Do you know someone wi Gaucher disease? This message could be ver im ortant to the - • • • • • . • • • • . • _ ... • • • • . • • • • . I'm not different because 1 have Gaucher disease. I'm different because of how 1 treat it. - 1 4 r Rich F: businessman, father, beachcomber, Zavesca patient • For adults with mild-to-moderate type 1 Gaucher disease for whom enzyme replacement therapy is not a therapeutic option, there is an alternative. It's an oral medicine and it's called Zavesca. Important Safety Information: In clinical trials, patients treated with Zavesca experienced peripheral neuropathy, tremor, diarrhea, and weight loss. Zavesca may also lead to birth defects if taken by pregnant women and to impaired fertility in men. Men and women should use effective birth control during treatment with Zavesca. ACTE LION fi)ZAVESCAioo, (miglustat) capsules To learn more, call 1-866-228-3546 or visit vvww.zavescaDT.com Please see summary of product information on next page. © 2006 Actelion Pharmaceuticals US, Inc. All rights reserved. ACTU ZAV JA 004 0506 1117370 July 27 2006 21