Health & Fitness

RETIREMENT LIVING

TECHNOLOGY

Breakthrwigh

Children's brain disease examined.

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32 August 6 • 2009

Dr. David Rosenberg, right, explains his research to ABC anchor David Muir.

MC Children's Hospital of
Michigan Chief of Psychiatry
and Psychology David
Rosenberg, M.D., was to be featured on
ABC's 20/20 this week. Dr. Rosenberg
was interviewed at the Detroit Medical
Center at Children's Hospital in June by
ABC news anchor David Muir.
Dr. Rosenberg, the Miriam L.
Hamburger Endowed Chair of Child
Psychiatry and professor of psychiatry
in the School of Medicine at Wayne State
University in Detroit, was highlighted
for his work Ivith a team of researchers
who recently discovered that the brain
chemical glutamate plays a major role
in children with obsessive-compulsive
disorder (OCD).
OCD affects 1-3 percent of the
population worldwide and as many as
80 percent of all OCD cases begin in
childhood and adolescence. Glutamate
functions as the brain's light switch.
The studies found that children with
OCD had abnormal glutamate levels in
key brain regions associated with glu-
tamate gene abnormalities that were
reversible with effective treatment.
Dr. Rosenberg's research, in col-
laboration with researchers at the
DMC Children's Hospital of Michigan,
Wayne State University, University of
Michigan and University of Toronto's
Hospital for Sick Kids, could possibly
lead to new treatments for the debili-
tating neuropsychiatric condition.

'What we are doing. is beginning 1•0

elevate child psychiatry to a level com-
parable to traditional pediatric medi-
cine and neurology in that we now
have a firm basis in the brain anatomy,
chemistry and physiology. and, there-
tbre, a better scientific underpinning
for what we do,- said Dr. Rosenberg.
"We now know that childhood OCD is
a brain disease and this knowledge may
help defeat same of the stigma and prej-
udice children with psychiatric illness
face, like more difficulty .,ret-ting insur-
ance to pay for their treatment, haying
C say, es all in your head,' when, in
fact, these are brain illnes that can be
-d with proper treatment"
One of Dr. Rosenberg's OCD
patients, who is now 18 and is consid-
ered a success story, was also inter-
viewed for the spedal. Since age I L
she has been treated by Dr, Rosenberg.
He says her condition has dramatical-
ly changed and she no longer requires
medication for her OUT).
With mapetic
ante imag*,
we Gm take a axupletely 11011i11
1 VathVe
biopsy of the child brain's amtortm
chemistry and physiolv- with great
power and precision — but with no
shots, needles, radiation or airger; said
Dr. Rosmberg.
"The Nalli study not onh- has
scientific implications but has key
translational relevance in bringing
work from the bench to the bedside
with potentitai clinical ramifications,'
RosattNen,-1 said. L -1

-

Vickie Etters, Julie O'Connor and Philip

Vanhulle work for DMC Children's Hospital

communications department, Detroit.

