health & wellness Hope For Hot Flashes Local doctors offer varied solutions for minimizing symptoms. Hormone Therapy Ruthan Brodsky I Contributing Editor lushed faces, sweat beads on foreheads, car windows open in winter and the hum of the hand- held fan — all signs of women having hot flashes. Hot flashes are symptoms of perimeno- pause and menopause. These short and recurring episodes of intense heat are reported by 75 percent of premenopausal and menopausal women in the United States. That's 45 to 50 million women who may be sticking their head and shoulders in open freezer doors when a flash occurs. Perimenopause generally begins when a woman's menstrual periods are incon- sistent. "Perimenopause is an extended transitional state and can last for years, but menopause is an exact point in time says Dr. Robert Robins, a gynecologist/obstetrician in Bloomfield Hills. "The Dr. Robert premenopausal phase Robins usually begins several years before menopause as the ovaries gradually produce less estro- gen. This usually starts in the 40s, but some women start in their 30s. "The average of length of perimeno- pause is four years. At that point, when the ovaries stop releasing eggs and a woman hasn't had a period in 12 months, is when menopause actually begins" F Avoiding Hot Flashes "Hot flashes are often brought on by spe- cific triggers" explains Dr. Jeffrey Obron, a gynecologist/obstetrician and certified menopausal clinician in West Bloomfield. "Avoiding triggers, such as stress, alcohol, caffeine, spicy foods and hot showers, may reduce the number of hot flashes and their intensity for some women. "Other natural behaviors that work for some women are keeping the core body temperature down by wearing clothes made of wicking materi- al, keeping cool water at their bedside and using Dr. Jeffrey air conditioning or ceil- Obron ing fans" Obron says. "Maintaining an ideal weight also helps because obese women tend to have a higher incidence of hot flashes:' 46 October 31 • 2013 JN Just over a decade ago, millions of American women were using combination hormone replacement therapy (HRT) to help manage their menopausal symptoms. That changed in 2002, when scientists at the National Institutes of Health (NIH) halted the Women's Health Initiative (WHI) study in which women were taking combination estrogen and progestin. Data showed that those women were at increased risk of breast cancer, heart attack, stroke and blood clots. Millions of women tossed their HRT prescriptions in the garbage. "Use of hormone therapy changed when that large clini- cal trial found that the treat- ment actually posed more health risks than benefits, especially when given to older postmenopausal women" says Dr. Robert Goldfarb, senior staff physician, Women's Health Services at Henry Ford West Bloomfield. "Doctors stopped prescribing the ther- apy as the concern about health hazards grew" Then, in 2004, NIH also stopped the estrogen-only study for women who had undergone a hysterectomy. Data showed that this increased the risk of blood clots and stroke and did not reduce the risk of heart attacks for these women. The WHI study is large and compli- cated and often resulted in patient and medical confusion. The saga of HRT has gone from "hormone therapy is good for all women" back in the 1990s to "it's bad for all women" after 2002. After a reappraisal of the study, the results are now broken down by age and time since menopause, positioning the benefits of HRT somewhere in the middle. "The recommendation is not to use hormones for long-term chronic disease prevention because of the increased risk of clots and stroke Goldfarb says. "However, they should be considered for treating younger women with moder- ate to severe symptoms of menopause and whose quality of life has diminished because of severe hot flashes and other menopausal symptoms" Hormonal Options "There are several types of estrogen therapy used in dif- ferent forms" says Dr. Deborah Charfoos, Michigan Women's Health Staff, Beaumont Hospital in Royal Oak. "The type used depends upon the health, symptoms and per- sonal preference of the individual. "Oral medication, pills, is the common form of Estrogen Replacement Therapy (ERT), reducing hot flashes and other menopausal symp- toms" Charfoos says. "However, there's still the risk of strokes and blood clots when taken long term. Estrogen patches pose most of the same risks. Estrogen gels, creams and sprays are absorbed through the skin directly into the bloodstream making them safer than pills for people with liver problems. "The key is balancing the risks of taking hormone therapy against the benefits of not taking a hormone she says. "Patients and their doctors need to work together to figure out which therapy works best" Obron says, At times a good compound pharmacy may be useful, especially when a physician decides that a particular drug is not appropriate for a patient or the patient requires a medication tailored to her special medical needs. They provide custom products with individualized doses and mixtures of products prescribed by the doctor" Robins adds, "Another option for hormone therapy is the bioidentical hormones therapy (estradiol and proges- terone) approved by the FDA. These are hormones biochemically identical to the body's own hormones that are custom compounded" Nonhormonal Options "The U.S. Food and Drug Administration recently approved the drug Brisdelle for the treatment of hot flashes due to menopause Charfoos says. "This is • the first non-hormonal Dr. Deborah treatment to be Charfoos approved by the FDA for hot flashes associated with menopause. Brisdelle contains a selective serotonin reuptake inhibitor, making it unique from all other FDA-approved treatment for hot flashes that contain hormones" Goldfarb says, "Another option is the FDA- approved drugs to treat depression, which are Dr. Robert known to sometimes Goldfarb reduce hot flash symp- toms in women without depression. These include Paxil, Effexor and Lexapro. Others find relief with Neurotin, a drug to treat epilepsy and migraine" Alternative Medicine "Some women also find relief from hot flashes with nonprescription remedies" Obron says. "My advice is to use only those products that have been studied and are manufactured at a reliable location for safety. The problem is many of these products aren't studied and we don't know their risks or side effects" According to Obron, women may also want to consider consuming soy and soy products such as tofu and soy beans, chick peas, lentils, flax seed and red clover. Acupuncture Treatment "Many women look for a more natural and less risky treatment" says Julie Silver, MSW and a certified acupuncturist in Farmington Hills. "I use traditional Chinese acupuncture to reduce Julie Silver the severity of hot flash- es and other menopause symptoms" In 2011, a study was published in the Journal of Acupuncture in Medicine sug- gesting that acupuncture might help reduce the severity of menopause symp- toms. By the end of the 10-week treat- ment, the group of women receiving acu- puncture reported significantly fewer hot flashes and less severe flashes. "Integrating the acupuncture techniques with custom Chinese herbal formulas and a healthy lifestyle usually provides the best results for women with hot flashes" Silver says. Individual treatment is key to deciding whether a woman should enter HRT or select another option for managing her menopausal symptoms. Quality of life, family history and lifestyle are all factors in the problem-solving process between patient and physician. ❑