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July 01, 1983 - Image 44

Resource type:
Text
Publication:
The Detroit Jewish News, 1983-07-01

Disclaimer: Computer generated plain text may have errors. Read more about this.

44

Friday, July 1, 1983

THE DETROIT JEWISH NEWS

Weizmann Institute Wins Leukemia Grants

JEWELRY
APPRAISALS

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At Very Reasonable
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LAWRENCE M. ALLAN
President
149, GEMOLOGIST 6,1 DIAMONTOLOGIST

Hours: Daily til 5:30, Sat. til 4:30

NEW YORK — The
Weizmann Institute of Sci-
ence has received six grants
from the Leukemia Re-
search Foundation of
Chicago for ongoing inves-
tigations of that disease by
its scientists.
The six Weizmann re-
search projects that were
selected account for 45 per-
cent of the more than
$418,000 being dispersed in
grants this year 1:iy the
foundation's medical advi-
sory board. A total of 16
projects were selected from
65 grant applications sub-
mitted by universitities and
research centers around the

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world for consideration.
In 1982, seven Weizmann
projects figured in the 17
awarded by the Foundation.
Heading the Leukemia
Reseach Foundation's
list of grant recipients
this year is Weizmann's
Dr. Yair Reisner, who
will receive support for
follow-up studies aug-
menting his recent suc-
cess in the development
of bone marrow trans-
plants between "incom-
patible," genetically un-
related individuals. Dr.
Reisner of the institute's
department of biophysics
was awarded an initial
grant by the foundation
in 1982.
It was his research, in
association with clinicians
at New York's Memorial
Sloan - Kettering Cancer
Center, that accounted for
the medical breakthrough
which has been responsible
for the rescue recently of
eight children with immuno
- deficiency disease and one
with advanced leukemia.

Dr. Reisner's findings
have opened the door to ap-
plications in treating
leukemia, sickle cell
anemia, thalassemia and
other blood disorders, and
certain immune deficien-
cies and congenital defects,
which affect 14,000 people a
year in the United States.
Dr. Reisner's work re-
flects a continuity of three
generations of Weizmann
scientists involved with this
research and its fruition. In-
itiated in the 1960s, it
began as an investigation
into the plant proteins by
Dr. Nathan Sharon, head of
the institute's biophysics
department and Dr.
Reisner's mentor. In the
early stages of that re-
search, Dr. Sharon was

joined by his teacher, Prof.
Ephraim Katzir, later Is-
rael's fourth president.
In the late 1970s, that
work turned to focus on
the unexpected and
ser mdipitous role played
by soybean lectin — a
plant protein — in a cell
separation technique
that, by eliminating let-
hal, killer T-cells, pointed
the way to permitting
bone marrow transplan-
tation between mis-
matched donors. Prev-
iously only identical
twins — and sometimes
parents and siblings —
could be used as donors.
As a doctoral student, Dr.
Reisner worked closely with
Dr. Sharon during this
animal - laboratory phase
and, as a result, was invited
to bec-ome a research associ-
ate at Memorial Sloan -
Kettering Cancer Center.
In collaboration with the
center's staff, he advanced
and refined the cell separa-
tion technique that is cen-
tral to the transplant pro-
gram.
This program is ' now
being introduced to institu-
tions in the U.S., England
and Germany. In Israel,
bone marrow grafts are
scheduled for this- year in

Decision to Hold UN Parley
in Geneva Draws Protests

GENEVA (JTA) — The
Federation of Swiss Jewish
Communities has protested
vehemently to President
Pierre Auber over his gov-
ernment's decision to host
the United Nations Confer-
ence on Palestine in Geneva
from Aug. 29 to Sept. 7. -
In a letter to Auber, who
is also Foreign Minister, the
Jewish body said it would

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Don't pass up this Terrific Opportunity!

Tel Aviv's Sheba Medical
Center and at Tel
Hashomer Hospital and in
the Hadassah - University
Hospital in Jerusalem.
In addition to Dr.
Reisner's new grant for
"transplantation for acute
leukemia with histo-in-
compatible parental mar-
row cells fractionated by
lectins," the other Weiz-
mann scientists selected by
the Leukemia Research
Foundation and their re-
spective areas of research
are:
Drs. David Givol and
Mia Horowitz, activation
of oncogenes by DNA re-
arrangement;
Dr. Ben Zion Shiloh,
study of the drosophila
melanogaster genes
homologous to the cellular
oncogenes abl and src;
Dr. Moshe Oren, relation-
ship of p53 to malignant
transformation in mouse
and man;
Dr. Dov Zipori, functions
of stromal cell lines from
hemopoietic organs; and;
Drs. Michael Feldman
and Shraga Segal, the
acquisition of metastatic
properties by non-
metastatic plasmacytomas
and lymphomas, via soma-
tic cell hybridization.

strive up to the last minute
to prevent the conference
from being held here be-
cause it is incompatible
with the essence of the UN
Charter. The letter con-
tended that the Palestine
conference will not serve
the cause of peace but will
only support - those who as-
pire to destroy Israel.
Auber met with the
Minister of Police yesterday
to discuss preparations for
the conference. They said at
a press conference later that
2,000 persons are expected
to attend, including the
delegates, the secretariate
and the press. The confer-
ence, to be paid for by the
UN, is estimated to cost $6
.million. It was switched to
Geneva after the French
government refused to have
it in Paris, the original site,
and the Austrian govern-
ment ruled out Vienna.
The main problem
cited by the various gov-
ernments was security,
particularly the danger
that the gathering could
attract terrorist ele-
ments. Strong political
pressure was brought to
bear by Israel and its
friends to deny the con-
ference any meeting
place.
The Swiss press is almost
unanimously opposed to the
conference. The Journal
D'Geneve warned today
that in view of the rebellion
now going on in the Pales-
tine Liberation Organiza-
tion, the city may be turned
into a battlefield. "We in
Geneva are accustomed to
host conferences on peace,
not conferences inciting to
hatred," the paper said in an
editorial.

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