association. Criticizing the earlier investigations of the matter, the researchers said one major shortcoming uniformly char- acterizing previous studies was the ab- sence of adequate control measures. "Most important, the chromosomal aberration rate prior to the alleged taking of LSD was not assessed," they said. "With the goal of providing a more definite answer, we undertook a larger prospective study," they added. For the study the investigators used 32 patients already scheduled to re- ceive LSD as part of the psychiatric treatment. at the Spring Grove State Hospital, Baltimore. The patients were hospitalized for alcoholism or neurotic problems and had never taken LSD previously. All volunteered to be subjects in a study of the potential of LSD in psychiatric treatment. The subjects ranged in age from 20 to 56 years oldl, and included five fe- males and 27 males. Both high-dose and low-dose groups were studied. Their statistical analysis, the re- searchers said, "revealed no significant difference in the chromosomal aber- ration rates before and after taking LSD for either the high or low dose groups whether analyzed separately or as one group." "Our findings are in contrast to the four studies which have reported more chromosomal aberrations in LSD takers than in normal controls," the researchers wrote. They said other research failed to take into account chromosomal ab- erration before the use of LSD, infec- tions in the users, the use of other drugs with LSD, impurities present in homemade LSD, and other factors. PRESENTS Under the High Patronage of Her Majesty, Elizabeth II, THE ROYALj CHORAL SOCIETY accorn panied by the j ROYAL CHORAL SOCIETY PLAYERS conducted by WYN MORRIS TONIGHT AT 8:30 IN HILL AUDITORIUM PROGRAM: HANDEL................... ........ Coronation Anthem HODDINOCT ..... .. Ervri (composed for the Investiture of Charles, Prince of Wales 1969) First Time in America BEETHOVEN ...............................Mass in C Major Tickets: $7.00, $6.50, $6.00, $5.00, $3.50, $2.50 THE UNIVERSITY MUSICAL SOCIETY ' Burton Tower, Ann Arbor, Michigan 48104 Hours: 9:00 to 4:30 Mon. thru Fri.; Sat. 9:00 to 12:00 (Also l % hours before performance at Rgckham Auditorium) the 1t news today by TFhe Associated Press and College Press Service ARAB GUERRILLAS reached a settlement of their differ- ences with the Lebanese government. In a communique issued after seven hours of negotiations in Cairo, Yasir Arafat, leader of the Palestine Liberation Organization, and Gen. Emile Bustani, Lebanon's army commander, cited their brotherly ties and common destiny as the main reasons for the agree- ment designed to guarantee both Palestinian interests and the sov- ereignty of Lebanon. BLACK PROTESTERS snarled traffic in downtown Memphis, Tenn. while students boycotted the schools. For the fourth straight week, about 65,000 students and 650 teachers stayed away from classes to enforce demands that the Memphis school board include more black representation in school affairs and to aid a predominately black strike against a local hos- pital. In addition, about 4000 marchers staged two traffic-snarling marches through the downtown streets of Memphis, and still man- aged to avoid a major confrontation with the police. The street mai'chers have been continuing on an almost daily basis for the dura- tion of the month-long protest period. Leaders of the newly-formed Negro-coalition said a fifth Mon- day school boycott would be staged next week, when the Rev. Ralph David Absrnathy, head of the Southern Christian Leadership Con- ference will lead the march. R* PRESIDENT NIXON'S first budget is expected to exceed $200 billion. Despite a general order to government agencies calling for stringent cost-cutting, high administration officials speculated that outlays in fiscal 1971 would be about 10 billion higher than the target originally set by the administration. Defense costs received the chief blame for the increase in ex- penditures, and officials conceded that unless there were major changes in the war effort, the $5.9 billion surplus which Nixon had promised will not be met. Nixon strength to OFF-YEAR ELECTIONS face test From Wire Service Reports Both the political strength of the White House and big- city political trends will be tested today in several important off-year elections. Gubernatorial elections are slated for New Jersey and Virginia, while New York, Cleveland, and Detroit will select mayors. The only congressional race involves the seat in New Jersey's 8th district, where the incumbent resigned to become a state court judge. Both gubernatorial races are considered significant be- cause President Nixon has traveled to each of the states to campaign personally for the two Republicans. In Virginia, Nixon backed Linwood Holton, a Republican with the backing of civil rights and labor leaders, in his bid to end the Democrats' 83-year hold on the statehouse. Wil- liam Battle, his Democratic 00 1 O er opponent, was rated a slight C o ipose favorite, however. Nixons choice in New Jersey was William T. Cahill, a six-term congressman who is r u nn i n g t : against former Democratic Gov. Robert B. Meyner. The contest has been rated a toss-up. g ' 4