■ WINTER 1996 ISSUE ■ SINAI HOSPITAL Gynecologic Cancers Early Detection is Crucial T here's both good news and bad news ' about gynecological cancers (cancers of the reproductive organs in women). Many are preventable or curable if they are caught early, but in many cases the cancer is well advanced by the time symptoms appear. Cancers of the lower reproductive tract include ovarian cancer; uterine cancer, which is either en- dometrial cancer (the endometrium is the lining of the uterus) or cervical cancer (the cervix is the neck of the uterus); and cancer of the vagina or vulva. Gynecological cancers strike women of all ages. Endometrial cancer is more common in post-menopausal women; cervical cancer usually occurs in younger women, often those in their early thirties. "Annual gynecological exams are crucial for de- tecting these cancers," Alfred. Sherman, MD, said. Dr. Sherman is Director of the Sinai Hospital Gy- necological Oncology program and a professor of obstetrics and gynecology at Wayne State Uni- versity. "Every woman who is over 18 years of age or is sexually active should have an annual pelvic exam and Pap smear," says Dr. Sherman. 'These procedures are the best ways of finding these can- cers early and finding them early is the key to suc- cessful treatment and survival." Dr. Sherman estimates that about 20,000 new cases of endometrial cancer will be diagnosed in the United States this year. Of those, most will be cured. "We anticipate a 60-70 percent survival rate," he says. "Close to 100 percent of the women whose cancer is detected early and treated with surgery and radiation will survive." Cervical and endometrial cancers can be de- tected in their pre-cancerous states by a Pap smear, which reveals the lesions that precede them. The lesions can then be treated and the cancers prevented. The outlook for those diagnosed with ovarian cancer is less optimistic. Of the approximately 17,000 women who will be diagnosed with ovar- ian cancer this year, about 4,000 will survive. The difference in survival rates may be caused by the difficulty in finding ovarian cancer before it has reached an advanced stage. Usually it can be detected only by a pelvic ultrasound. Ovarian cancers tend to grow and spread quickly. Gilda Radner, comedi- enne and TV and film star, died from ovarian cancer. "We don't have a good clue as to the possible causes of ovarian cancer," Dr. Sherman states. "We do know that a small per- centage of the cases are related to abnormal gene factors, so if a woman's mother had ovarian cancer, she is considered at high risk. We also know that women who have taken birth control pills for an extended period, five to ten years, seem to have a low- er risk of ovarian cancer." Researchers don't know the causes of gynecological cancers. There is some indication that en- dometrial cancer may be relat- ed to hormone disturbance. Viral infection may be one of the fac- Laparoscopic surgery allows doctors to look for signs of gynecologic cancer and tors in cervical cancer. With so remove tumors through small incisions rather than by conventional surgery. little information available, it uterus — through a small incision rather than may be impossible to assess an individual's risk through conventional surgery. Not only can this of developing one of these diseases. "The mor- be used when performing a hysterectomy for non- bidity associated with these diseases underscores the need for continued research in this area. The malignant disease, but it can be incorporated into support of the community as participants in clin- the diagnostic procedures performed if there is suspicion of cancer. A laparoscopy does not re- ical trials, as well as donations to support research quire hospitalization and it is far less invasive activities, are of paramount importance as feder- than traditional abdominal surgery. al funding continues to decline," comments Vic- Many gynecologic cancers are treatable, even ki Baker, MD ; Section Chief of Gynecologic curable. It is very important to seek medical at- Oncology at the University of Michigan Medical tention if you have any abnormal symptoms. Sinai School and Associate Section Chief of Gynecolog- will provide you with the best medical care avail- ic Oncology at Sinai Hospital. able. We will also continue to improve the diag- Treatment for gynecological cancers has ad- nosis, technology and treatment options available vanced a great deal in recent years. Sinai was one to women. The earlier cancer is treated, the bet- of the first hospitals to use an instrument called ter the results. a laparoscope, which allows doctors to inspect the ovaries and uterus — and even to remove the Antenatal Birthing Classes before birth has occurred Obstetrician educational classes to inform expectant parents about the birthing process, what to expect, and ways to improve the experience for both parents and baby a doctor who specializes in the medical care preceding and immediately after the birth of a baby Obstetrics area of medidne which deals with birth and with the time before and after the birth Lactation Consultant LDRP nurse with special training about breast feeding Pediatrician labor/delivery/recovery/postpartum room. The mother is admitted to one room during labor, remains there for the birth of the baby and through her entire stay in the hospital. a doctor who specializes in the development, care and diseases of children Pediatrics OB Nurse Practitioner area of medicine which deals specifically with children Neonatologist a doctor who specializes in the development, care and diseases of newborn babies Perinatologist physician who is specially trained to take care of pregnancies with risks to mother and fetus NICU neonatal intensive care unit. Usually categorized as level 3 for more complicated cases after birth has occurred Non-stress Test one of a series of tests (e.g., monitoring fetal movements and heartbeat) that are used to determine the well-being of the baby before birth Postnatal Postpartum Prenatal before birth has occurred OB ICU intensive care unit staff by specialists in both intensive care and obstetrics nurse with specialized training to deal with the mother and baby before, during and after birth the time period during the first six weeks following delivery of a baby