/Health

GENETIC TESTS from page 98

THE

PG

screening for specific conditions,
such as the mutations in the BRCA1
and BRCA2 genes that are linked to
breast cancer. "In high-risk families,
changes in the BRCA genes increase
a woman's risk of developing breast
cancer to 20 percent by age 40, 50
percent by age 50, and 80 to 90 per-
cent by age 80 versus 8-12 percent
lifetime risk for all women," he
pointed out. "There's no 100-per-
cent guarantee that a particular indi-
vidual, given all the possible risk fac-
tors, will develop a particular can-
cer," he cautioned. "What we do
know is that the individual predis-
posed to genetic changes has a sig-
nificantly increased risk that the dis-
ease will develop."
Remembering the Nazi experi-
ments in eugenics, Jews may well be
cautious about the growth of genetic
screening for inherited health risks.
The experts point out that the choice
to undergo genetic testing is a very
personal decision in which individu-
als and the family need to consider
the benefits and the limitations. ._:

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Ruthan Brodsky is a _freelance writer-
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