The Situation In Israel The great AIDS panic that has swept through most of the world has not yet reached Israel. But it is probably on the way. So far, 40 cases of AIDS have been diagnosed in Israel and 33 of these vic- tims have died. A further 239 people have been diagnosed as carriers of AIDS antibodies. The Israel Health Ministry recently set up a committee to prevent the spread of AIDS. Among the sugges- tions so far are that volunteers from abroad coming to work on kibbutzim should be screened for AIDS, as should army conscripts and pregnant women. In swinging 1bl Aviv, where AIDS consciousness is higher than other parts of the country, public health officials have opened an information hotline and are now preparing literature and lectures on the subject for local schools. Haviva Avi-Guy, who holds the city council's public health portfolio, recently suggested that condom dispensers be installed in the restrooms of all cafes and other entertainment spots in the ci- ty (condom sales in. Israel doubled from 400,000 packages in 1985 to 800,000 last year, and are expected to double again in 1987). Avi-Guy's suggestion, however, has so far been stymied by fierce opposition from three religious council members, who consider that such a move would represent an endorsement of pre-marital sex and immorality. They also point to the continued rabbinical ban on the use of condoms. The council is meanwhile working on a plan to provide regular AIDS screen- ing for Tel Aviv's 400 known male and female prostitutes. According to a 1986 survey of 70 pro- stitutes who "work" the city's 1bl Baruch beach area, 5 per cent of the women and 20 per cent of the men were found to be AIDS carriers—statistics similar to those found in Los Angeles and San Francisco. Dr. Donald Silverberg, head of 1bl Aviv's Public Health Department, says only a small percentage of AIDS vic- tims in Israel are known to have become infected as a result of drug use. But this figure, he fears, will grow, creating a major problem,. if AIDS- infected addicts turn to prostitution to cholesterol in order to be infective. The AIDS (or HIV) virus is one of them. "Once we realized that," says Professor Shinitsky, "we decided to concentrate all our efforts on developing a treatment that would reduce the cell cholesterol level in AIDS patients." The initial results were promising and, inevitably, a world frantic for a means of dealing with a threatened AIDS epidemic seized on the "Israeli egg yolk treatment." The stampede of patients began soon after. But Professor Shinitsky and his medical colleagues are determined that they will not be stampeded. They cannot begin to help everyone seeking their treatment for the simple reason that supplies of AL-721—which are produced at the Weiz- mann Institute—are limited, and Israeli patients come first. Moreover, supplies will remain limited until the treatment has been thoroughly tested and evaluated. The Weizmann In- stitute has sold exclusive rights to pro- duce, develop and market AL-721 to a Los Angeles-based company, the Ethigen Cor- poration (until recently known as Praxis Pharmaceuticals). The company has obtained FDA ap- proval for the use of AL-721 on an ex- perimental basis and is planning a large-scale, controlled study on AIDS vic- tims in the United States and Israel. If the results are as good—and early tests indicate that they will be—AL-721 will be marketed commercially early next year. According to Professor Shinitsky—who has studied at the University of Illinois in Urbana, the National Institute of Health in Bethesda, Maryland, and the Duke Uni- versity Medical Center—the international medical fraternity has so far shown only cautious interest in the treatment. "They don't relate to something so un- sophisticated and simple," he says wryly. "They prefer something more abstract, more esoteric, more elusive than an inex- pensive substance extracted from egg yolks." Dr. Skorknick, however, believes that medical interest in AL-721 will quicken once the Israeli research data is published and the American trials are completed. In the meantime, the Israeli doctors struggle to treat as many patients as possi- ble within the limits of their restricted sup- plies and budgets. Dr. Skorknick, 47, frets about the fact that for reasons of scarcity, he is able to treat only patients in advanced stages of the disease. He is anxious to test AL-721 on victims in the early stages of the disease and, support their drug habit. A proposed AIDS clinic, however, has raised hackles all over the city. One fro- posed site was mysteriously burned down and neighborhood residents have given loud and clear expression to their opposition. Israel's religious community has also shown a growing concern about the possible spread of AIDS among the observant. Rabbis from the organization Medi- cine According to Halacha have recent- ly discussed the problem and noted that "AIDS carriers cannot have sexual rela- tions, which are intended for healthy people only." They are particularly concerned that newly observant Jews.-1` returning from a world in which there is excessive lust'"—may bring the virus into their new communities. Recently, representatives of the organization were dispatched to the United States to determine whether there is a disinfecting agent that can be put into the mikve (ritual bath) to pre-. vent the spread of the disease through this medium. ❑ perhaps even more important, on people who are carriers of the AIDS virus but whose health has not yet been impaired by i t. Kaplan Hospital and the Rokach- Hadassah Medical Center may not, accord- ing to guidelines laid down by Israel's Health Ministry, charge patients a cent for treatment because AL-721 is still experimental. While some patients do make a donation to the AL-721 research program, others, ac- cording to Professor Shinitsky "forget even to say thank you." So far, Professor Shinitsky has de- veloped AL-721 for the ludicrously low sum of $10,000—all from his modest de- partmental budget—and he admits to a twinge of envy when he reads about Elizabeth Taylor and her showbiz super- star friends raising millions of dollars for the fight against AIDS. But he plods on in the hope that his AL-721 "baby" might one day prove to be a vital element in the race to head off an AIDS epidemic. And he still hopes to return to his research, now shelved, into ag- ing and that other scourge of modern man, drug addiction. One way or another, Meir Shinitsky is determined to put the much-maligned egg yolk back on the map. ❑