S AP SHOTS Meet one of the faces of success Michael Chopp, Ph.D., scientific director of the Neuroscience Institute and vice chairman for Neurology-Research at Henry Ford. Hospital in Detroit, is a member of the Henry Ford Medical Group. He is also a distinguished professor of physics at Oakland University in Rochester. Mentors Serve Youth Jewish Family Service of Metropolitan Detroit hosted its first Mingle with the Mentors evening in May at the Andiamo-Second City of Novi. Mentor Connection is a non-sectarian program of Jewish Family Service. It matches school- and community—based men- tors with Oakland County youth who may have low self-esteem, academic shortcomings, a troubled home environment or poor social skills. Above, Connection chairs Richard Cherkasky and Susan Leemaster, both of Franklin, standing, enjoy the Second City Show with the event sponsors, MetroBank President Ronald DiCicco and West Bloomfield Branch Manager Carole McDougall. As a physicist, Michael Chopp had always planned on a career in aca- demics. With a doctorate in physics and mathematics from New York University, it seemed a natural progression. That path encoun- tered a detour many years ago. "In the late seventies, I was asked by a neurosurgeon to watch a pro- cedure on a patient with hydro- cephalus, or 'water on the brain'," says Dr. Chopp. "Watching the pressure in the spinal column as it was being mon- itored, I noticed periodic pulsa-r Eons in the pressure and wondered if this could be interpreted as an indicator of disease." He studied the question in more detail, with the findings of his early studies confirming that the pulsa- tions in spinal pressure were linked to health, and reflected the brain's ability to regulate blood flow. "I made the move from physicist to a researcher of biomedical prob- lems," he says. "In particular, the neurosciences." Dr. Chopp joined Henry Ford 23 years ago to pursue his research interest in the treatment of neurological disease. He has done numerous studies on stroke and brain tumors, helping to better understand the mechanisms of brain cell death and repair. Glorious Kitchens The National Council of Jewish Women/Greater Detroit Section held a "Captivating Kitchens" fund-raising tour of eight designer kitchens to support Meals on Wheels and local community service projects, such as the All Kids Playground in Waterford, Wrapped in Love, Teen Dating Abuse Project and Children's Advocates. A related patron event featuring a silent auction, culinary demonstrations and wine tasting was held at Specialties Showroom in Berkley. The May events were under the leadership of past vice president Irma Glaser of West Bloomfield and, shown above, event chairs Abbey Brasch Nathan of Bloomfield Hills Nancy Josephson of West Bloomfield and Shayna Silverman of Farmington Hills. "What happens to the brain during a stroke?" he asks. "What causes brain damage? How can the death of brain cells be reduced or delayed? Can we develop ways to protect brain cells? These are the key questions we try to answer with our research." the level of understanding of brain func- tion and has led to the development of various treat- ments for stroke and neurological disease. "During the 1990s, we discovered that after the onset of injury the brain produces new proteins and genes, reminis- cent of the developing brain," he says. "The brain actually tries to renew itself by reverting to an ear- lier state of development." The window of opportunity that is offered by this developmental response to injury in the adult brain gives physicians a chance to learn more about how to help patients with multiple sclerosis, Parkinson's disease, and stroke. Dr. Chopp is investigating how the brain might be triggered at the molecular level to restructure itself. "The brain remodels itself," he says. Dr. Chopp has also pioneered the use of cell therapy, particularly with bone marrow, umbilical cord blood cells, and adult stem cells, for the treatment of neurological disease. Henry Ford was the first in the U.S. to administer such cell therapies to treat stroke and neu- rological disorders. Other current studies involve test- ing drugs such as statins, which are medications that lower cholesterol, and other drugs, such as Viagra, to improve neurological function after stroke, traumatic brain injury and neurodegenerative disease. In experimental studies, Dr. Chopp has shown that these drugs restore neurological function, developing the field of restorative neurology. He and his wife are affiliated with Young Israel of Southfield. That research has helped increase For niore intOrmation 01' to make an appointment call 1-80o-FIENRYFORD or visit our Web site www.lienrulard.com iN June 15 • 2006 13