Scanned image of the page. Keyboard directions: use + to zoom in, - to zoom out, arrow keys to pan inside the viewer.

Page Options


Something wrong?

Something wrong with this page? Report problem.

Rights / Permissions

The University of Michigan Library provides access to these materials for educational and research purposes. These materials may be under copyright. If you decide to use any of these materials, you are responsible for making your own legal assessment and securing any necessary permission. If you have questions about the collection, please contact the Bentley Historical Library at bentley.ref@umich.edu

December 01, 1995 - Image 57

Resource type:
The Detroit Jewish News, 1995-12-01

Disclaimer: Computer generated plain text may have errors. Read more about this.

Explore the Alternatives
to Promote Good Health

tions should join with Chabad's
Children of Chernobyl in en-
couraging Dr. Baverstock and the
WHO Thyroid Cancer Project to
verify the actual effect of in-
creased Jewish susceptibility to
post irradiation thyroid cancer
on Chernobyl's current victims.

Protein Regions
Aid Insulin Action

particular protein region
seems to play a key role in
the cell's response to in-
sulin, according to a Weiz-
mann Institute study described
in the July 28, 1995, issue of the
Journal of Biological Chemistry.
Because loss of response to in-
sulin is one of the causes of dia-
betes, this finding may some day
contribute to the development of
new ways for treating this dis-
Insulin is a hormone formed
in the pancreas and released into
the bloodstream in order to pro-
mote the uptake of glucose from
the blood by the body cells. Dia-
betes, which affects millions of
people worldwide and is the third
leading cause of death, is caused
either by insufficient insulin pro-
duction or by a lack of proper re-
sponse to the insulin on the part
of target tissues. The new study
has pinpointed a region in the
target cells that is necessary for
a normal response to insulin.
Cells sense the presence of in-
sulin via specialized receptors
that protrude through cell mem-
branes and initiate biochemical
changes inside the cell. The
Weizmann team, headed by Pro-
fessor Yehiel Zick of the depart-
ment of chemical immunology,
deleted a region of the cell pro-
tein IRS-1, which is a biochemi-
cal link in the insulin signaling
pathways, and found that insulin
signaling was disrupted. This re-
gion, called the plackstrin ho-
mology domain, plays an
important role in insulin action.
This conclusion is supported
by similar findings in a Harvard
Medical School-U.S. National In-
stitutes of Health study report-
ed in the May 19 issue of the
Journal of Biological Chemistry.
Professor Zick's team, which
included departmental colleague
Dr. Daniel Schindler and Ph.D.
students Dr. Hedva Voliovitch
and Yaron Hadari, collaborated
with Drs. Simeon Taylor and
Domenico Accili.
The plackstrin homology do-
main contains.about 120 amino
acids grouped into six main
blocks. The Weizmann team re-
moved four of these blocks, and
found that this prevented the
protein IRS-1 from taking on



Front, Left to Right: Kim L. Miller, M.D. and Robert C. Levine, M.D.
Rear, Left to Right: David Brownstein, M.D. and Jeffrey E. Nusbaum, M.D.

Our group of family practice physicians are board certified
in their field. They provide a full range of medical services
including gynecology and pediatrics. The "no scalpel" vas-
ectomy is a procedure available at our office. In addition,
some of our physicians have special training in holistic and
alternative medicine. This includes vitamin and nutritional
therapy, manipulation, acupuncture and hypnosis.

We offer evening hours and Saturday appointments to accom-
modate our patients' busy lifestyle.

Farmington Hills Family Practice

Wayne Stale University

32910 W. 13 Mile Rd. #C301

Huron Valley

Farmington Hills, Michigan 48334
Telephone: 810-851-1600

c_r 0


Tell them you want a Leo Knight Portrait
Because you deserve the very best








Twenty-one Wonderful Years Of Experience
From The Tradition To The Glitz

• Weddings • Bar/Bat Mitzvahs
•Hebrew Calligraphy • Birth Announcements
• Calligraphy & Mailings • Stationery
•Hostess Gifts • Hand Holding And Smiles


The thoughtful gift that shows how much
you care! Avoid the crowds...
gift certificates can be
purchased by phone.


Invitations 25% Off
with this ad



Ve4,144:1 law:ate:dad

Debbie Goldfine Weisserman
810-569-9792 • Tower 14 • Southfield

N. N.. N.
. e. e . F.




N. • N. • 1. • •

• e

. /. e


N. N. . 5. • N.

,. ,. ,. •.

• . N. • .. .• • N, •
I. 1. I. e• e.

• N. •
F .

p S . N.. %.

e. e.

e. •.

26571 West. Twelye Mile Road at Northwestern Hwy.

(810) 352-7030


Back to Top

© 2020 Regents of the University of Michigan