16 April 25 • 2019 jn E ver since Dr. Jeffrey Band gradu- ated medical school at University of Michigan in 1973, he’ s been busy saving lives. Now semi-retired, the former chief of infectious diseases and international medicine at Beaumont Health spends time traveling and enjoy- ing his family, but still makes plenty of time for his passions: seeing patients periodically, consulting with the health department and teaching medical students at Oakland and Wayne State universities. Here he talks about the Michigan measles outbreak. What about those who say “no one in Michigan has died because of the measles, so it’ s hard to feel it’ s really so dangerous. ” For every 1,000-2,000 cases of measles, there may be a death. In the pre-vaccine era, when there were a million or so cases of measles annually, there used to be several thousand deaths per year due to measles. At the last count, Michigan’ s outbreak numbered 43. It’ s a matter of numbers — hopefully, we won’ t get to those numbers. Some people think the MMR vaccine is just as dangerous or more dangerous than the measles. What’ s your opinion? It’ s almost unheard of for someone to die from the MMR vaccine. MMR is one of our safest vaccines. In comparison, 1 of every 1,000-2,000 people who develop the measles will die. I would think pur- posely exposing someone and deliber- ately trying to contract the measles is like playing with fire. My own children were certainly immunized. I had no hesitation what- soever. Of course, I want to protect my family members to the best of my ability. Jewish law says to protect ourselves and our neighbors. Except for people who cannot be immunized or who had a previous severe reaction to an MMR, I cannot think of a single reason not to immunize. Some people seem to think that not vaccinating is a passive choice. I disagree; not immunizing is an active decision to remain susceptible to serious diseases. How often do you see complications from the MMR vaccine? About 5-10 percent of people will devel- op a low-grade fever or a small rash from the vaccine. Because it’ s a live vac- cine, there’ s a small chance that a flu-like illness will appear after administration. It is extremely rare, but some people also have serious reactions to the vaccine, in which case, of course, they should not get a second dose. Adults who receive the MMR can sometimes develop painful joints for a while or experience a decrease in their platelet count although it will return to normal within a week or so. An extremely rare reaction of the MMR is febrile seizures, which can occur in approximately 1 out of 2,500- 5,000 doses. Some people cannot receive live viral vaccines — pregnant woman, patients with immune-compromised conditions and people who’ ve experienced a severe reaction to a previous vaccine. What about reports about a link between the MMR and autism? This claim can be traced to a 1998 publication by Andrew Wakefield who had a small number of kids enrolled in a study where he supposedly found a link between vaccines and autism. That study spread and spread — it was more contagious than measles! Later, the publication was proved fraudulent with manipulated data. Some of the parents of the children in that study even came forward saying things like, “That never occurred with my child!” Almost every co-author on the paper retracted their name. The report was removed from medical publications, but by then it had already been published. Wakefield was found in a court of law to have commit- ted fraud among other things and his license was revoked. The silver lining to this whole story was that it spurred further studies on the topic. The largest test studied 500,000 patients in Denmark and found no association whatsoever with autism. In fact, an American study in 2015 followed 100,000 children with an increased risk of autism — they had a family member with autism — and still found no cor- relation. In fact, it was discovered there was a lower risk for autism in kids who were vaccinated, even those who had a sibling with autism, than those who weren’ t. It seems many people here who got the measles were vaccinated. Why didn’ t the MMR work for them? At least 97 percent of people develop immunity after receiving the vacci- nations at the right time. There is still approximately 3 percent of the pop- ulation it just won’ t work for, people who would receive the benefits of herd immunity if most of the community is vaccinated. Additionally, vaccines are complicated things. The MMR contains two parts — the live part and then the solution it’ s put in. Until the two parts are mixed, one part is kept in the freezer and one in the refrigerator during the entire time it’ s transported from the company to the doctor’ s office or health department. If those temperatures are mixed up, it could destroy the vaccine. The MMR is also light-sensitive. Once it’ s drawn up, if it’ s exposed to light for more than a few hours, it could become inactivated. Pediatricians have had a lot of expe- rience with giving childhood vaccines, but now adults who only received one shot as recommended when they were kids are going to their internists for their booster, but how much do these doctors know about “childhood” vaccinations? Do they know how to store them prop- erly? There is so much involved that some physicians are not comfortable with administering vaccinations and refer their patients elsewhere. Why are close-knit communities like Orthodox Jews most prone to getting measles? Two main reasons. One, there’ s a higher rate of vaccine refusal these days, in gen- eral. It’ s not just these groups — you find it everywhere, in every community, in many select populations. Most importantly, this population is one big extended family, attend many common events and go to synagogues or places of worship as a daily part of their lives. There’ s a lot more potential for spread in these close-knit communities. Can the outbreak be contained and eradicated? Absolutely. The local health depart- ments have done a wonderful job iden- tifying the sites of exposure, finding people who may be at risk and getting them evaluated. Some people then received a vaccine, which is still effec- tive within 72 hours after exposure, and were isolated just in case to keep them from potentially spreading the disease to others. I can’ t predict when it will end, of course, and I do get nervous with Passover coming up and the family events that come with it, more people traveling, etc. But once we get past this period, I do think it will get under con- trol. It’ s due to a diligent system of sur- veillance and intervention — it works. We eradicated measles once before in 2000, and I have hope we will do it again. ■ jews d in the The Scoop on MEASLES Q&A with Dr. Jeffrey Band, an infectious disease expert. ROCHEL BURSTYN CONTRIBUTING WRITER Dr. Jeffrey Band