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44
the cells of the duodenum
professor in the division of gastroen
terology, said, "One of the frustrating
aspects of the biology of pancreatic
cancer
is that the
cancer
round themselves with
cells
scar
small intestine next to the
that may indicate the presence of pan
creatic
sur
tissue
responding
To Test Or Not?
Several questions from the audience
to the presence of the
makes it difficult for anti-cancer
to
focused
This barrier around the tumor
cancer.
penetrate
drugs
the blood vessels that
collapse.
BEFORE
This dramatic
veneers were
and deliver
melanoma;' said Diane Simeone,
M.D., director, Pancreatic Cancer
I
29829
new
PeriodonJics / DenIid lmpkmJ>
www.drnemeth.com
2000260
genetic mutations (a blood test) will be
can-
assessed and
studies for
impact on
with
patients'
said.
•
•
Stober,
M.D.
'.
-
studies show that
emphasized that
maintaining healthy lifestyle includ
ing exercise, observing good nutrition
and avoiding the development of Type
Personalized
are
care
are
abnormally
cancer cells.
looking
a
for
Simeone said
specific
number of genes
active in
Scientists
pancreatic
someday be able to isolate these genes
samples.
865�4160
s
-
t�("1?4\1
.
46 July
30
•
2015
IN
on
.
niques that may detect pancreatic
in its
early stages are being
developed. These techniques will allow
doctors to look for subtle changes in
cancer
.
major step to pre
included not
She also
2 diabetes
are
important preventive
.
approaches.,
"Make
cancer
which is
early,
why research
finding pancreatic cancer
before it spreads. New imaging tech-
centers
a
cancer
a
predict they will
pancreatic
pancreatic
smoking.
in blood
.
-
being
comprehensive on
site diagnostics
•
..
are
smoking because 25 percent of pan
creatic cancers are directly related to
<
248
promising treatment options
in pan
more
genes and changes within genes asso
ciated with pancreatic cancer. Initial
leon Morris, D.O. Allan Ross, M.D.
Sheldon Stoffer, M:D • Gary Yashinsky, M.D.
or
expertise
and where new,
location that has
•
248�865�4150
cancer
vent
.
_
clinical and research
creatic
researchers
PLEASE CALL TODAY TO SCHEDULE
YOUR APPOINTMENT WITH OUR PHYSICIANS:
Richard
multidisciplinary environment with
Accessible
is found
•
patients with pancreatic cancer par
ticipate in clinical trials. We are only
going to make inroads in pancreatic
cancer if patients are cared for in a
developed:'
ment comes when
M.D.
specific genetic
"Unfortunately, only 6 percent of
the DNA of each
The best chance for successful treat
Eugene Herman,
cells, the
mutations.
"By sequencing
and identifying the primary
mutations for a specific cancer, we
can identify the
drug combinations
most likely to be effective for a specific
patient against a specific cancer:'
In pancreatic cancer, damaged or
from your visit to
your phone calls
.
stem
abnormal genes cause uncontrolled
cell growth. Using genetic analysis,
physician
•
cancer
and treatments for
cancer
health
improve
system, the stroma (connec
tive tissue cells) of the cancer tissue
distinct ways, it makes sense to look
at each cancer individually;' Crawford
dedicated to their
mild
for patients
cancer, but not the
immune
a cancer is driven
by sev
potential genetic mutations, each
driving the cancer's progression in
physicians
pancreatic
als that target
cancer
"When
Board certified
some
breakthrough needed;' she said.
"Therapeutic approaches that have
merit are being tested in clinical tri
eral
•
imaging
or
high risk.
at
patients
"We have had
research.
excellence in care,
where the patient comes first.
be ordered. Guidance
ment in outcomes
cell survival:'
an
can
provided about the pos
sible need for surveillance
landscape that
controls how cancer cells respond to
collagen. Our idea is to jam the signals
the collagen receptors send to the
tumor cells disrupting their interaction
Crawford described how personal
Providing
also be
illustrate the molecular
ized medicine has
fam
happen by a cancer genetics
that germline analysis for
expert
can
cancer
a
cancer
so
Fridman and me, partially funded by
the Sky Foundation, is beginning to
and
and/or
colon
should
cells;' he said. "Research by Dr.
cer
Telegraph Rood, Suite 111 I Southfield, Michigan 48034
or
Center, University of Michigan. "If
either of these is present, evaluation
role in
plays important
supporting the survival of the
cancer
of breast
or
evidence that
an
pancreatic
ily history
chemotherapy directly to
collagen, major component of the
fibrotic environment of pancreatic
Associates
assess
with
tumors,
248.357.3100
testing a
a
consultation, 0011248-357-3100.
knowledgeable physician to
familial risk for pancreatic cancer if
you have two or more family members
promising drug that relieves pressure
on the blood vessels so they open up
"There's also
change is the result of a gum reshaping procedure. No other procedures or
used. Drs. Nemeth and Katranji offer many procedures to enhance a smile.
Joseph R. NemethDD
a
often
the tumor.
AFTER
For a smile
they
A clinical trial is
and when.
cancer
"You should seek information from
stream and creates so much pressure
on
who should be tested for
on
pancreatic
they leave the blood
once
cancer.
or
fibrosis, which is created by normal
cells
(part of the
pancreas)
sure
your doctor takes
a
thorough history about your family's
history of cancer to ensure you are not
at increased risk for the development
of pancreatic cancer'tSimeone said.
"This is a disease that often requires
a
multidisciplinary approach, working
with
a
team of experts. Seek
a
second