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B12
February 12 • 2009
0 M PT
SPECIALISTS
ORTHOPEDIC MANUAL PHYSICAL THERAPY
Haifa
U
sing cancer cells from an
ovarian cancer patient and
human embryonic stem cells,
Israeli researchers have created a can-
cerous tumor in a mouse that mimics
the way the tumor would develop in the
patient's body.
The result is a preclinical experimen-
tal model for cancer research that could
facilitate the development of personal-
ized cancer therapies. The findings are
published in the January 2009 online
version of Clinical Cancer Research.
Until now, there have been very
few pre-clinical experimental models
in, which cancer cells from an actual
patient could be successfully grown
in such a manner, say the research-
ers from the Technion-Israel Institute
of Technology's Rappaport Faculty of
Medicine and Rambam Medical Center.
The team, led by the Technion's
Professor Karl Skorecki and Dr. Maty
Tzukerman, created the model by intro-
ducing a human patient's ovarian can-
cer stem cells into a teratoma (a growth
made up of a mixture of human tis-
sues, including blood vessels, fat tissue
and connective tissue) in a mouse. The
teratoma in the mouse was derived
from human embryonic stem cells.
"Growing cancer stem cells from
the patient in a way that mirrors their
growth in the human body could allow
clinicians to check the sensitivity of
a particular tumor to different treat-
ments," explains Dr. Tzukerman. "This
ability could provide clinicians with
ways to customize cancer treatments
for each individual patient."
These master cells in ovarian and other
cancers appear to be the most important
targets in anti-cancer treatments.
The research findings also empha-
size that the choice of the environment
in which to establish the experimental
platform to grow cells and establish the
tumor model is crucial. ❑
Sinai Guild Grants
DMC and Jewish groups benefit.
T
he Sinai Guild has awarded 13
grants totaling $295,879 to help
Detroit Medical Center hospitals
and organizations that serve the Jewish
community conduct research and pur-
chase medical equipment.
This is the eighth year that the Sinai
Guild Board of Director Grants have
been awarded, with a total of more
than $2 million in grant awards to area
hospitals and organizations.
"These grants fill an important need
because there are very few organiza-
tions that give grants to meet medical
needs both in the Jewish community
and the medical community:' said
Sandra Jaffa, executive director of the
Sinai Guild.
Detroit Medical Center:
• Purchase a Cybex Functional
Trainer to assist occupational therapy
patients with rehabilitation, Detroit
Receiving Hospital — $39,983.
• Purchase a Cerebral/Somatic
Oximeter system for use during pedi-
atric cardiovascular surgery, Children's
Hospital of Michigan — $34,400.
• Purchase a computerized human
patient simulator, Huron Valley-Sinai
Hospital — $34,995.
• Purchase specialized instruments
for orthopedic surgeries: Birmingham
hip replacers, Huron Valley-Sinai
Hospital — $34,484.
• Purchase priority medical equip-
ment: two cystoscopes and one laryn-
goscope, Karmanos Cancer Center
— $25,000.
• Outreach Program for seniors,
Lions Hearing Center — $14,150.
• Purchase two defibrillators,
Orchestra Place Employee Activities
Committee — $2,188.
• Purchase a MOTOmed and Easy
Stand device to benefit patients with
paralysis, Rehabilitation Institute of
Michigan — $32,370.
• Purchase hemoglobin A1C testing
supplies for diabetes program, Sinai-
Grace hospital — $9,654.
• Purchase wall-mounted blood
pressure cuffs — Sinai-Grace Hospital
— $20,655.
Jewish organizations:
• Prescription program for seniors,
Jewish Apartments & Services —
$18,000.
• Purchase a therapeutic tub, Jewish
Apartments and Services — $10,000.
• Purchase medical supplies and
equipment for Tamarack summer
camps, Tamarack Camps — $20,000. ___